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Neuropathix, Inc. CEO Issues New Letter to Shareholders; Updates Market on Milestones in Research and Funding

Neuropathix, Inc. CEO Issues New Letter to Shareholders; Updates Market on Milestones in Research and Funding

Neuropathix公司首席執行官向股東發出新信;向市場通報研究和資金方面的最新里程碑
Accesswire ·  2022/04/06 21:06

DOYLESTOWN, PA / ACCESSWIRE / April 6, 2022 / Neuropathix, Inc. ("Neuropathix" or the "Company") (OTCQB:NPTX), a socially responsible pain management life sciences company, announced today that its CEO Dean Petkanas has issued a letter to its shareholders, providing commentary on the Company's recently achieved milestones, updates on its research and financial positioning. Please see the contents of the letter below including a summary.

賓夕法尼亞州多伊爾斯敦/ACCESSWIRE/2022年4月6日/具有社會責任感的疼痛管理生命科學公司Neuropathix,Inc.(“Neuropathix”或“公司”)(場外交易市場代碼:NPTX)今天宣佈,其首席執行官迪恩·佩特卡納斯已致信股東,就公司最近取得的里程碑、研究和財務定位的最新情況發表評論。請看下面這封信的內容,包括摘要。

Summary:

摘要:

  • Neuropathix continues to experience shareholder base growth and further support from long-term investors, including a recent bridge financing.
  • In the past decade, pharmaceutical companies have been reluctant to re-address pain treatments following the opioids crisis. However, we see a change on the horizon.
  • Neuropathix has designated proprietary, cannabinoid-derivative compound KLS-13019 as lead drug candidate for the treatment of neuropathic pain, a viable alternative to opioids.
  • Neuropathix wholly owned subsidiary, Kannalife Sciences, Inc. received a $2.97 million grant from the National Institutes of Health HEAL program for IND enabling studies and the furtherment of its clinical program for KLS-13019.
  • The NIH grant was awarded based on a priority impact score of 20 by peer reviewing scientists, denoting the exceptional and novel potential of KLS-13019's non-addictive properties seen through advanced pre-clinical studies for the treatment of chemotherapy induced peripheral neuropathy (CIPN).
  • Neuropathix continues to move forward in preparation of an IND filing for the use of KLS-13019 in CIPN. The next two major steps in 2022 will be the successful completion of the first leg of commercial scale up and a drug discrimination study in animals.
  • Year two of the grant funding should enable the Company to move KLS-13019 into animal toxicity studies by early 2023, as the next steps towards IND submission with the US FDA.
  • Neuropathix繼續經歷股東基礎的增長和長期投資者的進一步支持,包括最近的過渡性融資。
  • 在過去的十年裏,製藥公司在阿片類藥物危機之後一直不願重新解決疼痛治療問題。然而,我們看到了地平線上的變化。
  • Neuropathix已指定專有大麻素衍生物化合物KLS-13019作為治療神經病理性疼痛的主要候選藥物,這是阿片類藥物的可行替代品。
  • Neuropathix的全資子公司KannaLife Science,Inc.從美國國立衞生研究院獲得297萬美元的贈款,用於IND使能研究和進一步推進其針對KLS-13019的臨牀計劃。
  • 美國國立衞生研究院的撥款是基於同行評審科學家的20分優先影響評分授予的,這表明了KLS-13019的非成癮特性的特殊和新的潛力,通過用於治療化療引起的周圍神經病變的高級臨牀前研究看到了這一潛力。
  • Neuropathix繼續向前推進,準備在CIPN中使用KLS-13019的IND申請。2022年的下兩個主要步驟將是成功完成商業放大的第一階段和在動物身上進行藥物歧視研究。
  • 第二年的贈款資金將使該公司能夠在2023年初將KLS-13019納入動物毒性研究,作為向美國食品和藥物管理局提交IND的下一步。

To read the Letter to Shareholders in full, please visit:

要閲讀致股東的信的全文,請訪問:

Research reported in this publication was supported by the National Institute Of Neurological Disorders And Stroke (NINDS) of the National Institutes of Health (NIH) under Award Number R42NS120548.

本出版物中報道的研究由美國國立衞生研究院(NIH)的國家神經疾病和中風研究所(NINDS)支持,獲獎號為R42NS120548。

The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

內容完全由作者負責,不一定代表美國國立衞生研究院的官方觀點。

About KLS-13019

關於KLS-13019

KLS-13019 is Neuropathix patented lead clinical compound for the potential treatment of a range of inflammatory, neurodegenerative and neuropathic pain disorders, beginning with chemotherapy-induced peripheral neuropathy (CIPN). KLS-13019 is a monotherapeutic non-opioid cannabinoid derivative that has been shown to prevent and reverse neuropathic pain in pre-clinical animal studies. KLS-13019 has not been reviewed or approved for patient use by the U.S. Food and Drug Administration (FDA) or any other healthcare authority in the world. Its safety and efficacy have not been confirmed by FDA-approved research.

KLS-13019是Neuropathix獲得專利的領先臨牀化合物,用於潛在地治療一系列炎性、神經退行性和神經病理性疼痛疾病,從化療引起的周圍神經病變開始。KLS-13019是一種單一治療的非阿片類大麻衍生物,在臨牀前動物研究中已被證明可以預防和逆轉神經病理性疼痛。KLS-13019尚未經過美國食品和藥物管理局或世界上任何其他醫療機構的審查或批准用於患者。其安全性和有效性尚未得到FDA批准的研究的證實。

About Neuropathix, Inc.

關於Neuropathix公司

Neuropathix is a biopharmaceutical company focused on the research and development of a pipeline of next generation, socially responsible pain management and neuroprotective therapeutics to treat patients with significant unmet medical needs. Over the past ten years, Neuropathix has discovered, developed, and patented a global intellectual property estate, led by its lead clinical target, KLS-13019, as novel, new therapeutic agents designed to prevent and reverse neuropathic pain, reduce oxidative stress, and act as anti-inflammatory neuroprotectants. The Company's family of patented monotherapeutic molecules focuses on treating oxidative stress-related diseases, chronic pain management, and neurodegenerative disorders. The therapeutic targets include chemotherapy-induced peripheral neuropathy (CIPN), a chronic neuropathy caused by toxic chemotherapeutic agents; hepatic encephalopathy (HE), a neurotoxic brain-liver disorder caused by excessive concentrations of ammonia and ethanol in the brain; mild traumatic brain injury (mTBI), a disorder associated with single and repetitive impact injuries; and chronic traumatic encephalopathy (CTE), a disease associated with highly repetitive impact injuries in professional and amateur sports. Neuropathix conducts its research and development efforts at the Pennsylvania Biotechnology Center of Bucks County in Doylestown, PA. For more information about Neuropathix, visit and the Company's Twitter page at @neuropathix.

Neuropathix是一家生物製藥公司,專注於研究和開發下一代、對社會負責的疼痛管理和神經保護療法的管道,以治療有重大未得到滿足的醫療需求的患者。在過去的十年裏,Neuropathix已經發現、開發和申請了全球知識產權,以其主要臨牀目標KLS-13019為首,作為新型治療藥物,旨在預防和逆轉神經病理性疼痛,減少氧化應激,並作為抗炎神經保護劑。該公司的專利單一治療分子系列專注於治療氧化應激相關疾病、慢性疼痛管理和神經退行性疾病。治療的目標包括化療所致的周圍神經病(CIPN),這是一種由有毒化療藥物引起的慢性神經病變;肝性腦病(HE),一種因腦內氨和乙醇濃度過高而引起的神經毒性腦-肝疾病;輕度創傷性腦損傷(MTBI),一種與單次和重複撞擊損傷有關的疾病;以及慢性創傷性腦病(CTE),一種與職業和業餘運動中高度重複的撞擊損傷有關的疾病。Neuropathix在賓夕法尼亞州多伊爾斯敦的巴克斯縣賓夕法尼亞州生物技術中心進行研究和開發工作。欲瞭解有關Neuropathix的更多信息,請訪問網站和該公司的推特頁面:@Neuropathix。

Forward-Looking Statements

前瞻性陳述

This press release may contain certain forward-looking statements and information, as defined within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934 and is subject to the Safe Harbor created by those sections. This press release contains statements about expected future events, the Company's business plan, plan of operations, the viability of the Company's drug candidates, the targeted beneficial effects of KLS-13019, the Company's position, and/or financial results that are forward-looking in nature and subject to risks and uncertainties. Such forward-looking statements, by definition, involve risks and uncertainties. The Company does not sell or distribute any products that are in violation of the United States Controlled Substances Act.

本新聞稿可能包含1933年證券法第27A節和1934年證券交易法第21E節所界定的某些前瞻性陳述和信息,並受這兩節所創造的安全港的約束。本新聞稿包含有關預期的未來事件、公司的業務計劃、運營計劃、公司候選藥物的可行性、KLS-13019的目標有益效果、公司的狀況和/或財務結果的陳述,這些陳述具有前瞻性,受風險和不確定因素的影響。根據定義,此類前瞻性陳述包含風險和不確定因素。本公司不銷售或分銷任何違反《美國管制物質法》的產品。

CONTACTS:

聯繫人:

Public Relations:
Kyle Porter
CMW Media
P: 858-221-8001
E: nptx@cmwmedia.com

公共關係:
凱爾·波特
CMW媒體
P: 858-221-8001
郵箱:nptx@cmwmedia.com

Investor Relations:
Louie Toma
Managing Director
CORE IR
P: 516-222-2560
E: louie@coreir.com

投資者關係:
路易·託馬
經營董事
核心紅外光譜
P: 516-222-2560
E:Louie@coreir.com

SOURCE: Neuropathix, Inc.

資料來源:Neuroath,Inc.


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