Cassava Sciences, a clinical-stage biotechnology company, reported a decrease in research and development expenses to $16.2 million in Q1 2024, down from $22.1 million in Q1 2023, primarily due to the completion of patient screening and enrollment for their Phase 3 clinical program. General and administrative expenses also decreased by 16% to $3.7 million, largely due to a reduction in legal expenses. The company saw a change in fair value of warrants, resulting in a gain of $43.0 million for the quarter. Interest income decreased slightly to $1.8 million. Cassava Sciences' lead therapeutic drug candidate, simufilam, is in Phase 3 clinical studies for the treatment of Alzheimer's disease dementia, with top-line results expected by year-end 2024 and mid-year 2025 for their two studies. The company's investigational diagnostic product...Show More

Cassava Sciences, a clinical-stage biotechnology company, reported a decrease in research and development expenses to $16.2 million in Q1 2024, down from $22.1 million in Q1 2023, primarily due to the completion of patient screening and enrollment for their Phase 3 clinical program. General and administrative expenses also decreased by 16% to $3.7 million, largely due to a reduction in legal expenses. The company saw a change in fair value of warrants, resulting in a gain of $43.0 million for the quarter. Interest income decreased slightly to $1.8 million. Cassava Sciences' lead therapeutic drug candidate, simufilam, is in Phase 3 clinical studies for the treatment of Alzheimer's disease dementia, with top-line results expected by year-end 2024 and mid-year 2025 for their two studies. The company's investigational diagnostic product, SavaDx, is a blood-based diagnostic for Alzheimer's, though its development is deprioritized compared to simufilam. Cassava Sciences has not generated revenue from product sales and has an accumulated deficit of $355.7 million as of March 31, 2024. The company's cash and cash equivalents stood at $124.2 million, which they believe is sufficient to fund operations for at least the next 12 months. Cassava Sciences' financial strategy includes potential future funding through public or private financing.