PDS Biotech Announces Interim Safety and Immune Response Data From Phase 1/2 Clinical Trial Evaluating Novel Antibody Drug Conjugate PDS0301 Combined With Docetaxel to Treat Metastatic Prostate Cancer
PDS Biotech Announces Interim Safety and Immune Response Data From Phase 1/2 Clinical Trial Evaluating Novel Antibody Drug Conjugate PDS0301 Combined With Docetaxel to Treat Metastatic Prostate Cancer
PDS Biotechnology Corporation (NASDAQ:PDSB) (PDS Biotech or the Company), a clinical-stage immunotherapy company developing a growing pipeline of targeted cancer immunotherapies and infectious disease vaccines based on the Company's proprietary T cell activating platforms, today announced interim safety and immune response data for the first-in-human Phase 1/2 clinical trial evaluating PDS0301, a novel investigational tumor-targeting, antibody-conjugated Interleukin 12, in combination with current standard-of-care (SOC) chemotherapy, docetaxel, to treat metastatic castration sensitive (mCSPC) and castration resistant (mCRPC) prostate cancer. The data will be featured in an oral presentation by Ravi A. Madan, MD, Head, Prostate Cancer Clinical Research Section, Genitourinary Malignancies Branch, Center for Cancer Research of the National Cancer Institute, an Institute of the National Institutes of Health, at the 11th Annual Meeting of the International Cytokine & Interferon Society (Cytokines 2023) in Athens, Greece.
PDS Biotechnology Corporation(納斯達克股票代碼:PDSB)(PDS Biotechnology 或 “公司”)是一家臨床階段的免疫療法公司,基於公司專有的 T 細胞激活平台,正在開發越來越多的靶向癌症免疫療法和傳染病疫苗產品線。該公司今天宣佈了首項評估 PDS0301 的人體1/2期臨床試驗的臨時安全和免疫反應數據,這是一項新的研究性腫瘤靶向、抗體結合的白介素12,與目前的標準化療 (SOC) 化療多西他賽聯合使用,用於治療轉移性閹割敏感 (mcSPC) 和閹割耐藥性 (mcRPC) 前列腺癌。這些數據將在希臘雅典舉行的國際細胞因子與干擾素學會第11屆年會(Cytokines 2023)上由美國國立衛生研究院下屬的國家癌症研究所癌症研究中心泌尿生殖系統惡性腫瘤處前列腺癌臨床研究科主任拉維·馬丹醫學博士的口頭陳述。
譯文內容由第三人軟體翻譯。