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Theralase(R) Granted Canadian Cancer Vaccine Patent

Theralase(R) Granted Canadian Cancer Vaccine Patent

Theralase (R) 獲得加拿大癌症疫苗專利
Accesswire ·  04/05 19:00

TORONTO, ON / ACCESSWIRE / April 5, 2024 / Theralase Technologies Inc. ("Theralase" or the "Company") (TSXV:TLT)(OTCQB:TLTFF), a clinical stage pharmaceutical company dedicated to the research and development of light and/or radiation activated Photo Dynamic Compounds ("PDCs") for the safe and effective destruction of various cancers, bacteria and viruses, has been granted a Canadian patent for a new cancer vaccine.

安大略省多倫多/ACCESSWIRE /2024年4月5日/Theralase Technologies Inc.(“Theralase” 或 “公司”)(多倫多證券交易所股票代碼:TLT)(OTCQB: TLTFF)是一家臨床階段製藥公司,致力於研究和開發用於安全有效銷燬各種癌症、細菌和病毒的光和/或輻射活化光動力化合物(“PDC”),已獲得加拿大專利一種新的癌症疫苗。

The recently issued patent is titled, "Vaccine Containing Cancer Cells Inactivated by Photodynamic Treatment with Metal-Based Coordination Complexes and Immunotherapy Method Using Same".

最近發佈的專利的標題是,”含有癌細胞的疫苗通過金屬基配位複合物的光動力學處理和使用該複合物的免疫治療方法“。

A US patent protecting the same technology was previously issued in October 2022. A European Union patent is currently pending.

保護相同技術的美國專利此前已於2022年10月發佈。一項歐盟專利目前正在申請中。

The patent protects Theralase PDC technology in the treatment of a patient with a cancer vaccine; specifically, programmed to destroy their cancer.

該專利保護了使用癌症疫苗治療患者的Theralase PDC技術;具體而言,該技術旨在消滅他們的癌症。

This is fundamentally accomplished by obtaining a sample of their cancer and treating it extracorporeally with a Theralase PDC and then activating the PDC with either light or radiation. This inactivated cancer is then injected back into the patient intravenously, programming the patient's immune system to recognize, attack and destroy the particular cancer of interest.

這基本上是通過獲取他們的癌症樣本並使用Theralase PDC進行體外治療,然後用光或輻射激活PDC來實現的。然後,通過靜脈注射將這種滅活的癌症注射回患者體內,對患者的免疫系統進行編程,以識別、攻擊和摧毀感興趣的特定癌症。

Theralase's pipeline includes: a Phase II registration clinical study for bladder cancer expected to be completed in 2026, plans to launch a Phase Ib clinical study for both brain cancer and lung cancer in 2024, pending completion of a toxicology analysis, and now after the issuance of a Canadian and US patent on a cancer vaccine, the ability to treat various "liquid cancers"; such as leukemia, lymphoma and myeloma.

Theralase的產品線包括:一項預計於2026年完成的膀胱癌二期註冊臨床研究,計劃在2024年啓動一項針對腦癌和肺癌的Ib期臨床研究,等待毒理學分析的完成,以及在加拿大和美國的癌症疫苗專利發佈之後,還包括治療各種 “液體癌” 的能力;例如白血病、淋巴瘤和骨髓瘤。

Dr. Arkady Mandel, MD, PhD, DSc, Chief Scientific Officer of Theralase, inventor of the patent stated, "The issuance of an additional patent for our cancer vaccine technology represents a significant opportunity for patients diagnosed with blood-related cancers, which are difficult, if not impossible, to treat. Our primary focus has been on the research and development of technology to destroy solid-core tumours, such as bladder, brain and lung cancers; however, this new patent allows the Company the opportunity to explore the treatment of various liquid cancers."

該專利的發明者Theralase首席科學官醫學博士、博士、博士學位Arkady Mandel博士表示:“我們的癌症疫苗技術額外專利的簽發對於被診斷患有血液相關癌症的患者來說是一個重要機會,這些癌症很難甚至不可能治療。我們的主要重點是研究和開發消滅膀胱癌、腦癌和肺癌等固體核心腫瘤的技術;但是,這項新專利使公司有機會探索各種液體癌的治療方法。”

Roger DuMoulin-White, President and Chief Executive Officer of Theralase stated, "The possibilities and opportunities of our PDC technology continue to grow at a rapid pace. The Company plans to become properly financed this year through various equity and debt instruments to allow the Company the opportunity to commence new clinical studies focused on the destruction of both solid-core and liquid cancers. I am excited about the opportunities available to the Company, as a result of these new patents, as it significantly increases the opportunity for our PDC technology to treat patients inflicted with a wide range of cancers."

