Pliant Therapeutics Announces Accelerated Bexotegrast Development Plan for the Treatment of Idiopathic Pulmonary Fibrosis
Pliant Therapeutics Announces Accelerated Bexotegrast Development Plan for the Treatment of Idiopathic Pulmonary Fibrosis
Pliant Therapeutics, Inc. (NASDAQ:PLRX), a clinical-stage biotechnology company and leader in the discovery and development of novel therapeutics for the treatment of fibrotic diseases, today announced the implementation of BEACON-IPF as a pivotal, adaptive Phase 2b/3 trial in patients with idiopathic pulmonary fibrosis (IPF). The adaptive design implementation, based on acceptance by the European Union (EU) and other global health authorities, will significantly shorten bexotegrast's late-stage development compared to a traditional Phase 3 trial. Bexotegrast is an oral, small molecule, dual-selective inhibitor of αvβ6 and αvβ1 integrins in clinical development for the treatment of IPF and primary sclerosing cholangitis (PSC).
Pliant Therapeutics, Inc. (NASDAQ:PLRX), a clinical-stage biotechnology company and leader in the discovery and development of novel therapeutics for the treatment of fibrotic diseases, today announced the implementation of BEACON-IPF as a pivotal, adaptive Phase 2b/3 trial in patients with idiopathic pulmonary fibrosis (IPF). The adaptive design implementation, based on acceptance by the European Union (EU) and other global health authorities, will significantly shorten bexotegrast's late-stage development compared to a traditional Phase 3 trial. Bexotegrast is an oral, small molecule, dual-selective inhibitor of αvβ6 and αvβ1 integrins in clinical development for the treatment of IPF and primary sclerosing cholangitis (PSC).
Pliant Therapeutics, Inc.(納斯達克股票代碼:PLRX)是一家臨床階段的生物技術公司,也是纖維化疾病治療新療法發現和開發領域的領導者。該公司今天宣佈實施BEACON-IPF,這是一項針對特發性肺纖維化(IPF)患者的關鍵性適應性2b/3期試驗。與傳統的3期試驗相比,基於歐盟(EU)和其他全球衛生當局接受的自適應設計的實施將顯著縮短bexotegrast的後期開發時間。Bexotegrast是一種口服、小分子、雙選擇性的αvβ6和αvβ1整合素抑制劑,用於治療IPF和原發性硬化性膽管炎(PSC)。
譯文內容由第三人軟體翻譯。
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