| | |
每股
|
| |
合计
|
|
公开发行价
|
| |
$16.00
|
| |
$213,333,328
|
|
承保折扣(1)
|
| |
$1.12
|
| |
$14,933,333
|
|
未扣除费用的收益给我们
|
| |
$14.88
|
| |
$198,339,995
|
|
| 美国银行证券 | | |
Jefferies
|
| |
瑞士信贷
|
|
| 贝伦伯格 | | | | | |
Kempen&Co
|
|
| | |
第
页
|
| |||
招股说明书摘要
|
| | | | 1 | | |
风险因素
|
| | | | 15 | | |
有关前瞻性陈述的告诫声明
|
| | | | 82 | | |
使用收益
|
| | | | 84 | | |
股利政策
|
| | | | 85 | | |
企业重组
|
| | | | 86 | | |
大写
|
| | | | 87 | | |
稀释
|
| | | | 88 | | |
选定的合并财务信息
|
| | | | 89 | | |
管理层对财务状况和经营成果的讨论和分析
|
| | | | 91 | | |
业务
|
| | | | 113 | | |
管理
|
| | | | 213 | | |
主要股东
|
| | | | 227 | | |
关联方交易
|
| | | | 229 | | |
股本及章程说明
|
| | | | 234 | | |
荷兰公司法与美国公司法比较
|
| | | | 243 | | |
符合未来出售条件的普通股
|
| | | | 255 | | |
征税
|
| | | | 257 | | |
承销
|
| | | | 273 | | |
产品费用
|
| | | | 281 | | |
法律事务
|
| | | | 282 | | |
专家
|
| | | | 282 | | |
判决执行
|
| | | | 282 | | |
在哪里可以找到更多信息
|
| | | | 283 | | |
财务报表索引
|
| | | | F-1 | | |
| 发行商 | | | CureVac B.V.,将在本次发售结束前转换为CureVac N.V.并重命名为CureVac N.V.。 | |
|
发行普通股
|
| | 我们提供13,333,333股普通股。 | |
|
承销商购买额外普通股的选择权
|
| |
我们已授予承销商在本招股说明书发布之日起30天内向我们额外购买最多1,999,999股普通股的权利。 |
|
| 同时私募 | | | Dietmar Hopp先生已同意在本次发行完成的同时,以每股16.00美元的价格从美国购买总价值1亿欧元的普通股。一旦消费了此次发售,霍普先生将通过一家附属实体DH-LT-Investments GmbH实施此次购买。本次收购将由霍普先生根据同时定向增发进行。本次发行的结束不以同时私募结束为条件。 | |
|
本次发行后发行的普通股
|
| |
175,968,204股普通股(如果承销商全面行使购买额外普通股的选择权,则为177,968,203股普通股),假设我们在同时的私募中向霍普先生发行和出售7,375,000股普通股。 |
|
|
投票权
|
| | 我们的普通股每股有一票投票权。 | |
| 列表 | | | 我们的普通股已获准在纳斯达克全球市场或纳斯达克上市,代码为“CVAC”。 | |
|
收益使用情况
|
| | 我们估计,在扣除承销折扣和佣金以及我们应支付的发售费用后,我们从此次发行中获得的净收益将为(I)约194.8欧元(如果全部行使承销商购买额外普通股的选择权,则为224.5美元)和(Ii)同时私募获得的额外净收益1亿欧元。我们目前打算使用此次发行和同时定向增发的净收益,以及手头的现金和现金等价物如下:(I)通过完成第三阶段,为公司的SARS-CoV-2 mRNA疫苗计划提供资金;(Ii)为公司短期生产能力的扩大提供资金;(Iii)通过完成第二阶段临床试验,推进公司的主要肿瘤学计划CV8102;(Iv)通过完成第二阶段临床试验,推进公司的狂犬病疫苗计划CV7202。(V)投资进一步开发本公司的mRNA技术平台,并推进其他临床前和临床项目的开发;及(Vi)将剩余资金用于营运资金和一般企业用途。请参阅“收益的使用”。 | |
|
股利政策
|
| | 我们从未就我们的普通股支付或宣布任何现金股息,我们预计在可预见的未来不会对我们的普通股支付任何现金股息。我们打算保留所有可用的资金和未来的任何收益,为我们业务的发展和扩张提供资金。在公司重组完成时,根据荷兰法律,我们只能在股东权益(Eigen Vermogen)超过缴入股本和催缴股本之和加上荷兰法律或我们的公司章程规定的准备金之和,以及(如果涉及利润分配)在股东大会通过年度账目后支付股息,因为大会似乎允许这样的股息分配。在该等限制的规限下,未来是否派发股息将由我们的管理委员会在我们的监事会批准下酌情决定,并将取决于一系列因素,包括我们的经营结果、财务状况、未来前景、合同限制、适用法律施加的限制以及我们的管理委员会和监事会认为相关的其他因素。 | |
|
锁定协议
|
| | 我们已与承销商达成协议,除某些例外情况外,在本招股说明书发布之日起180天内,不会提供、出售或处置我们股本中的任何股份或可转换为、可交换或可行使的任何股份的证券。我们的董事总经理和监督董事,以及我们几乎所有的现有股东,都已同意基本上类似的锁定条款,但某些例外情况除外。 | |
|
风险因素
|
| | 有关在决定投资我们的普通股之前应考虑的因素的讨论,请参阅本招股说明书中包含的“风险因素”和其他信息。 | |
|
定向共享计划
|
| | 应我们的要求,承销商已预留最多40万股普通股,或本招股说明书拟发行普通股的3%,通过定向股票计划以首次公开募股(IPO)价格出售。通过定向股票计划购买的普通股将不受锁定限制,除非我们的任何董事或高级管理人员购买的普通股除外。我们不知道这些潜在投资者是否会选择购买全部或部分分配的股份,但可供公众出售的普通股数量将减少到这些个人或实体购买此类预留普通股的程度。承销商将按照与本招股说明书提供的其他普通股相同的基准向公众发售任何未如此购买的预留普通股。 | |
| | |
截至的年度
12月31日 |
| |
用于三个-
个月截止 3月31日 |
| ||||||||||||||||||
| | |
2018
|
| |
2019
|
| |
2019
|
| |
2020
|
| ||||||||||||
(单位为千欧元,不包括每股金额)
|
| | | | | | | | | | | | | |
(未审核)
|
| |||||||||
营业报表和全面收益(亏损)数据:
|
| | | | | | | | | | | | | | | ||||||||||
收入
|
| | | | 12,871 | | | | | | 17,416 | | | | | | 3,156 | | | | | | 3,119 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | | | | | (7,558) | | | | | | (5,475) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | | | | | (198) | | | | | | (330) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | | | | | (10,862) | | | | | | (10,902) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | | | | | (6,887) | | | | | | (11,495) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | | | | | 732 | | | | | | 1,995 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | | | | | (108) | | | | | | (127) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | | | | | (21,725) | | | | | | (23,216) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | | | | | 649 | | | | | | 1,041 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | | | | | (90) | | | | | | (1,719) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | | | | | (21,166) | | | | | | (23,894) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | | | | | (142) | | | | | | 44 | | |
本年度净亏损
|
| | | | (71,241) | | | | | | (99,873) | | | | | | (21,308) | | | | | | (23,850) | | |
其他综合损益: | | | | | | | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | | | | | 36 | | | | | | 48 | | |
本年度综合亏损总额
|
| | | | (71,175) | | | | | | (99,841) | | | | | | (21,272) | | | | | | (23,802) | | |
|
| | |
截至2020年3月31日
|
| |||||||||||||||
| | |
实际
|
| |
专业
形式(1) |
| |
形式
调整后(2)(3) |
| |||||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||||||||
财务状况数据报表: | | | | | | | | | | | | | | | | | | | |
现金和现金等价物
|
| | | | 43,474 | | | | | | 626,804 | | | | | | 791,876 | | |
总资产
|
| | | | 155,656 | | | | | | 738,986 | | | | | | 904,058 | | |
总负债
|
| | | | 199,313 | | | | | | 132,235 | | | | | | 132,235 | | |
总股本
|
| | | | (43,657) | | | | | | 606,751 | | | | | | 771,823 | | |
| | |
截至2020年3月31日
|
| |||||||||||||||
| | |
实际
|
| |
形式
|
| |
形式
作为 调整后(1) |
| |||||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||||||||
现金和现金等价物
|
| | | | 43,474 | | | | | | 626,804 | | | | | | 791,876 | | |
可转换贷款
|
| | | | 67,078 | | | | | | — | | | | | | — | | |
股权(2): | | | | | | | | | | | | | | | | | | | |
已发行资本
|
| | | | 743 | | | | | | 19,431 | | | | | | 21,031 | | |
资本公积
|
| | | | 495,327 | | | | | | 1,135,950 | | | | | | 1,299,421 | | |
累计亏损
|
| | | | (539,797) | | | | | | (548,700) | | | | | | (548,700) | | |
其他综合收益
|
| | | | 70 | | | | | | 70 | | | | | | 70 | | |
股东权益总额
|
| | | | (43,657) | | | | | | 606,751 | | | | | | 771,822 | | |
总市值
|
| | | | 23,241 | | | | | | 606,751 | | | | | | 771,822 | | |
| | |
$
|
| |
€
|
| ||||||
普通股首次公开发行(IPO)价格
|
| | | | 16.00 | | | | | | 13.56 | | |
预计2020年3月31日每股普通股有形账面净值在给予
对(一)2020年民间投资的完善,(二)对完善的影响 同时向霍普先生定向增发1亿欧元我们的普通股 每股价格相当于本次公开发行价格的股票,(Iii) 向Dietmar Hopp先生和(Iv)我们的 全额偿还可转换贷款 企业重组 |
| | | | 4.36 | | | | | | 3.69 | | |
可归因于新投资者的每股普通股有形账面净值增加
|
| | | | 0.78 | | | | | | 0.66 | | |
预计为公司重组和发售生效后于2020年3月31日调整后的每股普通股有形账面净值
|
| | | | 5.13 | | | | | | 4.35 | | |
向新投资者摊薄每股普通股
|
| | | | 10.87 | | | | | | 9.21 | | |
新投资者每股普通股摊薄百分比
|
| | | | 67.9% | | | | | | 67.9% | | |
| | |
截至的年度
12月31日 |
| |
这三个
个月截止 3月31日 |
| ||||||||||||||||||
(单位为千欧元,不包括每股金额)
|
| |
2018
|
| |
2019
|
| |
2019
|
| |
2020
|
| ||||||||||||
| | | | | | | | | | | | | | |
(未审核)
|
| |||||||||
营业报表和全面收益(亏损)数据: | | | | | | | | | | | | | | | | ||||||||||
收入
|
| | | | 12,871 | | | | | | 17,416 | | | | | | 3,156 | | | | | | 3,119 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | | | | | (7,558) | | | | | | (5,475) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | | | | | (198) | | | | | | (330) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | | | | | (10,862) | | | | | | (10,902) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | | | | | (6,887) | | | | | | (11,495) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | | | | | 732 | | | | | | 1,995 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | | | | | (108) | | | | | | (127) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | | | | | (21,725) | | | | | | (23,216) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | | | | | 649 | | | | | | 1,041 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | | | | | (90) | | | | | | (1,719) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | | | | | (21,166) | | | | | | (23,894) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | | | | | (142) | | | | | | 44 | | |
本年度净亏损
|
| | | | (71,241) | | | | | | (99,873) | | | | | | (21,308) | | | | | | (23,850) | | |
其他综合损益: | | | | | | | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | | | | | 36 | | | | | | 48 | | |
本年度综合亏损总额
|
| | | | (71,175) | | | | | | (99,841) | | | | | | (21,272) | | | | | | (23,802) | | |
每股净亏损(基本和稀释后)
|
| | | | (98.05) | | | | | | (137.45) | | | | | | (29.32) | | | | | | (32.48) | | |
|
| | |
截至12月31日
|
| |
截至3月31日
|
| ||||||||||||
| | |
2018
|
| |
2019
|
| |
2020
|
| |||||||||
(单位:千欧元)
|
| | | | |
(未审核)
|
| ||||||||||||
财务状况数据报表: | | | | | | | | | | | | | | | | | | | |
