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CRISPR Therapeutics | 10-K: Annual report

CRISPR Therapeutics | 10-K:年度報表

SEC announcement ·  02/21 20:55
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CRISPR Therapeutics, a leading gene editing company, has reported significant developments in its annual financial report. Financial Performance: The company has not disclosed specific revenue, operating profit, net profit, or diluted earnings per share for the entire year. However, it has recognized $370.0 million in collaboration revenue for the year ended December 31, 2023, primarily related to agreements with Vertex Pharmaceuticals. Additionally, grant revenue amounted to $1.2 million. Business Development: CRISPR Therapeutics has made strides in its business development, with the landmark approval of CASGEVY, the world's first CRISPR-based gene-editing therapy, for the treatment of severe SCD or TDT. The company has also advanced multiple gene-edited cell therapy programs for oncology and autoimmune diseases, and initiated Phase 1 clinical trials for...Show More
CRISPR Therapeutics, a leading gene editing company, has reported significant developments in its annual financial report. Financial Performance: The company has not disclosed specific revenue, operating profit, net profit, or diluted earnings per share for the entire year. However, it has recognized $370.0 million in collaboration revenue for the year ended December 31, 2023, primarily related to agreements with Vertex Pharmaceuticals. Additionally, grant revenue amounted to $1.2 million. Business Development: CRISPR Therapeutics has made strides in its business development, with the landmark approval of CASGEVY, the world's first CRISPR-based gene-editing therapy, for the treatment of severe SCD or TDT. The company has also advanced multiple gene-edited cell therapy programs for oncology and autoimmune diseases, and initiated Phase 1 clinical trials for in vivo gene editing programs targeting cardiovascular disease. Future Plans: The company plans to continue expanding its clinical trials, including initiating a trial for CTX112 in systemic lupus erythematosus and expanding trials of CTX131 into hematologic malignancies. It also aims to advance its portfolio of in vivo programs and develop gene-edited stem cell-derived therapies for the treatment of Type 1 Diabetes. CRISPR Therapeutics is focused on innovating next-generation editing modalities through its CRISPR-X research team and establishing internal manufacturing capabilities for clinical and commercial production of its product candidates.
領先的基因編輯公司CRISPR Therapeutics在其年度財務報告中報告了重大進展。財務業績:公司未披露全年的具體收入、營業利潤、淨利潤或攤薄後的每股收益。但是,它已確認截至2023年12月31日的年度合作收入爲3.7億美元,主要與與Vertex Pharmicals的協議有關。此外,贈款收入爲120萬美元。業務發展:CRISPR Therapeutics在業務發展方面取得了長足的進步,CASGEVY獲得了具有里程碑意義的批准,CRISPR Therapeutics是世界上第一種基於CRISPR的基因編輯療法,用於治療嚴重的SCD或TDT。該公司還推進了針對腫瘤學和自身免疫性疾病的多個基...展開全部
領先的基因編輯公司CRISPR Therapeutics在其年度財務報告中報告了重大進展。財務業績:公司未披露全年的具體收入、營業利潤、淨利潤或攤薄後的每股收益。但是,它已確認截至2023年12月31日的年度合作收入爲3.7億美元,主要與與Vertex Pharmicals的協議有關。此外,贈款收入爲120萬美元。業務發展:CRISPR Therapeutics在業務發展方面取得了長足的進步,CASGEVY獲得了具有里程碑意義的批准,CRISPR Therapeutics是世界上第一種基於CRISPR的基因編輯療法,用於治療嚴重的SCD或TDT。該公司還推進了針對腫瘤學和自身免疫性疾病的多個基因編輯細胞療法項目,並啓動了針對心血管疾病的體內基因編輯計劃的1期臨床試驗。未來計劃:該公司計劃繼續擴大其臨床試驗,包括啓動 CTX112 治療系統性紅斑狼瘡的試驗,以及將 CTX131 的試驗擴大到血液系統惡性腫瘤。它還旨在推進其體內項目組合,開發用於治療1型糖尿病的基因編輯幹細胞衍生療法。CRISPR Therapeutics專注於通過其CRISPR-X研究團隊創新下一代編輯模式,併爲候選產品的臨床和商業化生產建立內部製造能力。

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