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Tetra Pharm Technologies and Kvantify Announce Partnership to Accelerate the Discovery of Novel Drug Candidates Targeting the Endocannabinoid System

Tetra Pharm Technologies and Kvantify Announce Partnership to Accelerate the Discovery of Novel Drug Candidates Targeting the Endocannabinoid System

Tetra Pharm Technologies和Kvantify宣佈建立合作伙伴關係,以加快針對內源性大麻素系統的新型候選藥物的發現
PR Newswire ·  05/30 16:00

The collaboration between two Danish companies aims to revolutionize drug discovery with help from quantum computing, AI and computer-aided drug design.

兩家丹麥公司之間的合作旨在藉助量子計算、人工智能和計算機輔助藥物設計徹底改變藥物發現。

COPENHAGEN, Denmark, May 30, 2024 /PRNewswire/ -- Tetra Pharm Technologies and Kvantify join forces in a strategic partnership to accelerate the identification and development of novel drug candidates targeting the endocannabinoid system (ECS).

丹麥哥本哈根,2024年5月30日 /PRNewswire/ — Tetra Pharm Technologies和Kvantify聯手建立戰略伙伴關係,以加快針對內源性大麻素系統(ECS)的新型候選藥物的鑑定和開發。

M.Rose & HH.Knudsen
M.Rose 和 HH.Knudsen

"We are proud to partner with Kvantify, a company that shares our passion for scientifically based technological solutions to real-world challenges. This partnership will expedite our drug development process and significantly expand our pipeline of promising drug candidates in 2024," says Martin Rose, Chief Executive Officer of Tetra Pharm Technologies.

“我們很榮幸能與Kvantify合作,該公司和我們一樣熱衷於以科學爲基礎的技術解決方案,以應對現實挑戰。這種夥伴關係將加快我們的藥物研發進程,並在2024年顯著擴大我們有前途的候選藥物的產品線。” 利樂科技首席執行官馬丁·羅斯說。

This partnership is poised to transform the landscape of ECS-targeted drug discovery, potentially leading to significant advancements in therapeutic options for patients.

這種夥伴關係有望改變ECS靶向藥物發現的格局,有可能爲患者帶來治療選擇的重大進展。

Exploring key receptors

探索關鍵受體

Together, the partners will go deep into the complexities of endocannabinoid receptors and their interactions with potential drug candidates from Tetra Pharm Technologies' pipeline. This approach is expected to not only advance the existing pipeline significantly but also lead to new discoveries within the field.

合作伙伴將共同深入探討內源性大麻素受體的複雜性及其與利樂科技產品線中潛在候選藥物的相互作用。預計這種方法不僅將顯著推進現有管道,而且還將導致該領域的新發現。

At this point, Tetra Pharm Technologies has 11 drug candidates in its pipeline, each targeting specific receptors with distinct modes of action and more candidates on their way. For each pipeline candidate Tetra Pharm Technologies pursues a distinct mode of action at the receptor level based on their scientists' understanding of the endocannabinoid system; that is, which receptors they wish to hit, and – equally important – which receptors to be avoided in terms of side effect profile.

目前,Tetra Pharm Technologies有11種候選藥物正在研發中,每種候選藥物都針對具有不同作用模式的特定受體,還有更多的候選藥物正在研發中。對於每種候選藥物,Tetra Pharm Technologies根據其科學家對內源性大麻素系統的理解,在受體層面追求不同的作用模式;即他們希望擊中哪些受體,以及——同樣重要的是——在副作用特徵方面應避免使用哪些受體。

"The Kvantify platform enables us to screen much broader and to more effectively identify key structural attributes of our drug candidates to guide our in-vitro cellular pharmacology and ultimately our CMC activities. Since the potential formulation hassles have already been mitigated with our proprietary drug delivery system, we can undoubtedly progress candidates even faster through our pipeline," says Dr. Morten Allesø, Chief Scientific Officer at Tetra Pharm Technologies.

“Kvantify平台使我們能夠更廣泛的篩選,更有效地識別候選藥物的關鍵結構特徵,以指導我們的體外細胞藥理學,最終指導我們的CMC活動。由於我們專有的藥物遞送系統已經緩解了潛在的配方麻煩,因此我們無疑可以更快地在研發線中開發候選藥物。” 利樂科技首席科學官莫滕·艾勒索博士說。

Comprehensive screening and advanced insights

全面篩選和高級見解

The collaboration involves a comprehensive screening of nearly 1,000 molecular combinations suspected of acting as ligands to endocannabinoid receptors. This screening is conducted using Kvantify's CNS module, providing Tetra Pharm Technologies additional insight into the propensity for blood-brain-barrier penetration.

該合作涉及對近1,000種涉嫌充當內源性大麻素受體配體的分子組合進行全面篩選。該篩查是使用Kvantify的中樞神經系統模塊進行的,這使利樂製藥能夠進一步了解血腦屏障穿透的傾向。

Nils Anton Berglund, Head of Strategic Alliances at Kvantify, highlights the potential impact.

Kvantify戰略聯盟負責人尼爾斯·安東·伯格倫德強調了潛在的影響。

"The endocannabinoid system has been under-leveraged in drug discovery and it represents a huge opportunity for innovation. With Tetra Pharm Technologies' deep knowledge of the endocannabinoid biology and the atomistic level precision that Kvantify's CNS drug discovery platform can deliver, we believe the collaboration can uncover ground-breaking new science for the benefit of patients around the globe."

“內源性大麻素系統在藥物發現中的槓桿作用不足,它爲創新提供了巨大的機會。憑藉利樂製藥科技對內源性大麻素生物學的深入了解以及Kvantify的中樞神經系統藥物發現平台可以提供的原子級精度,我們相信此次合作可以發現突破性的新科學,造福全球患者。”

"This is an extremely exciting collaboration leveraging cutting-edge research from both parties," says Hans Henrik Knudsen, Chief Executive Officer at Kvantify and continues.

Kvantify首席執行官漢斯·亨裏克·克努森說:“利用雙方的尖端研究,這是一次非常令人興奮的合作。”

"The combination of Tetra Pharm Technologies' novel drug delivery technology with Kvantify's computational drug discovery platform, makes for an incredibly exciting synergy that will facilitate more rapid and efficient development of novel drugs."

“Tetra Pharm Technologies的新型藥物遞送技術與Kvantify的計算藥物發現平台相結合,產生了令人難以置信的令人興奮的協同作用,將促進更快更高效地開發新藥。”

About Tetra Pharm Technologies ApS

關於利樂製藥科技APs

Tetra Pharm Technologies is a Danish biopharmaceutical company established in 2018 with a vision to be a leader in research and development of pharmaceutical drugs for the treatment of diseases related to the endocannabinoid system. For more information, please visit ().

Tetra Pharm Technologies是一家丹麥生物製藥公司,成立於2018年,其願景是成爲治療內源性大麻素系統相關疾病的藥物研發領域的領導者。欲了解更多信息,請訪問 ()。

About Kvantify

關於 Kvantify

Kvantify is a leading quantum company from Denmark that delivers software solutions and services to tackle the world's most challenging and valuable problems in areas such as biotechnology and medicine. Established in 2022, the company today comprises more than 65 experts in a broad range of fields, from quantum computing and software engineering to mathematics, physics, cheminformatics, and computational chemistry. For more information, please visit ().

Kvantify是一家來自丹麥的領先量子公司,提供軟件解決方案和服務,以解決生物技術和醫學等領域世界上最具挑戰性和最有價值的問題。該公司成立於2022年,如今由來自量子計算和軟件工程到數學、物理、化學信息學和計算化學等廣泛領域的65多名專家組成。欲了解更多信息,請訪問 ()。

For further information

欲了解更多信息

Jacob Schlundt
Chief Marketing Officer
Tetra Pharm Technologies
[email protected]
+45 5197 6225

雅各布·施倫特
首席營銷官
利樂製藥科技
[電子郵件保護]
+45 5197 6225

Morten Dalgaard-Thestrup
Head of Marketing & Communication
Kvantify
[email protected]
+45 61759082

Morten Dalgaard-Thestrup
營銷與傳播主管
Kvantify
[電子郵件保護]
+45 61759082

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SOURCE Tetra Pharm Technologies

來源 Tetra Pharm 科技

譯文內容由第三人軟體翻譯。


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