现金和现金等价物
|
| | | | 21,380 | | | | | | 30,684 | | | | | | 43,474 | | |
总资产
|
| | | | 125,659 | | | | | | 130,620 | | | | | | 155,656 | | |
总负债
|
| | | | 93,576 | | | | | | 173,422 | | | | | | 199,313 | | |
总股本
|
| | | | 32,083 | | | | | | (42,802) | | | | | | (43,657) | | |
| | |
截至的三个月
3月31日 |
| |||||||||
(单位为千欧元,每股数据除外)
|
| |
2019
|
| |
2020
|
| ||||||
| | |
(未审核)
|
| |||||||||
营业报表和全面收益(亏损)数据: | | | | | | | | | | | | | |
收入
|
| | | | 3,156 | | | | | | 3,119 | | |
销售成本
|
| | | | (7,558) | | | | | | (5,475) | | |
销售和分销费用
|
| | | | (198) | | | | | | (330) | | |
研发费用
|
| | | | (10,862) | | | | | | (10,902) | | |
一般和行政费用
|
| | | | (6,887) | | | | | | (11,495) | | |
其他营业收入
|
| | | | 732 | | | | | | 1,995 | | |
其他运营费用
|
| | | | (108) | | | | | | (127) | | |
营业亏损
|
| | | | (21,725) | | | | | | (23,216) | | |
财务收入
|
| | | | 649 | | | | | | 1,041 | | |
财务费用
|
| | | | (90) | | | | | | (1,719) | | |
所得税前亏损
|
| | | | (21,166) | | | | | | (23,894) | | |
所得税优惠(费用)
|
| | | | (142) | | | | | | 44 | | |
本年度净亏损
|
| | | | (21,308) | | | | | | (23,850) | | |
其他综合损益: | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | |
外币调整
|
| | | | 36 | | | | | | 48 | | |
本年度综合亏损总额
|
| | | | (21,272) | | | | | | (23,802) | | |
每股净亏损(基本和稀释后)
|
| | | | (29.32) | | | | | | (32.48) | | |
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (2,488) | | | | | | (2,821) | | |
材料
|
| | | | (2,928) | | | | | | (1,550) | | |
第三方服务
|
| | | | (1,489) | | | | | | (675) | | |
维护和租赁
|
| | | | (206) | | | | | | (159) | | |
摊销折旧
|
| | | | (401) | | | | | | (246) | | |
其他
|
| | | | (46) | | | | | | (24) | | |
合计 | | | | | (7,558) | | | | | | (5,475) | | |
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (79) | | | | | | (240) | | |
维护和租赁成本
|
| | | | (88) | | | | | | — | | |
摊销折旧
|
| | | | (19) | | | | | | (41) | | |
其他
|
| | | | (12) | | | | | | (49) | | |
合计 | | | | | (198) | | | | | | (330) | | |
|
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
材料
|
| | | | (963) | | | | | | (1,165) | | |
人员
|
| | | | (3,251) | | | | | | (3,686) | | |
摊销折旧
|
| | | | (129) | | | | | | (351) | | |
注册合法权利的专利和费用
|
| | | | (1,202) | | | | | | (823) | | |
第三方服务
|
| | | | (5,094) | | | | | | (4,263) | | |
维护和租赁
|
| | | | (111) | | | | | | (454) | | |
其他
|
| | | | (112) | | | | | | (160) | | |
合计 | | | | | (10,862) | | | | | | (10,902) | | |
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
重点项目(CV8102、CV7202和SARS-CoV-2) | | | | | | | | | | | | | |
CV8102
|
| | | | 1,125 | | | | | | 1,425 | | |
CV7202
|
| | | | 527 | | | | | | 898 | | |
SARS-CoV-2
|
| | | | — | | | | | | 396 | | |
其他研发项目
|
| | | | 3,535 | | | | | | 2,836 | | |
未分配成本(1)
|
| | | | 5,675 | | | | | | 5,347 | | |
合计 | | | | | 10,862 | | | | | | 10,902 | | |
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
人员
|
| | | | (3,936) | | | | | | (7,055) | | |
维护和租赁成本
|
| | | | (990) | | | | | | (1,333) | | |
第三方服务
|
| | | | (571) | | | | | | (1,420) | | |
法律和其他专业服务
|
| | | | (154) | | | | | | (427) | | |
摊销折旧
|
| | | | (426) | | | | | | (418) | | |
其他
|
| | | | (810) | | | | | | (842) | | |
合计 | | | | | (6,887) | | | | | | (11,495) | | |
| | |
截至的年度
12月31日 |
| |||||||||
(单位为千欧元,每股数据除外)
|
| |
2018
|
| |
2019
|
| ||||||
营业报表和全面收益(亏损)数据: | | | | | | | | | | | | | |
收入
|
| | | | 12,871 | | | | | | 17,416 | | |
销售成本
|
| | | | (17,744) | | | | | | (27,983) | | |
销售和分销费用
|
| | | | (1,085) | | | | | | (1,755) | | |
研发费用
|
| | | | (41,722) | | | | | | (43,242) | | |
一般和行政费用
|
| | | | (25,289) | | | | | | (48,969) | | |
其他营业收入
|
| | | | 808 | | | | | | 5,587 | | |
其他运营费用
|
| | | | (663) | | | | | | (552) | | |
营业亏损
|
| | | | (72,824) | | | | | | (99,498) | | |
财务收入
|
| | | | 1,968 | | | | | | 833 | | |
财务费用
|
| | | | (275) | | | | | | (1,460) | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
所得税优惠(费用)
|
| | | | (110) | | | | | | 252 | | |
本年度净亏损
|
| | | | (71,241) | | | | | | (99,873) | | |
其他综合损益: | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | |
外币调整
|
| | | | 66 | | | | | | 32 | | |
本年度综合亏损总额
|
| | | | (71,175) | | | | | | (99,841) | | |
每股净亏损(基本和稀释后)
|
| | | | (98.05) | | | | | | (137.45) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (7,703) | | | | | | (9,855) | | |
材料
|
| | | | (4,941) | | | | | | (7,542) | | |
第三方服务
|
| | | | (2,340) | | | | | | (7,268) | | |
维护和租赁
|
| | | | (1,758) | | | | | | (1,060) | | |
摊销折旧
|
| | | | (893) | | | | | | (2,038) | | |
其他
|
| | | | (109) | | | | | | (220) | | |
合计 | | | | | (17,744) | | | | | | (27,983) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (581) | | | | | | (1,263) | | |
维护和租赁成本
|
| | | | (300) | | | | | | (167) | | |
摊销折旧
|
| | | | (95) | | | | | | (81) | | |
其他
|
| | | | (109) | | | | | | (243) | | |
合计 | | | | | (1,085) | | | | | | (1,755) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
材料
|
| | | | (5,867) | | | | | | (4,015) | | |
人员
|
| | | | (7,565) | | | | | | (14,385) | | |
摊销折旧
|
| | | | (1,143) | | | | | | (474) | | |
注册合法权利的专利和费用
|
| | | | (4,847) | | | | | | (4,551) | | |
第三方服务
|
| | | | (19,921) | | | | | | (18,626) | | |
维护和租赁
|
| | | | (1,156) | | | | | | (670) | | |
其他
|
| | | | (1,223) | | | | | | (521) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
|
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
关键程序(CV8102和CV7202) | | | | | | | | | | | | | |
CV8102
|
| | | | (1,525) | | | | | | (4,511) | | |
CV7202
|
| | | | (1,987) | | | | | | (2,236) | | |
其他研发项目
|
| | | | (14,047) | | | | | | (14,271) | | |
未分配成本(1)
|
| | | | (24,163) | | | | | | (22,224) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
人员
|
| | | | (10,084) | | | | | | (31,645) | | |
维护和租赁成本
|
| | | | (3,239) | | | | | | (4,604) | | |
第三方服务
|
| | | | (4,006) | | | | | | (5,970) | | |
法律和其他专业服务
|
| | | | (4,078) | | | | | | (2,110) | | |
摊销折旧
|
| | | | (1,635) | | | | | | (2,182) | | |
其他
|
| | | | (2,247) | | | | | | (2,458) | | |
合计 | | | | | (25,289) | | | | | | (48,969) | | |
| | |
截至的三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
(单位:千欧元)
(未审核) |
| |||||||||
净现金流来源(用于): | | | | | | | | | | | | | |
经营活动
|
| | | | (22,630) | | | | | | (2,680) | | |
投资活动
|
| | | | 16,723 | | | | | | (3,319) | | |
融资活动
|
| | | | (279) | | | | | | 18,742 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | 36 | | | | | | 47 | | |
整体现金流入(流出)
|
| | | | 15,260 | | | | | | 43,474 | | |
| | |
截至的年度
12月31日 |
| |||||||||
| | |
2018
|
| |
2019
|
| ||||||
| | |
(单位:千欧元)
|
| |||||||||
净现金流来源(用于): | | | | | | | | | | | | | |
经营活动
|
| | | | (74,110) | | | | | | (86,963) | | |
投资活动
|
| | | | (4,264) | | | | | | 28,181 | | |
融资活动
|
| | | | (112) | | | | | | 67,979 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | 213 | | | | | | 107 | | |
整体现金流入(流出)
|
| | | | (78,273) | | | | | | 9,304 | | |
| | |
按期付款
|
| |||||||||||||||||||||||||||||||||||||||
| | |
合计
|
| |
2020
|
| |
2021
|
| |
2022
|
| |
2023
|
| |
2024
|
| |
此后
|
| |||||||||||||||||||||
| | |
(单位:千欧元)
|
| |||||||||||||||||||||||||||||||||||||||
可转换贷款
|
| | | | (83,940)(1) | | | | | | — | | | | | | — | | | | | | (83,940) | | | | | | — | | | | | | — | | | | | | — | | |
租赁负债
|
| | | | (17,121) | | | | | | (2,843) | | | | | | (2,298) | | | | | | (2,298) | | | | | | (2,298) | | | | | | (2,298) | | | | | | (5,086) | | |
合计
|
| | | | (101,061) | | | | | | (2,843) | | | | | | (2,298) | | | | | | (86,238) | | | | | | (2,298) | | | | | | (2,298) | | | | | | (5,086) | | |
至少发生一次事件的患者,n(%)
|
| |
地层1
(n=16) |
| |
第2层
(n=8) |
| |
第三层
(n=2) |
| |
总体
(n=26) |
| ||||||||||||
TEAE
|
| | | | 16 (100.0) | | | | | | 8 (100.0) | | | | | | 2 (100.0) | | | | | | 26 (100.0) | | |
BI1361849和/或与辐射相关的AE
|
| | | | 16 (100.0) | | | | | | 8 (100.0) | | | | | | 2 (100.0) | | | | | | 26 (100.0) | | |
与BI1361849相关的TEAE
|
| | | | 15 (93.8) | | | | | | 8 (100.0) | | | | | | 2 (100.0) | | | | | | 26 (96.2) | | |
与辐射相关的TEAE
|
| | | | 4 (25.0) | | | | | | 1 (12.5) | | | | | | 0 (50.0) | | | | | | 5 (19.2) | | |
严重的TEAE
|
