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Teknova Launches Proprietary Build-Tek Solutions Custom Configurator and Latest AAV-Tek Product to Further Accelerate Novel Therapy Development

Teknova Launches Proprietary Build-Tek Solutions Custom Configurator and Latest AAV-Tek Product to Further Accelerate Novel Therapy Development

Teknova推出专有的Build-Tek解决方案定制配置器和最新的AAV-Tek产品,进一步加快新型治疗方法的开发。
GlobeNewswire ·  05/07 22:00

First-of-its-kind custom configurator – available today – gives scientists access to high quality, customizable buffers in small volumes for use in early-stage experiments, all with exceptionally short turnaround times

首个定制配置器——今天上市——为科学家提供高质量、可定制的小容量缓冲液,用于早期实验,而且转化时间非常短。

Novel, multi-purpose AAV stabilizer solution increases capsid yield up to 50% while safeguarding product integrity across the AAV purification workflow

新颖的多功能AAV稳定剂溶液,可使衣壳产量增加50%,同时保护整个AAV纯化工序的产品完整性。

HOLLISTER, Calif., May  07, 2024  (GLOBE NEWSWIRE) -- Alpha Teknova, Inc. ("Teknova") (Nasdaq: TKNO), a leading producer of critical reagents for the discovery, development, and commercialization of novel therapies, vaccines, and molecular diagnostics, today launched the Company's first custom product configurator, Build-TekTM Solutions, specifically created to address the need for fast turnaround, high-quality buffers for use during early-stage therapy development. Teknova also announced the availability of the latest product in their proprietary AAV-TekTM Solutions product line – the AAV-Tek AAV Stabilizer – that substantially improves recovery and protects capsid integrity across the purification workflow.

2024年5月7日,加州荷利斯特(Hollister)(环球新闻社) - Alpha Teknova,Inc.("Teknova")(纳斯达克证券交易所:TKNO),一家领先的关键试剂生产商,致力于发现、开发和商业化新型治疗法、疫苗和分子诊断方案,今天推出了公司的首个定制产品配置器 Build-TekTM Solutions,专为快速反应、高质量缓冲液的需求而创建,供用于早期治疗开发过程中。Teknova还宣布推出他们专有的AAV-TekTM Solutions产品线中最新产品AAV-Tek AAV稳定剂,该产品在纯化工序中显著提高恢复率,并保护衣壳完整性。

"I'm incredibly proud of our talented team and their unwavering focus on making solutions possible for our customers by addressing critical pain points during therapeutic development," said Stephen Gunstream, President and Chief Executive Officer. "With the launch of Build-Tek Solutions, we're now able to support research scientists with small volumes of multiple discrete buffer formulations that are made from high-quality raw materials and QC tested. Our custom configurator is easy to use, and by leveraging our modular manufacturing platform, products ship in a matter of days. Now scientists can focus on advancing science by getting reproducible, trusted results during their early-stage experiments instead of spending their time mixing buffers."

"我非常为我们充满才华的团队和他们毫不动摇地专注于通过解决疗法开发中的关键痛点为我们的客户提供解决方案而感到自豪,"首席执行官Stephen Gunstream表示。" 通过推出Build-Tek Solutions,我们现在能够支持研究科学家使用小容量的多个离散缓冲液配方,这些缓冲液由高质量原材料制成,并经过质量控制测试。我们的定制配置器易于使用,并通过利用我们的模块化制造平台,产品在几天内即可发货。现在,科学家可以专注于推动科学的发展,在早期实验中获得可重复、值得信赖的结果,而不是将时间花在混合缓冲液上。"

Build-Tek Solutions is a fast turnaround, custom manufacturing platform that enables the customization of multiple, iterative buffers needed during early-stage research and design of experiments (DOE). By using an online custom configurator, scientists can order discrete buffer formulations combining a base buffer with optional salts and other additives in one-liter bottles, with no minimum order quantities. All buffers are made in an ISO 13485 certified facility using high-quality ingredients, and all raw materials and finished products are rigorously tested using USP-based quality control assays to ensure consistent quality and performance. Build-Tek makes buffers more efficiently and to higher quality standards than buffers made in the lab, enabling research scientists to eliminate a critical variable in their experiments and reduce the risk of inaccurate results and experimental failures.

