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Reported Earlier, Legend Biotech CARVYKTI Delivers Improved MRD Negativity And Overall Survival Benefits In Phase 3 CARTITUDE-4 Study

Reported Earlier, Legend Biotech CARVYKTI Delivers Improved MRD Negativity And Overall Survival Benefits In Phase 3 CARTITUDE-4 Study

早前报道,传奇生物CARVYKTI在三期CARTITUDE-4研究中显示出改善的微小残留病阴性率和总体生存益处。
Benzinga ·  12/10 15:17
  • 89 percent of evaluable patients achieved minimal residual disease (MRD) negativity with CARVYKTI after three-year follow-up in CARTITUDE-4 study; the majority in less than 2 months
  • Results add to the overall survival (OS) benefit recently reported making CARVYKTI the first and only cell therapy to significantly extend OS versus standard therapies in multiple myeloma
  • Landmark Phase 3 CARTITUDE-4 study data featured as an oral presentation at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition
  • 在CARTITUDE-4研究中,经过三年跟踪,89%的可评估患者在使用CARVYKTI后达到了微小残留病(MRD)阴性;大多数患者在不到2个月内达成这一结果。
  • 结果补充了最近报告的总体生存(OS)益处,证明CARVYKTI是首个也是唯一一个在多发性骨髓瘤中相比标准疗法显著延长OS的电芯疗法。
  • 作为口头报告,CARTITUDE-4的里程碑III期研究数据在第66届美国血液学会(ASH)年会和博览会上进行了展示。

译文内容由第三方软件翻译。


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