| | | | 7 (43.8) | | | | | | 3 (37.5) | | | | | | 1 (50.0) | | | | | | 11 (42.3) | | |
严重的BI1361849和/或与辐射相关的AE
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
与BI1361849相关
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
与辐射相关的
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
TEAE毒性等级≥3a
|
| | | | 9 (56.3) | | | | | | 4 (50.0) | | | | | | 2 (100.0) | | | | | | 15 (57.7) | | |
BI1361849和/或与辐射相关的AE毒性等级≥3a
|
| | | | 2 (12.5) | | | | | | 1 (12.5) | | | | | | 1 (50.0) | | | | | | 4 (15.4) | | |
与BI1361849相关
|
| | | | 1 (6.3) | | | | | | 1 (12.5) | | | | | | 1 (50.0) | | | | | | 3 (11.5) | | |
与辐射相关的
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
严重的BI1361849和/或与辐射相关的AE毒性等级≥3a
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
与BI1361849相关
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
与辐射相关的
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
TEAE导致停产
|
| | | | 4 (25.0) | | | | | | 0 | | | | | | 0 | | | | | | 4 (15.4) | | |
TEAE毒性等级为≥3,导致停产
|
| | | | 2 (12.5) | | | | | | 0 | | | | | | 0 | | | | | | 2 (7.7) | | |
TEAE导致中断/剂量修改
|
| | | | 4 (25.0) | | | | | | 0 | | | | | | 0 | | | | | | 4 (15.4) | | |
TEAE导致死亡
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
参数
|
| |
个有反应的患者,n(%)[95%置信区间]
|
| |||||||||||||||||||||
| | |
地层1
(n=16) |
| |
第2层
(n=8) |
| |
第三层
(n=2) |
| |
总体
(n=26) |
| ||||||||||||
回复(CR+PR)率
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
| | | | | [0.2-30.2] | | | | | | [0.0-36.9] | | | | | | [0.0-84.2] | | | | | | [0.1-19.6] | | |
最佳总体反应
|
| | | | | | | | | | | | | | | | | | | | | | | | |
CR
|
| | | | 0 | | | | | | 0 | | | | | | 0 | | | | | | 0 | | |
| | | | | [0.0-20.6] | | | | | | [0.0-36.9] | | | | | | [0.0-84.2] | | | | | | [0.0-13.2] | | |
公关
|
| | | | 1 (6.3) | | | | | | 0 | | | | | | 0 | | | | | | 1 (3.8) | | |
| | | | | [0.2-30.2] | | | | | | [0.0-36.9] | | | | | | [0.0-84.2] | | | | | | [0.1-19.6] | | |
标清
|
| | | | 8 (50.0) | | | | | | 3 (37.5) | | | | | | 1 (50.0) | | | | | | 12 (46.2) | | |
| | | | | [24.7-75.3] | | | | | | [8.5-75.5] | | | | | | [1.3-98.7] | | | | | | [26.6-66.6] | | |
PD
|
| | | | 7 (43.8) | | | | | | 4 (50.0) | | | | | | 1(50.0) | | | | | | 12 (46.2) | | |
| | | | | [19.8-70.1] | | | | | | [15.7-84.3] | | | | | | [1.3-98.7] | | | | | | [26.6-66.6] | | |
东北
|
| | | | 0 | | | | | | 1 (12.5) | | | | | | 0 | | | | | | 1 (3.8) | | |
| | | | | [0.0-20.6] | | | | | | [0.3-52.7] | | | | | | [0.0-84.2] | | | | | | [0.1-19.6] | | |
|
![]() |
| |
![]() |
|
位置
|
| |
区域
(近似平方英尺) |
| |||
德国: | | | | | | | |
Tübingen
|
| | | | 189,000 | | |
美因河畔法兰克福
|
| | | | 8,600 | | |
合计
|
| | | | 197,600 | | |
美国: | | | | | | | |
波士顿
|
| | | | 12,900 | | |
合计
|
| | | | 12,900 | | |
合计
|
| | | | 210,500 | | |
|
名称(1)
|
| |
年龄
|
| |
服刑
|
| |
年(
)
哪个术语 过期 |
| |
职位
|
|
| Franz-Werner Haas,LLD,LLM | | |
50
|
| |
2020年6月 - 颁奖典礼
|
| |
2022
|
| | 首席执行官 | |
| 弗洛里安·冯德穆尔贝,博士,MBA | | |
48
|
| |
2015年9月 - 展示
|
| |
2023
|
| | 首席生产官 | |
| Mariola Fotin-Mleczek博士 | | |
53
|
| |
2015年9月 - 展示
|
| |
2023
|
| | 首席技术官 | |
| 皮埃尔·科米拉,B.Sc. | | |
46
|
| |
2016年11月11日 - 展示
|
| |
2021
|
| | 首席财务官 | |
| Bernd Winterhalter,医学博士,博士(2) | | |
61
|
| |
2018年6月 - 展示
|
| |
不是
已定义 |
| | 首席开发官(临时) | |
| Igor Splawski,博士,硕士 | | |
52
|
| |
2020年7月 - 展示
|
| |
2023
|
| | 首席科学官 | |
|
名称
|
| |
年龄
|
| |
服刑
|
| |
年(
)
哪个术语 过期 |
| |
函数
|
|
| Jean Stéphenne男爵,理学硕士,MBA | | |
70
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 董事长兼监事 | |
| 拉尔夫·克莱门斯医学博士 | | |
68
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
| Mathias Hothum博士 | | |
53
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
| 汉斯·克里斯托夫·坦纳(Hans Christoph Tanner)博士 | | |
69
|
| |
2015年8月 - 展示
|
| |
2024
|
| | 监事长 | |
| Friedrich von Bohlen und Halbach博士 | | |
58
|
| |
2015年8月 - 展示
|
| |
2022
|
| | 副董事长兼监事长 | |
| 医学博士蒂莫西·M·赖特 | | |
64
|
| |
2019年6月 - 展示
|
| |
2022
|
| | 监事长 | |
| 克雷格·A·图曼(Craig A.Tooman),MBA | | |
54
|
| |
2019年6月 - 展示
|
| |
2022
|
| | 监事长 | |
| Viola Bronsema博士 | | |
57
|
| |
–
|
| |
2024
|
| | 监事长 | |
名称
|
| |
已修复
薪酬 (€) |
| |
出席人数
费用 (€) |
| |
合计
薪酬 (€) |
| |||||||||
让·斯特芬男爵
|
| | | | 82,500 | | | |
—
|
| | | | 82,500 | | | |||
拉尔夫·克莱门斯
|
| | | | 55,000 | | | | | | 27,500 | | | | | | 82,500 | | |
Mathias Hothum
|
| | | | 55,000 | | | |
—
|
| | | | 55,000 | | | |||
汉斯·克里斯托夫·坦纳
|
| | | | 55,000 | | | | | | 27,500 | | | | | | 82,500 | | |
Friedrich von Bohlen und Halbach
|
| | | | 55,000 | | | |
—
|
| | | | 55,000 | | | |||
英格玛·霍尔(1)
|
| | | | 110,000 | | | |
—
|
| | | | 110,000 | | | |||
蒂莫西·M·赖特
|
| | | | 21,389 | | | |
—
|
| | | | 21,388 | | | |||
克雷格·A·图曼
|
| | | | 21,389 | | | |
—
|
| | | | 21,388 | | |
名称
|
| |
号码
共 个共享 |
| |
百分比
共 个共享 出色的 |
| |
投票
权利 |
| ||||||
让·斯特芬男爵
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
拉尔夫·克莱门斯
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
Mathias Hothum
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
汉斯·克里斯托夫·坦纳
|
| | | | 1,414 | | | | | | 0.20% | | | |
(2)
|
|
Friedrich von Bohlen und Halbach
|
| | | | 1,818 | | | | | | 0.25% | | | |
(3)
|
|
英格玛·霍尔(1)
|
| | | | 8,485 | | | | | | 1.17% | | | |
(4)
|
|
蒂莫西·M·赖特
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
克雷格·A·图曼
|
| |
—
|
| |
—
|
| |
—
|
|
名称
|
| |
数量
选项 |
| |
标题
|
| |
金额
证券 (€) |
| |
练习
价格 (€) |
| |
购买
价格 (€) |
| |
过期
日期 |
| |||||||||||||||
让·斯特芬男爵
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
拉尔夫·克莱门斯
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
Mathias Hothum
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
汉斯·克里斯托夫·坦纳
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
Friedrich von Bohlen und Halbach
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
英格玛·霍尔(1)
|
| | | | 2,776 | | | |
股票期权奖励
|
| | | | 2,776 | | | | | | 1.00 | | | | | | 2,776 | | | | | | 12/31/2021 | | |
蒂莫西·M·赖特
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
克雷格·A·图曼
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
|
名称*
|
| |
工资
(€) |
| |
奖金
(€)(3) |
| |
所有其他
薪酬(4) (€) |
| |
合计
薪酬 (€) |
| ||||||||||||
Daniel L.Menichella(1)(2)
|
| | | | 508,455(3) | | | | | | 206,250 | | | | | | 37,098 | | | | | | 751,803 | | |
弗洛里安·冯·德·穆尔贝
|
| | | | 250,000 | | | | | | 84,375 | | | | | | 25,634 | | | | | | 360,009 | | |
Mariola Fotin-Mleczek
|
| | | | 210,000 | | | | | | 70,875 | | | | | | 12,977 | | | | | | 293,852 | | |
弗朗茨-维尔纳·哈斯
|
| | | | 247,000 | | | | | | 111,150 | | | | | | 25,442 | | | | | | 383,592 | | |
皮埃尔·科米拉(5)
|
| | | | 250,000 | | | | | | 84,375 | | | | | | 146,103 | | | | | | 480,478 | | |
Bernd Winterhalter(6)
|
| |
—
|
| |
—
|
| | | | 333,601 | | | | | | 333,601 | | | ||||||
Voliotis Dimitris Voliotis(7)(2)
|
| | | | 425,208 | | | | | | 168,760 | | | |
—
|
| | | | 593,958 | | | |||
Ulrike Gnad-Vogt(8)
|
| | | | 187,500 | | | | | | 63,281 | | | | | | 9,732 | | | | | | 260,513 | | |
名称*
|
| |
数量
个共享 |
| |
百分比
未偿还股份 |
| |
投票
权利 |
| ||||||
Daniel L.Menichella(1)
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
弗洛里安·冯·德·穆尔贝
|
| | | | 6,162(2) | | | | | | 0.85% | | | |
(3)
|
|
Mariola Fotin-Mleczek
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
弗朗茨-维尔纳·哈斯
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
皮埃尔·科穆拉
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
Bernd Winterhalter(4)
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
迪米特里斯·沃利奥蒂斯
|
| |
—
|
| |
—
|
| |
—
|
| ||||||
Ulrike Gnad-Vogt
|
| |
—
|
| |
—
|
| |
—
|
|
名称*
|
| |
数量
选项 |
| |
标题
|
| |
金额
证券 (€) |
| |
练习
价格 (€) |
| |
购买
价格 (€) |
| |
过期
日期 |
| |||||||||||||||
Daniel Menichella(1)
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
弗洛里安·冯·德·穆尔贝
|
| | | | 2,017 | | | |
股票期权奖励
|
| | | | 2,017 | | | | | | 1.00 | | | | | | 2,017 | | | | | | 12/31/2021 | | |
Mariola Fotin-Mleczek
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
弗朗茨-维尔纳·哈斯
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
皮埃尔·科穆拉
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
Bernd Winterhalter(2)
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