Theralase總裁兼首席執行官羅傑·杜穆林-懷特表示:“我們的PDC技術的可能性和機遇繼續快速增長。該公司計劃今年通過各種股權和債務工具獲得適當的融資,使公司有機會開始新的臨床研究,重點是摧毀固體癌和液體癌。我對公司因這些新專利而獲得的機會感到興奮,因爲這極大地增加了我們的PDC技術治療患有各種癌症的患者的機會。”

About Leukemia:

關於白血病:

Leukemia is a cancer that starts in the stem cells of blood. As the stem cells of the blood develop, they become blast cells (blasts), which are immature blood cells. In leukemia, there is an overproduction of blast cells. These blast cells develop abnormally and don't develop into mature blood cells. Over time, the blast cells crowd out normal blood cells so that they can't do their jobs.

白血病是一種起源於血液幹細胞的癌症。隨着血液中幹細胞的發育,它們會變成爆炸細胞(blasts),即未成熟的血細胞。在白血病中,母細胞會過度產生。這些爆炸細胞發育異常,不會發育成成熟的血細胞。隨着時間的推移,爆炸細胞會擠出正常的血細胞,因此它們無法發揮作用。

Leukemia is the 11th most common cancer in the United States. As of 2019, more than 470,000 Americans have a history of leukemia. It was estimated that about 60,000 people would be diagnosed with leukemia in 2022. The five-year relative survival rate of leukemia is 65.7%.

白血病是 11第四 美國最常見的癌症。截至2019年,超過47萬美國人有白血病史。據估計,到2022年,約有6萬人將被診斷出患有白血病。白血病的五年相對存活率爲65.7%。

About Lymphoma:

關於淋巴瘤:

Lymphoma is a type of cancer that occurs due to the malignant transformation of the lymphocytes (infection fighting cells of the immune system). The most common category of lymphoma, Non-Hodgkin Lymphoma ("NHL") is the 7th most common cancer in the United States. In 2024, the American Cancer Society's estimates 80,620 people (44,590 males and 36,030 females) will be diagnosed with NHL. The five-year relative survival rate of lymphoma is 72%.

淋巴瘤是一種由於淋巴細胞(免疫系統的抗感染細胞)的惡性轉化而發生的癌症。淋巴瘤最常見的類別,非霍奇金淋巴瘤(“NHL”)是 7第四 美國最常見的癌症。據美國癌症協會估計,到2024年,將有80,620人(44,590名男性和36,030名女性)被診斷出患有NHL。淋巴瘤的五年相對存活率爲72%。

About Myeloma:

關於骨髓瘤:

Myeloma, also known as multiple myeloma, is a type of blood cancer that develops from plasma cells in the bone marrow. Myeloma is the 14th most common type of cancer. In 2023, an estimated 35,730 adults in the United States will be diagnosed with multiple myeloma. The overall 5-year survival rate for people with multiple myeloma in the United States is 55%.

骨髓瘤,也稱爲多發性骨髓瘤,是一種由骨髓中的漿細胞發育而成的血液癌。骨髓瘤是 14第四 最常見的癌症類型。2023年,美國估計有35,730名成年人將被診斷出患有多發性骨髓瘤。在美國,多發性骨髓瘤患者的總5年存活率爲55%。

About RuvidarTM:

關於 RuvidarTM:

RuvidarTM is a peer-reviewed, patented PDC currently under investigation in a Phase II registration clinical study for bladder cancer.

魯維達爾TM 是一項經過同行評審的專利PDC,目前正在膀胱癌的II期註冊臨床研究中進行研究。

About Theralase Technologies Inc.:

關於 Theralase 科技公司:

Theralase is a clinical stage pharmaceutical company dedicated to the research and development of light activated compounds, their associated drug formulations and the light systems that activate them, with a primary objective of efficacy and a secondary objective of safety in the destruction of various cancers, bacteria and viruses.

Theralase是一家臨床階段的製藥公司,致力於研究和開發光活化合物、其相關藥物配方和激活它們的光系統,其主要目標是療效,次要目標是銷燬各種癌症、細菌和病毒的安全性。

Additional information is available at and

更多信息可在和

Neither TSX Venture Exchange nor its Regulation Services Provider (as that term is defined in the policies of the TSX Venture Exchange) accepts responsibility for the adequacy or accuracy of this release.

