Teknova Launches Proprietary Build-Tek Solutions Custom Configurator and Latest AAV-Tek Product to Further Accelerate Novel Therapy Development
Teknova Launches Proprietary Build-Tek Solutions Custom Configurator and Latest AAV-Tek Product to Further Accelerate Novel Therapy Development
First-of-its-kind custom configurator – available today – gives scientists access to high quality, customizable buffers in small volumes for use in early-stage experiments, all with exceptionally short turnaround times
首款定製配置器（現已上市）使科學家能夠獲得高質量、可定製的小容量緩衝液，用於早期實驗，而且週轉時間極短
Novel, multi-purpose AAV stabilizer solution increases capsid yield up to 50% while safeguarding product integrity across the AAV purification workflow
新穎的多用途 AAV 穩定劑解決方案可將衣殼產量提高多達 50%，同時在整個 AAV 純化工作流程中保護產品完整性
HOLLISTER, Calif., May 07, 2024 (GLOBE NEWSWIRE) -- Alpha Teknova, Inc. ("Teknova") (Nasdaq: TKNO), a leading producer of critical reagents for the discovery, development, and commercialization of novel therapies, vaccines, and molecular diagnostics, today launched the Company's first custom product configurator, Build-TekTM Solutions, specifically created to address the need for fast turnaround, high-quality buffers for use during early-stage therapy development. Teknova also announced the availability of the latest product in their proprietary AAV-TekTM Solutions product line – the AAV-Tek AAV Stabilizer – that substantially improves recovery and protects capsid integrity across the purification workflow.
加利福尼亞州霍利斯特，2024年5月7日（GLOBE NEWSWIRE）——用於新療法、疫苗和分子診斷髮現、開發和商業化的關鍵試劑的領先生產商Alpha Teknova, Inc.（“TKNO”）（納斯達克股票代碼：TKNO）今天推出了公司的首款定製產品配置器——Build-TekTM Solutions，專爲滿足快速週轉和高質量需求而設計用於早期療法開發的緩衝液。Teknova還宣佈其專有AAV-TekTM Solutions產品系列中的最新產品——AAV-Tek AAV穩定劑——上市，該產品可顯著提高回收率並保護整個純化工作流程中的衣殼完整性。
"I'm incredibly proud of our talented team and their unwavering focus on making solutions possible for our customers by addressing critical pain points during therapeutic development," said Stephen Gunstream, President and Chief Executive Officer. "With the launch of Build-Tek Solutions, we're now able to support research scientists with small volumes of multiple discrete buffer formulations that are made from high-quality raw materials and QC tested. Our custom configurator is easy to use, and by leveraging our modular manufacturing platform, products ship in a matter of days. Now scientists can focus on advancing science by getting reproducible, trusted results during their early-stage experiments instead of spending their time mixing buffers."
總裁兼首席執行官Stephen Gunstream表示：“我爲我們才華橫溢的團隊以及他們堅定不移地致力於通過解決治療開發過程中的關鍵痛點爲我們的客戶提供解決方案感到非常自豪。”“隨着Build-Tek Solutions的推出，我們現在能夠爲研究科學家提供少量多種離散緩衝配方，這些配方由高質量原材料製成，並經過質量控制測試。我們的定製配置器易於使用，通過利用我們的模塊化製造平台，產品可在幾天之內發貨。現在，科學家們可以在早期實驗中獲得可重複、可信的結果，從而專注於推動科學發展，而不必花時間混合緩衝液。”
Build-Tek Solutions is a fast turnaround, custom manufacturing platform that enables the customization of multiple, iterative buffers needed during early-stage research and design of experiments (DOE). By using an online custom configurator, scientists can order discrete buffer formulations combining a base buffer with optional salts and other additives in one-liter bottles, with no minimum order quantities. All buffers are made in an ISO 13485 certified facility using high-quality ingredients, and all raw materials and finished products are rigorously tested using USP-based quality control assays to ensure consistent quality and performance. Build-Tek makes buffers more efficiently and to higher quality standards than buffers made in the lab, enabling research scientists to eliminate a critical variable in their experiments and reduce the risk of inaccurate results and experimental failures.