Build-Tek Solutions是一种快速反应的定制制造平台,能够在早期研究和设计实验(DOE)期间对多个迭代的缓冲液进行定制。科学家可以通过在线定制配置器来订购包含基础缓冲液和可选盐和其他添加剂的离散缓冲液配方,容量均为1升瓶,无最低订单量限制。所有缓冲液均在 ISO 13485 认证的设施中使用高质量原料制成,并使用基于 USP 的质量控制试验对所有原材料和成品进行严格测试,以确保一致的质量和性能。Build-Tek 比实验室中制备的缓冲液更高效、更高质量,使研究科学家能够消除实验中的一个关键变量,降低不准确结果和实验失败的风险。

Build-Tek Solutions is available online today for orders of multiple iterations of Tris and phosphate buffers, along with a variety of optional salts and additives, with more base solutions and additives coming soon. Each one-liter bottle of base solution starts at $119; additional salts or additives are $15 each. Orders of up to 20 buffer formulations will ship within two days. Customers placing larger orders should contact Teknova directly for estimated shipping dates.

Build-Tek Solutions今天可在线订购Tris和磷酸盐缓冲液的多个迭代版本,以及各种可选盐和添加剂,更多基础溶液和添加剂即将推出。每个基础溶液的1升瓶起价为119美元;其他盐或添加剂的价格为15美元。最多20种缓冲液配方的订单将在2天内发货。订购更大量订单的客户应直接联系Teknova以获取预计发货日期。

"We're also expanding our support for gene therapy developers with the latest offering in our AAV-Tek Solutions proprietary product line, the AAV-Tek AAV Stabilizer," continued Mr. Gunstream. "This entire suite of product solutions is designed to target known pain points across the AAV workflow, and our new multi-purpose stabilizer is a powerhouse that significantly improves capsid yield – up to 50% – while protecting their functional integrity."

"我们也在扩大我们对基因治疗开发者的支持,推出了AAV-Tek Solutions专有产品线中的最新产品AAV-Tek AAV稳定剂,"Gunstream先生继续说道。" 这整套产品解决方案的设计目标是针对AAV工作流程中已知的痛点,而我们的新型多功能稳定剂则是一个强大的内核,可显著提高衣壳产量,达到50%以上,并保护它们的功能完整性。"

Only from Teknova, the AAV-Tek AAV Stabilizer is for use during the filtration and capture steps of downstream processing and is designed to help achieve substantial recovery improvements while safeguarding the AAV product. Using a proprietary blend of poloxamer and sucrose, this multi-purpose, concentrated solution reduces turbidity and pressure during filtration, preventing aggregation, significantly increasing the recovery of functional capsids by up to 50%.

AAV-Tek AAV稳定剂是为下游处理的过滤和捕获步骤使用,旨在帮助实现实质性的恢复率改善,同时保护AAV产品。该多用途浓缩溶液使用Poloxamer和蔗糖的专有混合物,可在过滤过程中减少浑浊度和压力,避免聚集,并将功能衣壳的回收率显着提高50%。

The AAV-Tek AAV Stabilizer is a 100x concentrated solution that can be directly spiked into feed stock, buffers, and solutions, providing an easy-to-use and powerful safety factor for gene therapy developers to confidently progress across the AAV purification workflow, saving time and resources. It is ready to ship in 100 mL and 500 mL formats, and can be purchased via phone, email, or online. The 100 mL size is priced at $95 and the 500 mL size is priced at $245 per bottle.

AAV-Tek AAV稳定剂是一种100倍浓缩溶液,可直接加到进料、缓冲液和溶液中,为基因治疗开发人员提供易于使用的强大安全因素,自信地跨越AAV纯化工作流程,节省时间和资源。它以100毫升和500毫升瓶装发售,可通过电话、电子邮件或在线购买。100毫升规格的售价为95美元,500毫升规格的售价为245美元/瓶。

译文内容由第三方软件翻译。


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