多倫多證券交易所風險投資交易所及其監管服務提供商(該術語在多倫多證券交易所風險交易所的政策中定義)均不對本新聞稿的充分性或準確性承擔責任。

Forward Looking Statements:

前瞻性陳述:

This news release contains "forward-looking statements" within the meaning of applicable Canadian securities laws. Such statements include; but are not limited to statements regarding the Company's proposed development plans with respect to Photo Dynamic Compounds and their drug formulations. Forward looking statements may be identified by the use of the words "may, "should", "will", "anticipates", "believes", "plans", "expects", "estimate", "potential for" and similar expressions; including, statements related to the current expectations of Company's management for future research, development and commercialization of the Company's Photo Dynamic Compounds and their drug formulations, preclinical research, clinical studies and regulatory approvals.

本新聞稿包含適用的加拿大證券法所指的 “前瞻性陳述”。此類聲明包括但不限於有關公司光動力化合物及其藥物配方的擬議開發計劃的聲明。前瞻性陳述可以通過使用 “可能、“應該”、“將”、“預期”、“相信”、“計劃”、“期望”、“估計”、“潛力” 等詞語來識別;包括與公司管理層當前對公司光動態化合物及其藥物配方、臨床前研究、臨床研究和監管批准的未來研究、開發和商業化預期相關的陳述。

These statements involve significant risks, uncertainties and assumptions; including, the ability of the Company to: adequately fund and secure the requisite regulatory approvals to commercially market a treatment for various cancers in a timely fashion and implement its commercialization strategy. Other risks include: the ability of the Company to successfully complete its clinical study program, access to sufficient capital to fund the Company's operations may not be available or may not be available on terms that are commercially favorable to the Company, the Company's drug formulations may not be effective against the diseases tested in its clinical studies, the Company's fails to comply with the term of license agreements with third parties and as a result loses the right to use key intellectual property in its business, the Company's ability to protect its intellectual property, the timing and success of submission, acceptance and approval of regulatory filings. Many of these factors that will determine actual results are beyond the Company's ability to control or predict.

這些陳述涉及重大風險、不確定性和假設;包括公司有能力:提供充足的資金和獲得必要的監管批准,以便及時將各種癌症的治療藥物商業化銷售並實施其商業化戰略。其他風險包括:公司有能力成功完成其臨床研究計劃,可能無法獲得足夠的資金來資助公司的運營,或者可能無法以對公司有利的條件提供,公司的藥物配方可能對臨床研究中測試的疾病無效,公司未能遵守與第三方簽訂的許可協議條款,因此失去在其業務中使用關鍵知識產權的權利,公司的保護能力其知識產權、提交的時機和成功程度、監管申報的接受和批准。這些決定實際業績的因素中有許多超出了公司的控制或預測能力。

Readers should not unduly rely on these forward-looking statements, which are not a guarantee of future performance. There can be no assurance that forward looking statements will prove to be accurate as such forward looking statements involve known and unknown risks, uncertainties and other factors which may cause actual results or future events to differ materially from the forward-looking statements.

讀者不應過度依賴這些前瞻性陳述,這些陳述並不能保證未來的表現。無法保證前瞻性陳述會被證明是準確的,因爲此類前瞻性陳述涉及已知和未知的風險、不確定性和其他因素,這些因素可能導致實際業績或未來事件與前瞻性陳述存在重大差異。

Although the forward-looking statements contained in the press release are based upon what management currently believes to be reasonable assumptions, the Company cannot assure prospective investors that actual results, performance or achievements will be consistent with these forward-looking statements.

儘管新聞稿中包含的前瞻性陳述基於管理層目前認爲的合理假設,但公司無法向潛在投資者保證實際業績、業績或成就將與這些前瞻性陳述一致。

All forward-looking statements are made as of the date hereof and are subject to change. Except as required by law, the Company assumes no obligation to update such statements.

所有前瞻性陳述均自本文發佈之日起作出,可能會發生變化。除非法律要求,否則公司沒有義務更新此類聲明。

For More Information:

欲了解更多信息:

1.866.THE.LASE (843-5273)
416.699.LASE (5273)

1.866..LASE (843-5273)
416.699.LASE (5273)

Kristina Hachey, CPA
Chief Financial Officer
khachey@theralase.com

克里斯蒂娜·哈奇,註冊會計師
首席財務官
khachey@theralase.com

SOURCE: Theralase Technologies Inc.

資料來源:Theralase Technologies


譯文內容由第三人軟體翻譯。


以上內容僅用作資訊或教育之目的,不構成與富途相關的任何投資建議。富途竭力但無法保證上述全部內容的真實性、準確性和原創性。
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