迪米特里斯·沃利奥蒂斯
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |||||||||||||||
Ulrike Gnad-Vogt
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
| |
—
|
|
名称
|
| |
计划
|
| |
vs
分 已批准 |
| |
最大
归属 分 |
| |
从
开始
归属 周期(仅 用于新 参与者) |
| |
授予日期
(日期: 分配 Letter) |
| |
归属
期间 |
| |
VSOP
计划 |
| |
有效
至 |
| |||||||||||||||
弗洛里安·冯·德·穆尔贝
|
| |
vs
|
| | | | 778 | | | | | | 778 | | | | | | | | | | | | 01.01.2009 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗洛里安·冯·德·穆尔贝
|
| |
vs
|
| | | | 3,486 | | | | | | 3,486 | | | | | | | | | | | | 01.01.2011 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗洛里安·冯·德·穆尔贝
|
| |
vs
|
| | | | 736 | | | | | | 736 | | | | | | | | | | | | 01.01.2013 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗洛里安·冯·德·穆尔贝
|
| |
vs
|
| | | | 1,522 | | | | | | 1,522 | | | | | | | | | | | | 01.01.2015 | | | |
12
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗洛里安·冯·德·穆尔贝
|
| |
vs
|
| | | | 6,100 | | | | | | 6,100 | | | | | | | | | | | | 11.12.2015 | | | |
12
|
| |
之前仅限VSOP IPO
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| |
vs
|
| | | | 316 | | | | | | 316 | | | | | | | | | | | | 01.01.2009 | | | |
60
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2013 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2014 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2015 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Mariola Fotin-Mleczek
|
| |
vs
|
| | | | 2,327 | | | | | | 2,327 | | | | | | | | | | | | 01.01.2015 | | | |
12
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| |
vs
|
| | | | 682 | | | | | | 682 | | | | | | | | | | | | 01.07.2011 | | | |
60
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2013 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2014 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| |
vs
|
| | | | 250 | | | | | | 250 | | | | | | | | | | | | 01.01.2015 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
Ulrike Gnad-Vogt
|
| |
vs
|
| | | | 1,961 | | | | | | 1,961 | | | | | | | | | | | | 01.01.2015 | | | |
12
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| |
vs
|
| | | | 1,400 | | | | | | 1,400 | | | | | | | | | | | | 01.06.2012 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| |
vs
|
| | | | 3,600 | | | | | | 3,600 | | | | | | | | | | | | 01.01.2013 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
弗朗茨-维尔纳·哈斯
|
| |
vs
|
| | | | 1,522 | | | | | | 1,522 | | | | | | | | | | | | 01.01.2015 | | | |
12
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
皮埃尔·科穆拉
|
| |
vs
|
| | | | 5,000 | | | | | | 5,000 | | | | | | 01.10.2016 | | | | | | 18.04.2019 | | | |
36
|
| |
之前的VSOP
|
| | | | 31.12.2025 | | |
丹尼尔·梅尼切拉*
|
| |
*
|
| | | | 29,053 | | | | | | 29,053 | | | | | | 08.01.2017 | | | | | | 14.10.2019 | | | |
48
|
| |
*
|
| | | | 08.01.2027 | | |
| | |
股票受益
在公司成立之前拥有 重组和 优惠(3) |
| |
普通股受益
公司生效后拥有 重组和 优惠(3) |
| ||||||||||||||||||||||||
| | | | | | | | | | | | | | |
不锻炼
承销商的 的 选项 |
| |
全面锻炼
承销商的 的 选项 |
| ||||||||||||
股东
|
| |
号码
|
| |
百分比
|
| |
号码
|
| |
百分比
|
| |
百分比
|
| |||||||||||||||
5%股东: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
Dievini Hopp Biotech Holding
GmbH&Co.kg(1) |
| | | | 654,882 | | | | | | 53.6% | | | | | | 87,150,217 | | | | | | 49.5% | | | | | | 49.0% | | |
Kreditanstalt für Wiederaufbau(2)
|
| | | | 224,466 | | | | | | 18.4% | | | | | | 29,871,441 | | | | | | 17.0% | | | | | | 16.8% | | |
葛兰素史克集团有限公司
|
| | | | 112,233 | | | | | | 9.2% | | | | | | 14,935,721 | | | | | | 8.5% | | | | | | 8.4% | | |
| | |
股票受益
在公司成立之前拥有 重组和 优惠(3) |
| |
普通股受益
公司生效后拥有 重组和 优惠(3) |
| ||||||||||||||||||||||||
| | | | | | | | | | | | | | |
不锻炼
承销商的 的 选项 |
| |
全面锻炼
承销商的 的 选项 |
| ||||||||||||
股东
|
| |
号码
|
| |
百分比
|
| |
号码
|
| |
百分比
|
| |
百分比
|
| |||||||||||||||
管理董事: | | | | | | | |||||||||||||||||||||||||
弗洛里安·冯德穆尔贝,博士,MBA
|
| | | | 9,441 | | | | | | *% | | | | | | 1,256,414 | | | | | | *% | | | | | | *% | | |
Mariola Fotin-Mleczek博士
|
| | | | 339 | | | | | | *% | | | | | | 45,153 | | | | | | *% | | | | | | *% | | |
Franz-Werner Haas,LLD,LLM
|
| | | | 652 | | | | | | *% | | | | | | 86,793 | | | | | | *% | | | | | | *% | | |
皮埃尔·科米拉,B.Sc.
|
| | | | 500 | | | | | | *% | | | | | | 66,539 | | | | | | *% | | | | | | *% | | |
监事长: | | | | | | | |||||||||||||||||||||||||
拉尔夫·克莱门斯医学博士
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
Mathias Hothum博士
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
Jean Stéphenne男爵,理学硕士,MBA
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
汉斯·克里斯托夫·坦纳(Hans Cristoph Tanner)博士
|
| | | | 1,414 | | | | | | *% | | | | | | 188,172 | | | | | | *% | | | | | | *% | | |
Friedrich von Bohlen und Halbach博士
|
| | | | 1,818 | | | | | | *% | | | | | | 241,935 | | | | | | *% | | | | | | *% | | |
医学博士蒂莫西·M·赖特
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
克雷格·A·图曼(Craig A.Tooman),MBA
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
Viola Bronsema,Ph.D.
|
| | | | — | | | | | | —% | | | | | | — | | | | | | —% | | | | | | —% | | |
全体常务董事和监事长合计:
|
| | | | 14,165 | | | | | | 1.2% | | | | | | 1,885,007 | | | | | | 1.1% | | | | | | 1.1% | | |
承销商
|
| |
号码
共 个共享 |
| |||
美国银行证券公司
|
| | | | 5,066,669 | | |
Jefferies LLC
|
| | | | 4,666,666 | | |
瑞士信贷证券(美国)有限责任公司
|
| | | | 2,666,666 | | |
Berenberg Capital Markets LLC
|
| | | | 466,666 | | |
Kempen&Co U.S.A.,Inc.
|
| | | | 466,666 | | |
合计
|
| | | | 13,333,333 | | |
| | |
每股
|
| |
不带选项
|
| |
带选项
|
| |||||||||
公开发行价
|
| | | $ | 16.00 | | | | | $ | 213,333,328 | | | | | $ | 245,333,312 | | |
承保折扣
|
| | | $ | 1.12 | | | | | $ | 14,933,333 | | | | | $ | 17,173,332 | | |
未扣除费用的收益给我们
|
| | | $ | 14.88 | | | | | $ | 198,339,995 | | | | | $ | 228,159,980 | | |
费用
|
| |
金额
|
| |||
美国证券交易委员会注册费
|
| | | $ | 31,844 | | |
纳斯达克上市费
|
| | | | 295,000 | | |
FINRA申请费
|
| | | | 37,950 | | |
印刷费和雕刻费
|
| | | | 300,000 | | |
律师费和开支
|
| | | | 2,000,000 | | |
会计费和费用
|
| | | | 881,273 | | |
杂项成本
|
| | | | 69,350 | | |
合计
|
| | | $ | 3,615,417 | | |
|
中期精简合并经营报表和其他全面收益(亏损)
截至2019年3月31日和2020年3月31日的三个月 |
| | | | F-2 | | |
|
截至2019年12月31日和2020年3月31日的中期简明合并财务状况表
|
| | | | F-3 | | |
|
截至2019年3月31日和2020年3月31日的三个月的中期简明合并股东权益变动表
|
| | | | F-4 | | |
|
截至2019年3月31日的三个月中期简明合并现金流量表
和2020年 |
| | | | F-5 | | |
|
截至2019年3月31日和2020年3月31日的三个月未经审计中期简明合并财务报表附注
|
| | | | F-6 | | |
|
独立注册会计师事务所报告
|
| | | | F-15 | | |
|
截至2018年12月31日和2019年12月31日的两个年度的合并经营报表和其他全面收益(亏损)
|
| | | | F-16 | | |
|
截至2018年12月31日和2019年12月31日的合并财务状况报表
|
| | | | F-17 | | |
|
截至2018年12月31日和2019年12月31日止年度股东权益变动合并报表
|
| | | | F-18 | | |
|
截至2018年12月31日和2019年12月31日止年度合并现金流量表
|
| | | | F-19 | | |
|
截至2018年12月31日和2019年12月31日止三个年度合并财务报表附注
|
| | | | F-20 | | |
| | | | | | | | |
截至3月31日的三个月
|
| |||||||||
| | |
备注
|
| |
2019
|
| |
2020
|
| |||||||||
(单位为千欧元,每股数据除外)
|
| | | | | | | |
(未审核)
|
| |||||||||
收入
|
| | | | | | | | | | 3,156 | | | | | | 3,119 | | |
销售成本
|
| | | | 3.2 | | | | | | (7,558) | | | | | | (5,475) | | |
销售和分销费用
|
| | | | 3.3 | | | | | | (198) | | | | | | (330) | | |
研发费用
|
| | | | 3.4 | | | | | | (10,862) | | | | | | (10,902) | | |
一般和行政费用
|
| | | | 3.5 | | | | | | (6,887) | | | | | | (11,495) | | |
其他营业收入
|
| | | | 3.6 | | | | | | 732 | | | | | | 1,995 | | |
其他运营费用
|
| | | | | | | | | | (108) | | | | | | (127) | | |
营业亏损
|
| | | | | | | | | | (21,725) | | | | | | (23,216) | | |
财务收入
|
| | | | | | | | | | 649 | | | | | | 1,041 | | |
财务费用
|
| | | | | | | | | | (90) | | | | | | (1,719) | | |
所得税前亏损
|
| | | | | | | | | | (21,166) | | | | | | (23,894) | | |
所得税优惠/(费用)
|
| | | | | | | | | | (142) | | | | | | 44 | | |
该期间的净亏损
|
| | | | | | | | | | (21,308) | | | | | | (23,850) | | |
其他综合收益:
|
| | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目
|
| | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | | | | | | | 36 | | | | | | 48 | | |
本期综合亏损总额
|
| | | | | | | | | | (21,272) | | | | | | (23,802) | | |
每股净亏损(基本和稀释后)
|
| | | | | | | | | | (29.32) | | | | | | (32.48) | | |
| | | | | | | | |
截至
|
| |||||||||
