Sweet Earth Completes Pivotal in Vitro Testing of Active Ingredients
Sweet Earth Completes Pivotal in Vitro Testing of Active Ingredients
The Navco study concludes that optimal skin permeability of Sweet Earth CBD cream occurs within 0.5 to 4 hours of applications; therefore, the active ingredient (CBD) reaches its maximum effectiveness when applied topically within 3 hours. This suggests that topical administration is an ideal method to deliver CBD cream for therapeutic purposes, such as muscle rubs and skin hydration creams. Vancouver, British Columbia--(Newsfile Corp. - July 11, 2022) - Sweet Earth Holdings Corp. (CSE: SE) (FSE: 1KZ1) (OTCQB: SEHCF) ("Sweet Earth" the "Company") is pleased to announce results from its In Vitro Release Testing ("IVRT") Product Research Program (the "R&D Program") that is being conducted with NAVCO Pharmaceuticals Limited ("Navco"), an accredited laboratory located in Burlington, Ontario. The purpose of the Company's R&D Program is to maximize efficacy of its CBD skincare and body care products and to assure validation of claimed benefits. IVRT of Sweet Earth products included investigating the accumulative absorption of CBD through the skin by determining time and quantity required to reach maximum absorption of CBD using Franz Cell diffusion apparatus[1]. Understanding absorption rates is very important, especially given that the CBD-product sector is somewhat unregulated, and the Company continues to focus on becoming an industry leader.
温哥華，不列顛哥倫比亞省-(Newsfile Corp.-2022年7月11日)-Sweet Earth Holdings Corp.(CSE：SE)(FSE：1KZ1) (OTCQB：SEHCF) ("甜蜜的地球“The”公司“)很高興地宣佈其體外釋放測試的結果(”IVRT“)產品研究計劃(”研發計劃“)正在與NAVCO製藥有限公司(”NAVCO位於安大略省伯靈頓的認可實驗室。該公司研發計劃的目的是使其CBD護膚和身體護理產品的功效最大化，並確保所聲稱的益處得到證實。甜土產品的IVRT包括調查CBD通過皮膚的累積吸收，方法是使用Franz Cell擴散儀確定達到CBD最大吸收所需的時間和數量[1]。瞭解吸收率非常重要，特別是考慮到CBD產品部門在某種程度上不受監管，該公司繼續專注於成為行業領先者。
Results from IVRT show that CBD permeability of Sweet Earth Products begins within 30 minutes, and steadily increases to reach the maximum absorption at 3 hours. Therefore, the topical administration of CBD semisolid emulsion, from Sweet Earth, can be an optimal choice for delivering significant quantity of CBD for therapeutic purposes. Meta-analysis of selected publications indicated therapeutics potential in arthritis, muscle recovery, muscle training and performance on exercise.
IVRT結果表明，甜土產品的CBD滲透性在30min內開始增加，並在3h達到最大吸收。因此，局部使用來自Sweet Earth的CBD半固體乳劑是為治療目的提供大量CBD的最佳選擇。對選定出版物的薈萃分析表明，在關節炎、肌肉恢復、肌肉訓練和運動表現方面具有治療潛力。
Topical/transdermal CBD delivery has advantages over other routes since it is the preferred utilization route for dermatologists and patients, due to its localized effect of a specific area while not affecting other organs[2]. Despite the extra focus on CBD as a topical treatment, there is very limited research on the permeability of CBD through skin, resulting in lack of the experiential evidence on CBD permeability of cosmetic products.
局部/經皮CBD給藥比其他途徑更有優勢，因為它是皮膚科醫生和患者的首選利用途徑，因為它對特定區域的局部作用而不影響其他器官。[2]。儘管CBD作為一種外用治療方法受到了極大的關注，但關於CBD對皮膚的滲透性的研究非常有限，導致缺乏關於化粧品CBD滲透性的經驗證據。
The Navco study concludes that optimal skin permeability of Sweet Earth CBD cream occurs within 0.5 to 4 hours of applications; therefore, the active ingredient (CBD) reaches its maximum effectiveness when applied topically within 3 hours. This suggests that topical administration is an ideal method to deliver CBD cream for therapeutic purposes, such as muscle rubs and skin hydration creams.