Build-Tek Solutions是一個快速週轉的定製製造平台，可以定製早期研究和實驗設計（DOE）所需的多個迭代緩衝區。通過使用在線定製配置器，科學家可以訂購分立的緩衝液配方，將基礎緩衝液與可選鹽和其他添加劑裝在一升的瓶子中，沒有最低訂購量。所有緩衝液均在經過ISO 13485認證的設施中使用高質量原料製成，所有原材料和成品均使用基於USP的質量控制分析進行嚴格測試，以確保穩定的質量和性能。與實驗室製造的緩衝液相比，Build-Tek使緩衝液更高效，符合更高的質量標準，這使研究科學家能夠消除實驗中的關鍵變量，降低結果不準確和實驗失敗的風險。
Build-Tek Solutions is available online today for orders of multiple iterations of Tris and phosphate buffers, along with a variety of optional salts and additives, with more base solutions and additives coming soon. Each one-liter bottle of base solution starts at $119; additional salts or additives are $15 each. Orders of up to 20 buffer formulations will ship within two days. Customers placing larger orders should contact Teknova directly for estimated shipping dates.
Build-Tek Solutions今天可以在線訂購多次迭代的Tris和磷酸鹽緩衝液以及各種可選鹽和添加劑，更多基礎溶液和添加劑即將上市。每瓶一升基礎溶液起價爲119美元；其他鹽或添加劑每瓶15美元。最多 20 種緩衝配方的訂單將在兩天內發貨。下較大訂單的買家應直接聯繫 Teknova 了解預計的發貨日期。
"We're also expanding our support for gene therapy developers with the latest offering in our AAV-Tek Solutions proprietary product line, the AAV-Tek AAV Stabilizer," continued Mr. Gunstream. "This entire suite of product solutions is designed to target known pain points across the AAV workflow, and our new multi-purpose stabilizer is a powerhouse that significantly improves capsid yield – up to 50% – while protecting their functional integrity."
Gunstream先生繼續說：“我們還通過我們的AAV-Tek Solutions專有產品系列中的最新產品——AAV-Tek AAV穩定器，擴大對基因療法開發人員的支持。”“整套產品解決方案旨在針對 AAV 工作流程中的已知痛點，而我們新的多用途穩定劑是一款強勁的產品，可在保護其功能完整性的同時，顯著提高衣殼產量（高達 50%）。”
Only from Teknova, the AAV-Tek AAV Stabilizer is for use during the filtration and capture steps of downstream processing and is designed to help achieve substantial recovery improvements while safeguarding the AAV product. Using a proprietary blend of poloxamer and sucrose, this multi-purpose, concentrated solution reduces turbidity and pressure during filtration, preventing aggregation, significantly increasing the recovery of functional capsids by up to 50%.
只有來自Teknova的AAV-Tek AAV穩定器適用於下游處理的過濾和捕獲步驟，旨在幫助實現實質性的恢復改善，同時保護AAV產品。這種多用途的濃縮溶液使用泊洛沙姆和蔗糖的專有混合物，可降低過濾過程中的濁度和壓力，防止聚集，從而顯著提高多達50％的功能性衣殼的回收率。
The AAV-Tek AAV Stabilizer is a 100x concentrated solution that can be directly spiked into feed stock, buffers, and solutions, providing an easy-to-use and powerful safety factor for gene therapy developers to confidently progress across the AAV purification workflow, saving time and resources. It is ready to ship in 100 mL and 500 mL formats, and can be purchased via phone, email, or online. The 100 mL size is priced at $95 and the 500 mL size is priced at $245 per bottle.
AAV-Tek AAV Stabilizer 是一種 100 倍濃縮的解決方案，可以直接加入原料、緩衝液和溶液中，爲基因療法開發人員提供了易於使用且強大的安全係數，使他們能夠自信地在 AAV 純化工作流程中取得進展，從而節省時間和資源。它已準備好以 100 mL 和 500 mL 格式發貨，可以通過電話、電子郵件或在線購買。100 毫升容量的售價爲 95 美元，500 毫升容量的售價爲每瓶 245 美元。
譯文內容由第三人軟體翻譯。