| | |
备注
|
| |
12月31日
2019 |
| |
3月31日
2020 |
| |||||||||
(千欧元)
|
| | | | | | | | | | | | | |
(未审核)
|
| |||
资产 | | | | | | | | | | | | | | | | | | | |
非流动资产
|
| | | | | | | | | | | | | | | | | | |
无形资产
|
| | | | | | | | | | 5,698 | | | | | | 6,120 | | |
物业、厂房和设备
|
| | | | 6.1 | | | | | | 48,075 | | | | | | 50,356 | | |
使用权资产
|
| | | | 8 | | | | | | 13,611 | | | | | | 36,876 | | |
其他资产
|
| | | | 6.2 | | | | | | 6,061 | | | | | | 2,027 | | |
递延税金资产
|
| | | | | | | | | | — | | | | | | 169 | | |
非流动资产合计
|
| | | | | | | | | | 73,445 | | | | | | 95,548 | | |
流动资产
|
| | | | | | | | | | | | | | | | | | |
库存
|
| | | | 9 | | | | | | 6,197 | | | | | | 5,425 | | |
贸易应收账款
|
| | | | 3 | | | | | | 15,690 | | | | | | 2,410 | | |
合同资产
|
| | | | 3 | | | | | | 1,463 | | | | | | 2,422 | | |
其他金融资产
|
| | | | 10 | | | | | | 1,458 | | | | | | 1,418 | | |
预付费用和其他资产
|
| | | | 7 | | | | | | 1,683 | | | | | | 4,959 | | |
现金和现金等价物
|
| | | | | | | | | | 30,684 | | | | | | 43,474 | | |
流动资产总额
|
| | | | | | | | | | 57,175 | | | | | | 60,108 | | |
总资产
|
| | | | | | | | | | 130,620 | | | | | | 155,656 | | |
股权和负债
|
| | | | | | | | | | | | | | | | | | |
股权 | | | | | | | | | | | | | | | | | | | |
已发行资本
|
| | | | 4 | | | | | | 727 | | | | | | 743 | | |
资本公积
|
| | | | 4, 5 | | | | | | 472,396 | | | | | | 495,327 | | |
累计亏损
|
| | | | | | | | | | (515,947) | | | | | | (539,797) | | |
其他综合收益
|
| | | | | | | | | | 22 | | | | | | 70 | | |
总股本
|
| | | | | | | | | | (42,802) | | | | | | (43,657) | | |
非流动负债
|
| | | | | | | | | | | | | | | | | | |
可转换贷款
|
| | | | 11 | | | | | | 65,018 | | | | | | 67,078 | | |
租赁负债
|
| | | | 8 | | | | | | 12,126 | | | | | | 29,320 | | |
合同责任
|
| | | | 3 | | | | | | 66,040 | | | | | | 64,002 | | |
递延纳税义务
|
| | | | | | | | | | 1,623 | | | | | | 1,636 | | |
其他负债
|
| | | | | | | | | | 529 | | | | | | 784 | | |
非流动负债合计
|
| | | | | | | | | | 145,336 | | | | | | 162,820 | | |
流动负债
|
| | | | | | | | | | | | | | | | | | |
租赁负债
|
| | | | 8 | | | | | | 2,004 | | | | | | 3,088 | | |
贸易和其他应付款
|
| | | | | | | | | | 6,475 | | | | | | 6,078 | | |
其他负债
|
| | | | 3.6 | | | | | | 12,015 | | | | | | 19,453 | | |
应付所得税
|
| | | | 12 | | | | | | 111 | | | | | | 226 | | |
合同责任
|
| | | | 3 | | | | | | 7,481 | | | | | | 7,648 | | |
流动负债总额
|
| | | | | | | | | | 28,086 | | | | | | 36,493 | | |
总负债
|
| | | | | | | | | | 173,422 | | | | | | 199,313 | | |
总权益和负债
|
| | | | | | | | | | 130,620 | | | | | | 155,656 | | |
(千欧元)
|
| |
已发布
大写 |
| |
大写
预订 |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
总股本
|
| |||||||||||||||
截至2020年1月1日的余额
|
| | | | 727 | | | | | | 472,396 | | | | | | (515,947) | | | | | | 22 | | | | | | (42,802) | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (23,850) | | | | | | — | | | | | | (23,850) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | 48 | | | | | | 48 | | |
综合收益(亏损)合计
|
| | | | — | | | | | | — | | | | | | (23,850) | | | | | | 48 | | | | | | (23,802) | | |
股份支付费用
|
| | | | — | | | | | | 2,947 | | | | | | — | | | | | | — | | | | | | 2,947 | | |
发行股本
|
| | | | 16 | | | | | | 19,984 | | | | | | — | | | | | | — | | | | | | 20,000 | | |
截至2020年3月31日的余额(未经审计)
|
| | | | 743 | | | | | | 495,327 | | | | | | (539,797) | | | | | | 70 | | | | | | (43,657) | | |
|
(千欧元)
|
| |
已发布
大写 |
| |
大写
预订 |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
总股本
|
|
截至2019年1月1日的余额
|
| |
727
|
| |
447,440
|
| |
(416,074)
|
| |
(10)
|
| |
32,083
|
|
净亏损
|
| |
—
|
| |
—
|
| |
(21,308)
|
| |
—
|
| |
(21,308)
|
|
其他综合收益(亏损)
|
| |
—
|
| |
—
|
| |
—
|
| |
36
|
| |
36
|
|
综合收益(亏损)合计
|
| |
—
|
| |
—
|
| |
(21,308)
|
| |
36
|
| |
(21,272)
|
|
截至2019年3月31日的余额(未经审计)
|
| |
727
|
| |
447,440
|
| |
(437,382)
|
| |
26
|
| |
10,811
|
|
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
(千欧元)
|
| |
(未审核)
|
| |||||||||
经营活动
|
| | | | | | | | | | | | |
所得税前亏损
|
| | |
|
(21,308)
|
| | | |
|
(23,850)
|
| |
调整税前亏损至净现金流
|
| | | | | | | | | | | | |
财务收入
|
| | | | (649) | | | | | | (1,041) | | |
财务费用
|
| | | | 90 | | | | | | 1,719 | | |
折旧摊销
|
| | | | 1,561 | | | | | | 1,831 | | |
股份支付费用
|
| | | | — | | | | | | 2,947 | | |
营运资金变动
|
| | | | | | | | | | | | |
贸易应收账款和合同资产减少/(增加)
|
| | | | 3,476 | | | | | | 13,201 | | |
库存减少/(增加)
|
| | | | (1,401) | | | | | | 772 | | |
其他资产减少/(增加)
|
| | | | 129 | | | | | | (3,357) | | |
政府机构和类似机构的赠款收据
|
| | | | 3,477 | | | | | | 11,717 | | |
(减少)/贸易及其他应付款和合同负债增加
|
| | | | (8,208) | | | | | | (6,430) | | |
(减少)/增加其他流动财务和其他负债
|
| | | | 417 | | | | | | 99 | | |
已支付利息
|
| | | | (214) | | | | | | (288) | | |
经营活动使用的净现金流量
|
| | | | (22,630) | | | | | | (2,680) | | |
投资活动
|
| | | | | | | | | | | | |
购置房产、厂房和设备
|
| | | | (1,956) | | | | | | (4,490) | | |
购买无形资产
|
| | | | (290) | | | | | | (776) | | |
资产相关赠款收益
|
| | | | — | | | | | | 1,907 | | |
出售其他金融资产的收益
|
| | | | 18,971 | | | | | | 40 | | |
投资活动提供(用于)的净现金流
|
| | | | 16,723 | | | | | | (3,319) | | |
融资活动
|
| | | | | | | | | | | | |
股权相关交易成本
|
| | | | — | | | | | | (626) | | |
租赁义务付款
|
| | | | (279) | | | | | | (632) | | |
发行股本所得
|
| | | | — | | | | | | 20,000 | | |
融资活动提供(用于)的净现金流
|
| | | | (279) | | | | | | 18,742 | | |
现金和现金等价物的货币换算收益(亏损)
|
| | | | 36 | | | | | | 47 | | |
现金和现金等价物增加(减少)
|
| | | | (6,156) | | | | | | 12,743 | | |
期初现金和现金等价物
|
| | | | 21,380 | | | | | | 30,684 | | |
现金和现金等价物,期末
|
| | | | 15,260 | | | | | | 43,474 | | |
| | |
截止三个月
3月31日 |
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
美国 | | | | | | | | | | | | | |
礼来公司
|
| | | | 2,592 | | | | | | 1,993 | | |
德国 | | | | | | | | | | | | | |
勃林格-英格尔海姆
|
| | | | 467 | | | | | | 482 | | |
瑞士 | | | | | | | | | | | | | |
CRISPR
|
| | | | 97 | | | | | | 78 | | |
荷兰 | | | | | | | | | | | | | |
Genmab
|
| | | | — | | | | | | 566 | | |
合计 | | | | | 3,156 | | | | | | 3,119 | | |
| | |
预付款
|
| |
预付款
包含在 中 合同责任为 2019年3月31日 |
| |
预付款
包含在 中 合同责任为 2020年3月31日 |
| |
确认的收入
预付款 |
| |||||||||||||||
| | |
2020年3月31日
|
| |
2019年3月31日
|
| |
2020年3月31日
|
| ||||||||||||||||||
客户
|
| |
(千)
|
| |
(欧元k)
|
| |
(欧元k)
|
| |
(欧元k)
|
| |||||||||||||||
礼来公司
|
| | 5万美元(42,200欧元)* | | | | | 37,492 | | | | | | 33,975 | | | | | | 879 | | | | | | 879 | | |
CRISPR
|
| | 3000美元(2524欧元)* | | | | | 2,091 | | | | | | 1,782 | | | | | | 77 | | | | | | 77 | | |
勃林格-英格尔海姆
|
| | 3万欧元 | | | | | 17,312 | | | | | | 15,403 | | | | | | 509 | | | | | | 467 | | |
Genmab
|
| | 1万美元(8937欧元)* | | | | | — | | | | | | 8,490 | | | | | | — | | | | | | 447 | | |
合计 | | | | | | | | 56,895 | | | | | | 59,650 | | | | | | 1,465 | | | | | | 1,870 | | |
| | |
12月31日
2019 |
| |
3月31日
2020 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
贸易应收账款
|
| | | | 15,690 | | | | | | 2,410 | | |
合同资产
|
| | | | 1,463 | | | | | | 2,422 | | |
合同责任
|
| | | | 73,521 | | | | | | 71,650 | | |
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (2,488) | | | | | | (2,821) | | |
材料
|
| | | | (2,928) | | | | | | (1,550) | | |
第三方服务
|
| | | | (1,489) | | | | | | (675) | | |
维护和租赁
|
| | | | (206) | | | | | | (159) | | |
摊销折旧
|
| | | | (401) | | | | | | (246) | | |
其他
|
| | | | (46) | | | | | | (24) | | |
合计 | | | | | (7,558) | | | | | | (5,475) | | |
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (79) | | | | | | (240) | | |
维护和租赁
|
| | | | (88) | | | | | | — | | |
摊销折旧
|
| | | | (19) | | | | | | (41) | | |
其他
|
| | | | (12) | | | | | | (49) | | |
合计 | | | | | (198) | | | | | | (330) | | |
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
材料
|
| | | | (963) | | | | | | (1,165) | | |
人员
|
| | | | (3,251) | | | | | | (3,686) | | |
摊销折旧
|
| | | | (129) | | | | | | (351) | | |
注册合法权利的专利和费用
|
| | | | (1,202) | | | | | | (823) | | |
第三方服务
|
| | | | (5,094) | | | | | | (4,263) | | |
维护和租赁
|
| | | | (111) | | | | | | (454) | | |
其他
|
| | | | (112) | | | | | | (160) | | |
合计 | | | | | (10,862) | | | | | | (10,902) | | |
|
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (3,936) | | | | | | (7,055) | | |
维护和租赁
|
| | | | (990) | | | | | | (1,333) | | |
第三方服务
|
| | | | (571) | | | | | | (1,420) | | |
