TD Cowen analyst Yaron Werber maintains $Alector (ALEC.US)$ with a buy rating.
According to TipRanks data, the analyst has a success rate of 55.2% and a total average return of 12.1% over the past year.
Furthermore, according to the comprehensive report, the opinions of $Alector (ALEC.US)$'s main analysts recently are as follows:
Following the Phase 2 INVOKE-2 study, where AL002 did not show effectiveness in slowing Alzheimer's progression or impacting disease biomarkers, analysts have moderated their outlook. Potential remains noted for latozinemab, though the focus may shift towards other opportunities within their coverage, pending late-stage data in frontotemporal dementia expected around late 2025 to early 2026.
The TREM2 activation showed minimal impact in treating Alzheimer's disease, which poses challenges for the approach of using genome-wide association studies-driven medicine. Additionally, there may be a need to reassess the mechanism of ARIA-E.
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TD Cowen分析师Yaron Werber维持$Alector (ALEC.US)$买入评级。
根据TipRanks数据显示，该分析师近一年总胜率为55.2%，总平均回报率为12.1%。
此外，综合报道，$Alector (ALEC.US)$近期主要分析师观点如下：
在 INVOKE-2 第 2 期研究中，AL002 并未显示出减缓阿尔茨海默氏症进展或影响疾病生物标志物的有效性，此后，分析师们调整了他们的展望。拉托津单抗的潜力仍然显而易见，尽管焦点可能会转移到其覆盖范围内的其他机会上，但尚待预计在2025年底至2026年初左右获得额颌痴呆的后期数据。
TREM2 的激活对治疗阿尔茨海默氏病的影响微乎其微，这给使用全基因组关联研究驱动的药物的方法带来了挑战。此外，可能需要重新评估ARIA-E的机制。
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