根據2024年10月16日提交給證券交易所審查的文件

註冊號 333-

美國

證券交易委員會

華盛頓特區20549

S-8表格

註冊聲明

根據.

代表股份的存託憑證

CAMP4治療公司

(根據其憲章規定的準確名稱)

CAMP4 Therapeutics 公司修訂和重新制訂 2016年股票期權和授予計劃

CAMP4 Therapeutics Corporation 2024股權激勵計劃

CAMP4 Therapeutics Corporation 2024員工 股票購買計劃

(計劃的完整名稱)

Josh Mandel-Brehm

首席執行官

CAMP4治療公司
康德爾廣場一號，1400西號樓，3樓

麻省劍橋市02139

（服務代理人的姓名和地址）

(617) 651-8867

（服務代理人，包括區號的電話號碼）

請將所有通信-半導體的副本發送至:

Thomas J. Danielski

Ropes & Gray LLP

波士頓保險大廈

800 Boylston 街

馬薩諸塞州波士頓02199-3600

617-951-7000

請在複選框中標註，指明註冊申報者是否爲大型加速申報者、加速申報者、非加速申報者、較小的報告公司或新興成長公司。請參考《交易所法案》第120億.2規定中對「大型加速申報者」、「加速申報者」、「較小的報告公司」和「新興成長公司」的定義。

如果一家新興增長型公司，檢查標記表示註冊人選擇不使用符合證券法7(a)(2)(B)部分的任何新的或修訂的財務會計準則所提供的延期過渡期。 ¨

第一部分

第10(a)區間申報所需的信息

根據1933年修訂版證券法案第428(a)條的規定允許，本登記聲明省略了表格S-8第I部分中指定的信息。包含第I部分指定信息的文件將交付給CAMP4 Therapeutics Corporation修訂後的2016年股票期權和授予計劃、CAMP4 Therapeutics Corporation 2024年股權激勵計劃和CAMP4 Therapeutics Corporation 2024年員工股票購買計劃的參與者，按照第428(b)條的規定進行。此類文件未作爲本登記聲明的一部分或根據證券法424條的規定作爲註冊聲明或招股說明書或招股說明書補充提交給美國證券交易委員會(SEC)。

第II部分

註冊聲明所需的信息

項目3。引用文件

CAMP4 Therapeutics Corporation（以下簡稱「註冊者」）向美國證券交易委員會提交的以下文件已被引入此處：

發行人在此日期之後根據《證券交易法》第13(a)、13(c)、14和15(d)條的規定提交的所有報告和其他文件，在提交本註冊聲明的後期生效修正案並表明此處所提供的所有證券已全部出售或取消註冊所有仍未出售的證券之前，應視爲通過引用並自此之日起成爲本聲明的一部分。此處或通過引用爲此處所確定的任何聲明應被視爲已被修改或取代，以用於此註冊聲明的目的，在此處或在任何隨後提交的報告或文件中，該報告或文件也被引用或視爲已被引用修改或取代了此前的聲明。經修改或取代的任何聲明，除非被修改或取代，否則不應被視爲本註冊聲明的一部分。

項目4.證券描述。

不適用。

項目5.列名專家和法律顧問的利益。

不適用。

項目6:董事和官員的賠償

根據特拉華州《一般公司法》第102(b)(7)條的規定，我們的修訂章程（我們的「修訂章程」）包括一項條款，取消我們的董事和高級職員在履行其董事職責時對金錢損害的個人責任，但存在某些例外情況。此外，我們的修訂章程和修正後的章程規定，我們有義務在特定情況下對我們的高級職員和董事進行賠償，包括那些賠償原本可能是自願的情況，並且我們有義務在針對他們的訴訟案件中預付高級職員和董事的費用，除非《一般公司法》禁止取消或限制董事或高級職員對違反職責的責任。

根據DGCL的第145(a)條款規定，一家公司應有權利賠償任何因爲其作爲公司的董事、高級職員、僱員或代理人，或應公司的要求作爲另一家公司、合夥企業、聯合創業公司、trust或其他企業的董事、高級職員、僱員或代理人，而被威脅或參與任何威脅、進行中或已完成的訴訟、訴訟或調查（除了由公司進行或代表公司進行的訴訟）而導致的支出（包括律師費）、判決、罰款及在結案中實際和合理產生的支付總額，如果該人士是出於善意並且合理相信其行爲符合或不違反公司最佳利益，並且對任何刑事訴訟或訴訟，沒有合理理由認爲該人的行爲不法。任何判決、命令、結案、定罪或認罪和解或其等效的結束，並不能本身產生這樣一種推定，即該人沒有善意並且沒有合理相信其行爲符合或不違反公司最佳利益，並且對於任何刑事訴訟或訴訟，該人有合理理由相信其行爲不法。