NAVCO的研究得出結論，甜蜜地球CBD霜的最佳皮膚滲透性在使用後0.5至4小時內出現；因此，當局部使用時，有效成分(CBD)在3小時內達到最佳效果。這表明，局部給藥是提供CBD霜的理想方法，用於治療目的，如肌肉按摩和皮膚保濕霜。
Sweet Earth is in the process of expanding its retail base to include pharmaceutical focused distributors and has provided the results to key wholesale distributors.
甜蜜地球正在擴大其零售基礎，以包括專注於藥品的分銷商，並已將結果提供給主要的批發分銷商。
About Sweet Earth
關於甜蜜的地球
Corporate Website: .
公司網站：.
Sweet Earth is a vertically integrated "farm to shelf" hemp grower with a farm in Applegate, Oregon, that maintains a full line of hemp and CBD products for the US and global market. Its products combine CBD with herbal and organic ingredients, all of which are selected for their beneficial properties to soothe, rejuvenate, and reduce inflammation. In addition to high-end finished products, Sweet Earth prides itself on sustainability by minimizing the use of plastics in both production and packaging.
Sweet Earth是一家垂直整合的“從農場到貨架”的大麻種植商，在俄勒岡州的阿普爾蓋特設有一個農場，為美國和全球市場提供全線大麻和CBD產品。它的產品結合了CBD與草藥和有機成分，所有這些都是因為它們的有益特性而被挑選出來，以緩解、恢復活力和減少炎症。除了高端成品，甜蜜地球還以可持續發展為榮，在生產和包裝中儘量減少塑料的使用。
Sweet Earth maintains a portfolio of skin and body care products that includes facial products, men's, spa, hemp, and muscle products that are sold on its website, .
甜蜜地球擁有一系列皮膚和身體護理產品，包括面部產品、男士產品、水療、大麻和肌肉產品，這些產品在其網站上銷售。
Sweet Earth operates a proprietary online shopping portal for discerning pet owners offering pet treats comprised of high-quality ingredients, which are further enriched with CBD and Vitamin E. The treats are sold on its website: .
甜蜜地球運營着一個專有的在線購物門户網站，為有眼光的寵物主人提供由高質量成分組成的寵物美食，這些原料含有CBD和維生素E。這些美食在其網站上出售：.
Sweet Earth has created a line of CBD pre-rolls that are made from 100% naturally grown US hemp flower that is rich in non-intoxicating cannabinoids like CBD and cannabigerol ("CBG"). The pre-rolls are completely free of tobacco, nicotine, or additives. The pre-rolls are also rich in terpenes, like pinene, limonene and myrcene and are sold on its online portal,
甜蜜的地球創造了一系列CBD預卷，這些預卷是由100%自然生長的美國大麻花製成的，這種花富含CBD和大麻酚等不令人陶醉的大麻類化合物。CBG“)。預卷完全不含煙草、尼古丁或添加劑。預卷還富含萜烯、檸檬烯和月桂烯，並在其在線門户網站上出售，
ON BEHALF OF THE BOARD
我代表董事會
"Chris Cooper"
Chris Cooper, CFO and Director
《克里斯·庫珀》
克里斯·庫珀，董事首席財務官
For additional information contact: Chris Cooper / CFO and Director
Telephone: (604) 307-8290
Email: info@sweetearthcbd.com
欲瞭解更多信息，請聯繫：克里斯·庫珀/首席財務官和董事
電話：(604)307-8290
電子郵件：Info@SweetEarthcbd.com
Neither the Canadian Securities Exchange nor its regulation services provider accepts responsibility for the adequacy or accuracy of this release.
加拿大證券交易所及其監管服務提供商均不對本新聞稿的充分性或準確性承擔責任。
[1] Definition:
[1]定義：
[2] Mahmoudinoodezh, H., Telukutla, S. R., Bhangu, S. K., Bachari, A., Cavalieri, F., & Mantri, N. (2022). The Transdermal Delivery of Therapeutic Cannabinoids. Pharmaceutics, 14(2), 438.
[2]馬哈茂迪努德茲，H.，特魯庫特拉，S.R.，班古，S.K.，Bachari，A.，Cavalieri，F.，&Mantri，N.(2022)。治療性大麻素的經皮給藥。藥劑學，14(2)，438。
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