法律和其他专业服务
|
| | | | (154) | | | | | | (427) | | |
摊销折旧
|
| | | | (426) | | | | | | (418) | | |
其他
|
| | | | (810) | | | | | | (842) | | |
合计 | | | | | (6,887) | | | | | | (11,495) | | |
| | |
截至3月31日的三个月
|
| |||||||||
| | |
2019
|
| |
2020
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
政府机构和类似机构提供的补助金和其他费用报销
|
| | | | 531 | | | | | | 1,623 | | |
其他
|
| | | | 201 | | | | | | 372 | | |
合计 | | | | | 732 | | | | | | 1,995 | | |
系列
|
| |
截至
的股票数量
2019年12月31日 |
| |
截至
的股票数量
2020年3月31日 |
| ||||||
A
|
| | | | 23,400 | | | | | | 23,400 | | |
B
|
| | | | 688,692 | | | | | | 705,037 | | |
C
|
| | | | 14,500 | | | | | | 14,500 | | |
合计 | | | | | 726,592 | | | | | | 742,937 | | |
|
/s/Elia Napolitano博士
Wirtschaftsprüfer (德国公共审计师) |
| |
/s/Steffen Maurer
Wirtschaftsprüfer (德国公共审计师) |
|
| | | | | | | | |
截至2013年12月31日的年度
|
| |||||||||
(单位为千欧元,每股数据除外)
|
| |
备注
|
| |
2018
|
| |
2019
|
| |||||||||
收入
|
| | | | 3.1 | | | | | | 12,871 | | | | | | 17,416 | | |
销售成本
|
| | | | 3.2 | | | | | | (17,744) | | | | | | (27,983) | | |
销售和分销费用
|
| | | | 3.3 | | | | | | (1,085) | | | | | | (1,755) | | |
研发费用
|
| | | | 3.4 | | | | | | (41,722) | | | | | | (43,242) | | |
一般和行政费用
|
| | | | 3.5 | | | | | | (25,289) | | | | | | (48,969) | | |
其他营业收入
|
| | | | 3.6 | | | | | | 808 | | | | | | 5,587 | | |
其他运营费用
|
| | | | 3.7 | | | | | | (663) | | | | | | (552) | | |
营业亏损
|
| | | | | | | | | | (72,824) | | | | | | (99,498) | | |
财务收入
|
| | | | | | | | | | 1,968 | | | | | | 833 | | |
财务费用
|
| | | | | | | | | | (275) | | | | | | (1,460) | | |
所得税前亏损
|
| | | | | | | | | | (71,131) | | | | | | (100,125) | | |
所得税优惠/(费用)
|
| | | | 14 | | | | | | (110) | | | | | | 252 | | |
本年度净亏损
|
| | | | | | | | | | (71,241) | | | | | | (99,873) | | |
其他综合收益 | | | | | | | | | | | | | | | | | | | |
随后可能重新分类为损益的项目 | | | | | | | | | | | | | | | | | | | |
外币调整
|
| | | | | | | | | | 66 | | | | | | 32 | | |
本年度综合亏损总额
|
| | | | | | | | | | (71,175) | | | | | | (99,841) | | |
每股净亏损(基本和稀释后)
|
| | | | | | | | | | (98.05) | | | | | | (137.45) | | |
| | | | | | | | |
12月31日
|
| |||||||||
(千欧元)
|
| |
备注
|
| |
2018
|
| |
2019
|
| |||||||||
资产 | | | | | | | | | | | | | | | | | | | |
非流动资产 | | | | | | | | | | | | | | | | | | | |
无形资产
|
| | | | 4 | | | | | | 6,213 | | | | | | 5,698 | | |
物业、厂房和设备
|
| | | | 4 | | | | | | 40,472 | | | | | | 48,075 | | |
其他资产
|
| | | | 4 | | | | | | 5,771 | | | | | | 6,061 | | |
使用权资产
|
| | | | 2 | | | | | | — | | | | | | 13,611 | | |
递延税金资产
|
| | | | 14 | | | | | | 133 | | | | | | — | | |
非流动资产合计
|
| | | | | | | | | | 52,589 | | | | | | 73,445 | | |
流动资产 | | | | | | | | | | | | | | | | | | | |
库存
|
| | | | 5 | | | | | | 2,951 | | | | | | 6,197 | | |
贸易应收账款
|
| | | | 3 | | | | | | 5,476 | | | | | | 15,690 | | |
合同资产
|
| | | | 3 | | | | | | 1,382 | | | | | | 1,463 | | |
其他金融资产
|
| | | | 6 | | | | | | 39,253 | | | | | | 1,458 | | |
预付费用和其他资产
|
| | | | 7 | | | | | | 2,628 | | | | | | 1,683 | | |
现金和现金等价物
|
| | | | | | | | | | 21,380 | | | | | | 30,684 | | |
流动资产总额
|
| | | | | | | | | | 73,070 | | | | | | 57,175 | | |
总资产
|
| | | | | | | | | | 125,659 | | | | | | 130,620 | | |
股权和负债 | | | | | | | | | | | | | | | | | | | |
股权 | | | | | | | | | | | | | | | | | | | |
已发行资本
|
| | | | | | | | | | 727 | | | | | | 727 | | |
资本公积
|
| | | | | | | | | | 447,440 | | | | | | 472,396 | | |
累计亏损
|
| | | | | | | | | | (416,074) | | | | | | (515,947) | | |
其他综合收益
|
| | | | | | | | | | (10) | | | | | | 22 | | |
总股本
|
| | | | 8 | | | | | | 32,083 | | | | | | (42,802) | | |
非流动负债 | | | | | | | | | | | | | | | | | | | |
可转换贷款
|
| | | | 12 | | | | | | — | | | | | | 65,018 | | |
租赁负债
|
| | | | 2 | | | | | | — | | | | | | 12,126 | | |
合同责任
|
| | | | 3 | | | | | | 64,583 | | | | | | 66,040 | | |
递延纳税义务
|
| | | | 13 | | | | | | — | | | | | | 1,623 | | |
其他负债
|
| | | | | | | | | | 863 | | | | | | 529 | | |
非流动负债合计
|
| | | | | | | | | | 65,446 | | | | | | 145,336 | | |
流动负债 | | | | | | | | | | | | | | | | | | | |
其他金融负债
|
| | | | | | | | | | 77 | | | | | | — | | |
租赁负债
|
| | | | 2 | | | | | | — | | | | | | 2,004 | | |
贸易和其他应付款
|
| | | | 11 | | | | | | 10,913 | | | | | | 6,475 | | |
其他负债
|
| | | | 12 | | | | | | 11,146 | | | | | | 12,015 | | |
应付所得税
|
| | | | 13 | | | | | | 217 | | | | | | 111 | | |
合同责任
|
| | | | 3 | | | | | | 5,777 | | | | | | 7,481 | | |
流动负债总额
|
| | | | | | | | | | 28,130 | | | | | | 28,086 | | |
总负债
|
| | | | | | | | | | 93,576 | | | | | | 173,422 | | |
总权益和负债
|
| | | | | | | | | | 125,659 | | | | | | 130,620 | | |
(千欧元)
|
| |
已发布
大写 |
| |
大写
预订 |
| |
累计
赤字 |
| |
币种
翻译 预订 |
| |
总股本
|
| |||||||||||||||
截至2018年1月1日的余额
|
| | | | 727 | | | | | | 447,438 | | | | | | (345,320) | | | | | | (76) | | | | | | 102,769 | | |
首次采用IFRS 9的影响
|
| | | | — | | | | | | — | | | | | | (183) | | | | | | — | | | | | | (183) | | |
首次采用IFRS 15的影响
|
| | | | — | | | | | | — | | | | | | 670 | | | | | | — | | | | | | 670 | | |
截至2018年1月1日调整后余额
|
| | | | 727 | | | | | | 447,438 | | | | | | (344,833) | | | | | | (76) | | | | | | 103,256 | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (71,241) | | | | | | — | | | | | | (71,241) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | 66 | | | | | | 66 | | |
综合收益(亏损)合计
|
| | | | — | | | | | | — | | | | | | (71,241) | | | | | | 66 | | | | | | (71,175) | | |
股份支付计划的费用
|
| | | | — | | | | | | 2 | | | | | | — | | | | | | — | | | | | | 2 | | |
截至2018年12月31日的余额
|
| | | | 727 | | | | | | 447,440 | | | | | | (416,074) | | | | | | (10) | | | | | | 32,083 | | |
净亏损
|
| | | | — | | | | | | — | | | | | | (99,873) | | | | | | — | | | | | | (99,873) | | |
其他综合收益(亏损)
|
| | | | — | | | | | | — | | | | | | — | | | | | | 32 | | | | | | 32 | | |
综合收益(亏损)合计
|
| | | | — | | | | | | — | | | | | | (99,873) | | | | | | 32 | | | | | | (99,841) | | |
可转换贷款的权益部分
|
| | | | — | | | | | | 7,604 | | | | | | — | | | | | | — | | | | | | 7,604 | | |
可转换贷款递延税款
|
| | | | — | | | | | | (2,212) | | | | | | — | | | | | | — | | | | | | (2,212) | | |
股份支付计划的费用
|
| | | | — | | | | | | 19,564 | | | | | | — | | | | | | — | | | | | | 19,564 | | |
截至2019年12月31日的余额
|
| | | | 727 | | | | | | 472,396 | | | | | | (515,947) | | | | | | 22 | | | | | | (42,802) | | |
| | |
截至2013年12月31日的年度
|
| |||||||||
(千欧元)
|
| |
2018
|
| |
2019
|
| ||||||
经营活动 | | | | | | | | | | | | | |
所得税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
调整税前亏损至净现金流 | | | | | | | | | | | | | |
财务收入
|
| | | | (1,968) | | | | | | (833) | | |
财务费用
|
| | | | 275 | | | | | | 1,460 | | |
折旧摊销
|
| | | | 3,781 | | | | | | 7,164 | | |
固定资产处置损失
|
| | | | 52 | | | | | | 241 | | |
股份支付费用
|
| | | | (4,248) | | | | | | 19,564 | | |
营运资金变动 | | | | | | | | | | | | | |
贸易应收账款和合同资产减少/(增加)
|
| | | | (5,595) | | | | | | (10,117) | | |
库存减少/(增加)
|
| | | | 878 | | | | | | (3,246) | | |
其他资产减少/(增加)
|
| | | | (6,106) | | | | | | 630 | | |
政府机构和类似机构的赠款收据
|
| | | | 214 | | | | | | 9,304 | | |
(减少)/贸易及其他应付款和合同负债增加
|
| | | | 9,402 | | | | | | (9,584) | | |
(减少)/增加其他流动财务和其他负债
|
| | | | 336 | | | | | | (334) | | |
缴纳所得税
|
| | | | (26) | | | | | | (345) | | |
收到利息
|
| | | | 15 | | | | | | 81 | | |
已支付利息
|
| | | | 11 | | | | | | (824) | | |
净现金流量(用于)经营活动
|
| | | | (74,110) | | | | | | (86,963) | | |
投资活动 | | | | | | | | | | | | | |
购置房产、厂房和设备
|
| | | | (9,406) | | | | | | (11,172) | | |
购买无形资产
|
| | | | (5,317) | | | | | | (1,052) | | |
资产相关赠款收益
|
| | | | — | | | | | | 2,325 | | |
其他金融资产收益
|
| | | | 10,459 | | | | | | 38,080 | | |
投资活动产生(用于)的净现金流
|
| | | | (4,264) | | | | | | 28,181 | | |
融资活动 | | | | | | | | | | | | | |
租赁债务付款
|
| | | | (112) | | | | | | (1,910) | | |
可转换贷款收益
|
| | | | — | | | | | | 69,889 | | |
融资活动产生(用于)的净现金流
|
| | | | (112) | | | | | | 67,979 | | |
现金及现金等价物净增(减)
|
| | | | (78,486) | | | | | | 9,197 | | |
货币换算收益对现金和现金等价物的影响
|
| | | | 213 | | | | | | 107 | | |
期初现金和现金等价物
|
| | | | 99,653 | | | | | | 21,380 | | |
现金和现金等价物,期末
|
| | | | 21,380 | | | | | | 30,684 | | |
|
软件和许可证
|
| |
3到8年
|
|
|
建筑物:
|
| |
1至10年
|
|
|
技术装备和机器:
|
| |
3到14年
|
|
|
其他设备、家具和固定装置:
|
| |
3到14年
|
|
| | |
欧元k
|
| |||
截至2018年12月31日的现有承诺 | | | | | | | |
经营租赁承诺额
|
| | | | 48,008 | | |
融资租赁负债的最低租赁付款(名义金额)
|
| | | | 78 | | |
短期租赁的解除选项
|
| | | | (110) | | |
开始日期在2019年1月1日之后的租约,金额为上述截至2018年12月31日的现有承诺额
|
| | | | (28,557) | | |
其他
|
| | | | 123 | | |
截至2019年1月1日的总租赁负债
|
| | | | 19,542 | | |
打折效果
|
| | | | (3,655) | | |
截至2019年1月1日的租赁负债
|
| | | | 15,887 | | |
截至2018年12月31日融资租赁负债现值
|
| | | | (77) | | |
截至2019年1月1日首次应用IFRS第16号时的租赁负债
|
| | | | 15,810 | | |
截至2019年1月1日的加权平均增量借款利率
|
| | | | 5.64% | | |
|
土地和建筑:
|
| |
1至15年
|
|
|
车辆:
|
| |
3至4年
|
|
|
其他设备:
|
| |
2至5年
|
|
| | |
使用权资产
|
| |||||||||||||||||||||
| | |
土地和
建筑物 |
| |
车辆
|
| |
其他
设备 |
| |
合计
|
| ||||||||||||
| | |
欧元
|
| |
欧元
|
| |
欧元
|
| |
欧元
|
| ||||||||||||
截至2019年1月1日
|
| | | | 15,536 | | | | | | 132 | | | | | | 239 | | | | | | 15,907 | | |
添加
|
| | | | 82 | | | | | | 59 | | | | | | 13 | | | | | | 154 | | |
折旧费
|
| | | | (2,322) | | | | | | (65) | | | | | | (142) | | | | | | (2,529) | | |
外币折算
|
| | | | 79 | | | | | | — | | | | | | — | | | | | | 79 | | |
截至2019年12月31日
|
| | | | 13,375 | | | | | | 126 | | | | | | 110 | | | | | | 13,611 | | |
| | |
欧元k
|
| |||
截至2019年1月1日
|
| | |
|
15,887
|
| |
添加
|
| | | | 153 | | |
利息增值
|
| | | | 824 | | |
付款
|
| | | | (2,812) | | |
外币折算
|
| | | | 78 | | |
截至2019年12月31日
|
| | | | 14,130 | | |
当前
|
| | | | 2,004 | | |
非当前
|
| | | | 12,126 | | |
| | |
欧元k
|
| |||
使用权资产折旧费用
|
| | | | (2,529) | | |
租赁负债利息支出
|
| | | | (824) | | |
与短期租赁相关的费用(包括在销售成本中)
|
| | | | (167) | | |
低价资产租赁相关费用(计入行政费用)
|
| | | | (94) | | |
损益确认总额
|
| | | | (3,614) | | |
| | |
12月31日
2018 |
| |
12月31日
2019 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
美国 | | | | | | | | | | | | | |
礼来公司
|
| | | | 8,927 | | | | | | 14,319 | | |
德国 | | | | | | | | | | | | | |
勃林格-英格尔海姆
|
| | | | 3,337 | | | | | | 2,474 | | |
其他
|
| | | | 5 | | | | | | 104 | | |
瑞士 | | | | | | | | | | | | | |
CRISPR
|
| | | | 602 | | | | | | 519 | | |
合计
|
| | | | 12,871 | | | | | | 17,416 | | |
客户
|
| |
预付款
在 收到或应收 2019年12月31日 (千) |
| |
预付款
包含在 中 合同责任为 2019年12月31日 (欧元k) |
| |
确认的收入
预付款 (欧元k) |
| ||||||||||||
|
2018
|
| |
2019
|
| |||||||||||||||||
礼来公司
|
| |
5万美元(42,200欧元)
|
| | | | 34,854 | | | | | | 3,516 | | | | | | 3,516 | | |
CRISPR
|
| | 3000美元(2524欧元) | | | | | 1,859 | | | | | | 310 | | | | | | 310 | | |
勃林格-英格尔海姆
|
| | 3万欧元 | | | | | 15,870 | | | | | | 2,035 | | | | | | 1,951 | | |
Genmab
|
| | 1万美元(8937欧元) | | | | | 8,937 | | | | | | — | | | | | | — | | |
合计 | | | | | 61,520 | | | | | | 5,861 | | | | | | 5,777 | | |
| | |
1月1日
2018 |
| |
12月31日
2018 |
| |
12月31日
2019 |
| |||||||||
| | |
欧元k
|
| |
欧元k
|
| |
欧元k
|
| |||||||||
贸易应收账款
|
| | | | 463 | | | | | | 5,476 | | | | | | 15,690 | | |
合同资产
|
| | | | — | | | | | | 1,382 | | | | | | 1,463 | | |
合同责任
|
| | | | 69,220 | | | | | | 70,360 | | | | | | 73,521 | | |
| | |
年终
|
| |||||||||
| | |
2018
欧元k |
| |
2019
欧元k |
| ||||||
一年内
|
| | | | 5,777 | | | | | | 7,481 | | |
一年多
|
| | | | 64,583 | | | | | | 66,040 | | |
合计 | | | | | 70,360 | | | | | | 73,521 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (7,703) | | | | | | (9,855) | | |
材料
|
| | | | (4,941) | | | | | | (7,542) | | |
第三方服务
|
| | | | (2,340) | | | | | | (7,268) | | |
维护和租赁
|
| | | | (1,758) | | | | | | (1,060) | | |
摊销折旧
|
| | | | (893) | | | | | | (2,038) | | |
其他
|
| | | | (109) | | | | | | (220) | | |
合计
|
| | | | (17,744) | | | | | | (27,983) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (581) | | | | | | (1,263) | | |
维护和租赁成本
|
| | | | (300) | | | | | | (167) | | |
摊销折旧
|
| | | | (95) | | | | | | (81) | | |
其他
|
| | | | (109) | | | | | | (243) | | |
合计 | | | | | (1,085) | | | | | | (1,755) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
材料
|
| | | | (5,867) | | | | | | (4,015) | | |
人员
|
| | | | (7,565) | | | | | | (14,385) | | |
摊销折旧
|
| | | | (1,143) | | | | | | (474) | | |
注册合法权利的专利和费用
|
| | | | (4,847) | | | | | | (4,551) | | |
第三方服务
|
| | | | (19,921) | | | | | | (18,626) | | |
维护和租赁
|
| | | | (1,156) | | | | | | (670) | | |
其他
|
| | | | (1,223) | | | | | | (521) | | |
合计 | | | | | (41,722) | | | | | | (43,242) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
人员
|
| | | | (10,084) | | | | | | (31,645) | | |
维护和租赁成本
|
| | | | (3,239) | | | | | | (4,604) | | |
第三方服务
|
| | | | (4,006) | | | | | | (5,970) | | |
法律和其他专业服务
|
| | | | (4,078) | | | | | | (2,110) | | |
摊销折旧
|
| | | | (1,635) | | | | | | (2,182) | | |
其他
|
| | | | (2,247) | | | | | | (2,458) | | |
合计 | | | | | (25,289) | | | | | | (48,969) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
政府机构和类似机构提供的补助金和其他费用报销
|
| | | | 808 | | | | | | 5,385 | | |
其他
|
| | | | — | | | | | | 202 | | |
合计
|
| | | | 808 | | | | | | 5,587 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
监事会换届
|
| | | | (343) | | | | | | (521) | | |
其他
|
| | | | (320) | | | | | | (30) | | |
合计
|
| | | | (663) | | | | | | (552) | | |
(千欧元)
|
| |
软件和
许可证 |
| |
前进
付款 |
| |
合计
|
| |||||||||
采购成本 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 3,402 | | | | | | 235 | | | | | | 3,638 | | |
添加
|
| | | | 5,314 | | | | | | 2 | | | | | | 5,317 | | |
截至2018年12月31日
|
| | | | 8,717 | | | | | | 238 | | | | | | 8,954 | | |
累计摊销和减值费用 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,545 | | | | | | — | | | | | | 1,545 | | |
摊销
|
| | | | 1,197 | | | | | | — | | | | | | 1,197 | | |
截至2018年12月31日
|
| | | | 2,742 | | | | | | — | | | | | | 2,742 | | |
|
(千欧元)
|
| |
软件和
许可证 |
| |
前进
付款 |
| |
合计
|
| |||||||||
采购成本 | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 8,717 | | | | | | 238 | | | | | | 8,954 | | |
添加
|
| | | | 738 | | | | | | 44 | | | | | | 782 | | |
处置
|
| | | | (6) | | | | | | — | | | | | | (6) | | |
截至2019年12月31日
|
| | | | 9,449 | | | | | | 282 | | | | | | 9,731 | | |
累计摊销和减值费用 | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 2,742 | | | | | | — | | | | | | 2,742 | | |
摊销
|
| | | | 1,295 | | | | | | — | | | | | | 1,295 | | |
处置
|
| | | | (4) | | | | | | — | | | | | | (4) | | |
截至2019年12月31日
|
| | | | 4,033 | | | | | | — | | | | | | 4,033 | | |
账面金额 | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,858 | | | | | | 235 | | | | | | 2,093 | | |
截至2018年12月31日
|
| | | | 5,975 | | | | | | 238 | | | | | | 6,213 | | |
截至2019年12月31日
|
| | | | 5,416 | | | | | | 282 | | | | | | 5,698 | | |
(千欧元)
|
| |
建筑物
|
| |
技术
设备 和机器 |
| |
其他
设备, 家具 和灯具 |
| |
资产
下的 施工 |
| |
合计
|
| |||||||||||||||
采购成本 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 5,398 | | | | | | 12,230 | | | | | | 4,665 | | | | | | 27,103 | | | | | | 49,397 | | |
添加
|
| | | | 490 | | | | | | 953 | | | | | | 719 | | | | | | 7,244 | | | | | | 9,406 | | |
处置
|
| | | | — | | | | | | (150) | | | | | | (157) | | | | | | — | | | | | | (307) | | |
重新分类
|
| | | | — | | | | | | 1,303 | | | | | | 19 | | | | | | (1,323) | | | | | | — | | |
货币换算
|
| | | | — | | | | | | — | | | | | | — | | | | | | 1 | | | | | | 1 | | |
截至2018年12月31日
|
| | | | 5,888 | | | | | | 14,336 | | | | | | 5,247 | | | | | | 33,025 | | | | | | 58,497 | | |
累计折旧和减值费用 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 1,337 | | | | | | 4,610 | | | | | | 2,654 | | | | | | 7,120 | | | | | | 15,721 | | |
折旧
|
| | | | 371 | | | | | | 1,299 | | | | | | 890 | | | | | | — | | | | | | 2,559 | | |
处置
|
| | | | — | | | | | | (99) | | | | | | (157) | | | | | | — | | | | | | (255) | | |
截至2018年12月31日
|
| | | | 1,708 | | | | | | 5,810 | | | | | | 3,387 | | | | | | 7,120 | | | | | | 18,025 | | |
|
(千欧元)
|
| |
建筑物
|
| |
技术
设备 和机器 |
| |
其他
设备, 家具 和灯具 |
| |
资产
下的 施工 |
| |
合计
|
| |||||||||||||||
采购成本 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 5,888 | | | | | | 14,336 | | | | | | 5,247 | | | | | | 33,025 | | | | | | 58,497 | | |
添加
|
| | | | 854 | | | | | | 2,152 | | | | | | 712 | | | | | | 7,435 | | | | | | 11,152 | | |
处置
|
| | | | (65) | | | | | | (319) | | | | | | (248) | | | | | | — | | | | | | (632) | | |
重新分类
|