Section 145(b) of the DGCL provides that a corporation shall have the power to indemnify any person who was or is a party or is threatened to be made a party to any threatened, pending or completed action or suit by or in the right of the corporation to procure a judgment in its favor by reason of the fact that the person is or was a director, officer, employee or agent of the corporation, or is or was serving at the request of the corporation as a director, officer, employee or agent of another corporation, partnership, joint venture, trust or other enterprise against expenses (including attorneys’ fees) actually and reasonably incurred by the person in connection with the defense or settlement of such action or suit if the person acted in good faith and in a manner the person reasonably believed to be in or not opposed to the best interests of the corporation and except that no indemnification shall be made with respect to any claim, issue or matter as to which such person shall have been adjudged to be liable to the corporation unless and only to the extent that the Court of Chancery or the court in which such action or suit was brought shall determine upon application that, despite the adjudication of liability but in view of all the circumstances of the case, such person is fairly and reasonably entitled to indemnity for such expenses which the Court of Chancery or such other court shall deem proper.

We have entered into indemnification agreements with our directors and executive officers. These indemnification agreements provide broader indemnity rights than those provided under the DGCL and our Restated Charter. These indemnification agreements are not intended to deny or otherwise limit third-party or derivative suits against us or our directors or officers, but to the extent a director or officer were entitled to indemnity or contribution under the indemnification agreement, the financial burden of a third-party suit would be borne by us, and we would not benefit from derivative recoveries against the director or officer. Such recoveries would accrue to our benefit but would be offset by our obligations to the director or officer under the indemnification agreement.

We maintain directors’ and officers’ liability insurance for the benefit of our directors and officers.

Item 7. Exemption from Registration Claimed.

Not applicable.

Item 8. Exhibits.

* Filed herewith.

Item 9. Undertakings.

(a) The undersigned Registrant hereby undertakes:

(1) To file, during any period in which offers or sales are being made, a post-effective amendment to this Registration Statement:

provided, however, that paragraphs (a)(1)(i) and (a)(1)(ii) above shall not apply if the information required to be included in a post-effective amendment by those paragraphs is contained in reports filed with or furnished to the Commission by the Registrant pursuant to Section 13 or 15(d) of the Exchange Act that are incorporated by reference in the Registration Statement.

(b) The undersigned Registrant hereby undertakes that, for purposes of determining any liability under the Securities Act, each filing of the Registrant’s annual report pursuant to Section 13(a) or 15(d) of the Exchange Act (and, where applicable, each filing of an employee benefit plan’s annual report pursuant to Section 15(d) of the Exchange Act) that is incorporated by reference in the Registration Statement shall be deemed to be a new registration statement relating to the securities offered therein, and the offering of such securities at that time shall be deemed to be the initial bona fide offering thereof.

(c) Insofar as indemnification for liabilities arising under the Securities Act may be permitted to directors, officers and controlling persons of the Registrant pursuant to the foregoing provisions, or otherwise, the Registrant has been advised that in the opinion of the SEC such indemnification is against public policy as expressed in the Securities Act and is, therefore, unenforceable. In the event that a claim for indemnification against such liabilities (other than the payment by Registrant of expenses incurred or paid by a director, officer or controlling person of the Registrant in the successful defense of any action, suit or proceeding) is asserted by such director, officer or controlling person in connection with the securities being registered, the Registrant will, unless in the opinion of its counsel the matter has been settled by controlling precedent, submit to a court of appropriate jurisdiction the question whether such indemnification by it is against public policy as expressed in the Securities Act and will be governed by the final adjudication of such issue.

SIGNATURES

Pursuant to the requirements of the Securities Act of 1933, the Registrant certifies that it has reasonable grounds to believe that it meets all of the requirements for filing on Form S-8 and has duly caused this Registration Statement to be signed on its behalf by the undersigned, thereunto duly authorized, in the City of Cambridge, Massachusetts, on this 16th day of October, 2024.

POWER OF ATTORNEY

Each person whose signature appears below constitutes and appoints Josh Mandel-Brehm and Kelly Gold, and each of them singly, his or her true and lawful attorneys-in-fact and agents with full power of substitution and resubstitution, for him or her and in his or her name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective amendments) to this Registration Statement on Form S-8 to be filed by CAMP4 Therapeutics Corporation and to file the same, with all exhibits thereto, and other documents in connection therewith, with the Securities and Exchange Commission, granting unto said attorneys-in-fact and agents full power and authority to be done in and about the premises, as fully to all intents and purposes as he or she might or could do in person, hereby ratifying and confirming all that said attorneys-in-fact and agents, and each of them, or their substitutes, may lawfully do or cause to be done by virtue hereof.

* * * *

Pursuant to the requirements of the Securities Act of 1933, this Registration Statement has been signed by the following persons in the capacities and on the dates indicated: