U.S. stocks are poised to open lower on Wednesday following the boost from the tech rally in the previous session. The spotlight will likely be on bond yields, which have climbed in recent sessions on hopes of a "higher-for-longer" monetary policy stance. Traders may also draw clues from some key retail earnings reports due ahead of the market open, Federal Reserve officials' speeches, the central bank's Beige Book report, and the reception to a Treasury auction. Renewed geopolitical tensions in the Middle East may dampen risk appetite.

In premarket trading on Wednesday, the SPDR S&...