| | | | 167 | | | | | | 883 | | | | | | 187 | | | | | | (1,237) | | | | | | — | | |
货币换算
|
| | | | — | | | | | | — | | | | | | 3 | | | | | | 4 | | | | | | 6 | | |
截至2019年12月31日
|
| | | | 6,844 | | | | | | 17,051 | | | | | | 5,902 | | | | | | 39,226 | | | | | | 69,023 | | |
累计折旧和减值费用 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2019年1月1日
|
| | | | 1,708 | | | | | | 5,810 | | | | | | 3,388 | | | | | | 7,120 | | | | | | 18,026 | | |
折旧
|
| | | | 779 | | | | | | 1,637 | | | | | | 899 | | | | | | — | | | | | | 3,315 | | |
处置
|
| | | | (37) | | | | | | (190) | | | | | | (164) | | | | | | — | | | | | | (392) | | |
货币换算
|
| | | | — | | | | | | — | | | | | | 1 | | | | | | — | | | | | | 1 | | |
截至2019年12月31日
|
| | | | 2,449 | | | | | | 7,257 | | | | | | 4,123 | | | | | | 7,120 | | | | | | 20,949 | | |
账面金额 | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
截至2018年1月1日
|
| | | | 4,061 | | | | | | 7,621 | | | | | | 2,011 | | | | | | 19,982 | | | | | | 33,675 | | |
截至2018年12月31日
|
| | | | 4,181 | | | | | | 8,526 | | | | | | 1,860 | | | | | | 25,904 | | | | | | 40,472 | | |
截至2019年12月31日
|
| | | | 4,395 | | | | | | 9,795 | | | | | | 1,779 | | | | | | 32,105 | | | | | | 48,075 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
原材料
|
| | | | 2,742 | | | | | | 6,177 | | |
成品
|
| | | | — | | | | | | 14 | | |
其他
|
| | | | 209 | | | | | | 6 | | |
合计
|
| | | | 2,951 | | | | | | 6,197 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期投资
|
| | | | 39,024 | | | | | | 430 | | |
其他
|
| | | | 229 | | | | | | 1,028 | | |
合计 | | | | | 39,253 | | | | | | 1,458 | | |
|
系列
|
| |
个共享
|
| |||
A
|
| | | | 23,400 | | |
B
|
| | | | 688,692 | | |
C
|
| | | | 14,500 | | |
合计
|
| | | | 726,592 | | |
| | |
2018
|
| |
2019
|
| ||||||
期初未完成
|
| | | | 59,908 | | | | | | 49,899 | | |
期间发放的
|
| | | | — | | | | | | 5,000 | | |
在
期间过期
|
| | | | (10,009) | | | | | | — | | |
期末未清偿
|
| | | | 49,899 | | | | | | 54,899 | | |
其归属(和费用)
|
| | | | 49,899 | | | | | | 54,899 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
研发费用
|
| | | | 4,229 | | | | | | — | | |
一般和行政费用
|
| | | | 21 | | | | | | (6,074) | | |
合计 | | | | | 4,250 | | | | | | (6,074) | | |
|
加权平均公允价值
|
| | | | 欧元 505.48 | | |
|
加权平均股价
|
| | | | 1,223.16欧元 | | |
|
行权价(825.77美元)
|
| | | | 欧元 750.99 | | |
|
预期波动率(%)
|
| | | | 50.0% | | |
|
预期寿命(年)
|
| | | | 1.16 | | |
|
无风险利率(%)
|
| | | | 1.77% | | |
|
期初未完成
|
| | | | — | | |
|
期间发放的
|
| | | | 5,600 | | |
|
期末未清偿
|
| | | | 5,600 | | |
|
其归属
|
| | | | 1,318 | | |
|
已支出
|
| | | | 2,137 | | |
| | |
2019
|
| |||
| | |
欧元k
|
| |||
研发费用
|
| | | | (258) | | |
销售和分销费用
|
| | | | (743) | | |
一般和行政费用
|
| | | | (79) | | |
合计 | | | | | (1,080) | | |
|
加权平均公允价值
|
| | 欧元 514.93 | |
|
加权平均股价
|
| | 1,223.16欧元 | |
|
行权价(1,101.03美元)
|
| | 欧元 998.38 | |
|
预期波动率(%)
|
| | 50.0% | |
|
预期寿命(年)
|
| | 4.77 | |
|
无风险利率(%)
|
| | 1.71% | |
|
期初未完成
|
| | | | — | | |
|
期间发放的
|
| | | | 29,053 | | |
|
期末未清偿
|
| | | | 29,053 | | |
|
其归属
|
| | | | 21,184 | | |
|
已支出
|
| | | | 24,099 | | |
| | |
2019
|
| |||
| | |
欧元k
|
| |||
一般和行政费用
|
| | | | (12,409) | | |
合计 | | | | | (12,409) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
贸易应付款
|
| | | | (9,029) | | | | | | (5,331) | | |
应付许可费
|
| | | | (501) | | | | | | (537) | | |
其他负债
|
| | | | (1,383) | | | | | | (607) | | |
合计 | | | | | (10,913) | | | | | | (6,475) | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
累计奖金
|
| | | | 1,903 | | | | | | 2,477 | | |
累计休假
|
| | | | 682 | | | | | | 780 | | |
未付发票
|
| | | | 6,812 | | | | | | 3,478 | | |
专业费
|
| | | | 292 | | | | | | 578 | | |
来自政府机构和类似机构的赠款
|
| | | | 1,186 | | | | | | 4,148 | | |
其他
|
| | | | 271 | | | | | | 554 | | |
合计 | | | | | 11,146 | | | | | | 12,015 | | |
| | |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
税前亏损
|
| | | | (71,131) | | | | | | (100,125) | | |
预期税收优惠(基于2019年和2018年29.13%的法定税率)
|
| | | | 20,744 | | | | | | 29,162 | | |
对上一年度当期所得税的调整
|
| | | | 42 | | | | | | — | | |
集团税率和地方税率差异的影响
|
| | | | 10 | | | | | | 8 | | |
未确认税损结转的影响
|
| | | | (22,428) | | | | | | (22,836) | | |
无法识别DTA/DTL造成的影响
|
| | | | — | | | | | | — | | |
首次确认税损结转
|
| | | | 430 | | | | | | — | | |
税收方面不可抵扣的费用
|
| | | | | | | | | | | | |
不可抵扣的股份支付对−的影响
|
| | | | 1,209 | | | | | | (5,698) | | |
当地贸易税(加计/扣减)产生的−效应
|
| | | | (65) | | | | | | (191) | | |
−其他不可抵扣费用
|
| | | | (53) | | | | | | (78) | | |
其他效果
|
| | | | — | | | | | | (114) | | |
有效税收优惠/(费用)
|
| | | | (110) | | | | | | 252 | | |
税损结转
|
| |
2018
|
| |
2019
|
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
企业所得税未使用税损
|
| | | | 330,753 | | | | | | 407,434 | | |
贸易税未使用税损
|
| | | | 329,210 | | | | | | 405,123 | | |
2019
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
合计
欧元 |
| |||||||||||||||
可转换贷款
|
| | | | — | | | | | | — | | | | | | (83,940) | | | | | | — | | | | | | (83,940) | | |
租赁负债(附注2)
|
| | | | (732) | | | | | | (1,985) | | | | | | (9,192) | | | | | | (5,086) | | | | | | (16,995) | | |
其他负债
|
| | | | — | | | | | | (12,015) | | | | | | (362) | | | | | | (167) | | | | | | (12,544) | | |
贸易和其他应付款
|
| | | | (5,938) | | | | | | (537) | | | | | | — | | | | | | — | | | | | | (6,475) | | |
合计 | | | | | (6,670) | | | | | | (14,537) | | | | | | (93,494) | | | | | | (5,253) | | | | | | (119,954) | | |
|
2018
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
总计欧元
|
| |||||||||||||||
融资租赁负债
|
| | | | (29) | | | | | | (48) | | | | | | — | | | | | | — | | | | | | (77) | | |
其他负债
|
| | | | — | | | | | | (11,146) | | | | | | (688) | | | | | | (175) | | | | | | (12,009) | | |
贸易和其他应付款
|
| | | | (10,378) | | | | | | (535) | | | | | | — | | | | | | — | | | | | | (10,913) | | |
合计 | | | | | (10,407) | | | | | | (11,729) | | | | | | (688) | | | | | | (175) | | | | | | (22,999) | | |
2018
|
| |
少于
3个半月 欧元 |
| |
3至12个月
欧元 |
| |
1至5年
欧元 |
| |
>5年
欧元 |
| |
总计欧元
|
| |||||||||||||||
经营租赁承诺额
|
| | | | — | | | | | | (84) | | | | | | (91) | | | | | | — | | | | | | (175) | | |
租赁协议
|
| | | | (683) | | | | | | (2,576) | | | | | | (21,160) | | | | | | (23,589) | | | | | | (48,008) | | |
合计 | | | | | (683) | | | | | | (2,660) | | | | | | (21,251) | | | | | | (23,589) | | | | | | (48,183) | | |
| | |
2019
(千) |
| |||
现金和现金等价物
|
| |
22,608欧元
|
| |
25,398美元
|
|
贸易和其他应收账款
|
| |
9458欧元
|
| |
10,585美元
|
|
其他应收账款
|
| |
105欧元
|
| |
93英镑
|
|
| | |
84欧元
|
| |
92瑞士法郎
|
|
| | |
81欧元
|
| |
91美元
|
|
外币货币资产
|
| |
32,336欧元
|
| | | |
贸易和其他应付款
|
| |
505欧元
|
| |
567美元
|
|
| | |
219欧元
|
| |
186英镑
|
|
| | |
10欧元
|
| |
11瑞士法郎
|
|
外币货币负债
|
| |
734欧元
|
| | | |
| | |
2018
(千) |
| |||
现金和现金等价物
|
| |
16941欧元
|
| |
19398美元
|
|
贸易和其他应收账款
|
| |
2059欧元
|
| |
3374美元
|
|
外币货币资产
|
| |
1.9万欧元
|
| |
22,772美元
|
|
贸易和其他应付款
|
| |
8002欧元
|
| |
9162美元
|
|
| | |
132欧元
|
| |
118英镑
|
|
| | |
46欧元
|
| |
51瑞士法郎
|
|
外币货币负债
|
| |
8180欧元
|
| | | |
| 2018年(1欧元=1.1450美元) | | | 2019年(1欧元=1.1234美元) | |
| 10,544k欧元,13,090k美元 | | | 30,656k欧元,34,400k美元 | |
千欧元
|
| |
1月1日
2019 |
| |
现金
流程 |
| |
重新分类
|
| |
新
租约 |
| |
累计
利息 |
| |
外来
交换 移动 |
| |
12月31日
2019 |
| |||||||||||||||||||||
可转换贷款
|
| | | | — | | | | | | 69,889 | | | | | | (7,604) | | | | | | — | | | | | | 2,733 | | | | | | — | | | | | | 65,018 | | |
租赁负债
|
| | | | 15,810 | | | | | | (1,910) | | | | | | — | | | | | | 153 | | | | | | — | | | | | | 77 | | | | | | 14,130 | | |
融资负债总额
活动 |
| | | | 15,810 | | | | | | 67,979 | | | | | | (7,604) | | | | | | 153 | | | | | | 2,733 | | | | | | 77 | | | | | | 79,148 | | |
|
千欧元
|
| |
1月1日
2018 |
| |
更改自
融资 现金流 |
| |
12月31日
2018 |
| |||||||||
租赁负债
|
| | | | 188 | | | | | | (112) | | | | | | 77 | | |
融资活动的总负债
|
| | | | 188 | | | | | | (112) | | | | | | 77 | | |
2019年密钥管理薪酬
|
| |
管理
板 |
| |
监管
板 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期效益
|
| | | | 3,166 | | | | | | 521 | | |
股份支付
|
| | | | 18,483 | | | | | | — | | |
合计 | | | | | 21,649 | | | | | | 521 | | |
2018年密钥管理薪酬
|
| |
管理
板 |
| |
监管
板 |
| ||||||
| | |
欧元k
|
| |
欧元k
|
| ||||||
短期效益
|
| | | | 2,195 | | | | | | 343 | | |
合计 | | | | | 2,195 | | | | | | 343 | | |