(NASDAQ:GLYC) today announced that Apollomics has dosed the first patient in China in a Phase 1 clinical trial of APL-106 (uproleselan injection) for the treatment of adults with relapsed or refractory acute myeloid leukemia (AML). In February of this year, Apollomics initiated two Phase 1 study sites in Greater China.

“Dosing of the first patient in Greater China is a significant accomplishment for Apollomics. Equally important is the fact that Apollomics support for uproleselan reflects a broad level of interest in our drug candidate’s potential to make a real difference for AML patients. Clearly, for patients with relapsed/refractory disease, there is a huge unmet need,” noted Rachel King, GlycoMimetics Chief Executive Officer. “We believe that Apollomics’ track record and leadership are particularly qualified to take this program through clinical development and on to commercialization.”

The Phase 1 clinical trial in China is a part of the Phase 1 and Phase 3 bridging clinical study of APL-106 in combination with chemotherapy in adults with relapsed or refractory AML. Its principal investigator is Professor Jianxiang Wang of the Institute of Hematology and Blood Diseases Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College. The primary objective of the Phase 1 trial is to study the pharmacokinetic (PK) characteristics of APL-106 in Chinese subjects with relapsed or refractory AML and to evaluate the safety and tolerability of APL-106 in combination with chemotherapy.