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Oncology Pharma, Inc. and Regen BioPharma, Inc. Announce Intent to Jointly Fast Track Development of Modified mRNA anti-Cancer Vaccine

Oncology Pharma, Inc. and Regen BioPharma, Inc. Announce Intent to Jointly Fast Track Development of Modified mRNA anti-Cancer Vaccine

腫瘤學制藥公司和Regen BioPharma公司宣佈有意聯合快速開發改良的mRNA抗癌疫苗
Accesswire ·  2022/02/14 20:36

SAN FRANCISCO, CA / ACCESSWIRE / February 14, 2022 / Oncology Pharma, Inc. ("The Company") (OTC PINK:ONPH) and Regen BioPharma, Inc. (OTC PINK:RGBP) and (OTC PINK:RGBPP): announced that they intend to work jointly to fast track the development of therapeutic uses related to treatment in humans with pancreatic cancer of Regen's patented ANTIGEN SPECIFIC MRNA CELLULAR CANCER VACCINES ("MRNA Vaccines").

加利福尼亞州舊金山/ACCESSWIRE/2022年2月14日/腫瘤製藥公司(“本公司”)(OTC PINK:ONPH)和Regen BioPharma,Inc.(OTC PINK:RGBP)和(OTC PINK:RGBPP)宣佈,他們打算共同努力,快速開發與治療胰腺癌相關的Regen專利抗原特異性mRNA細胞癌疫苗(“mRNA疫苗”)。

In April of 2021 ONPH was granted an exclusive right and license for the development and commercialization of the MRNA Vaccines for the treatment in humans of pancreatic cancer.

2021年4月,ONPH獲得了用於人類胰腺癌治療的mRNA疫苗的獨家開發和商業化的權利和許可證。

The current intent is that IND ("Investigational New Drug Application") enabling studies are to be commenced and completed with Regen providing the scientific expertise, laboratory access and modified mRNA and cellular manufacturing needed to complete the studies and ONPH providing the required financing.

目前的目的是啟動和完成IND(“研究性新藥申請”)的研究,Regen提供完成研究所需的科學專門知識、實驗室准入和修改後的mRNA和細胞製造,ONPH提供所需的資金。

This patented technology (patent issued in Aug, 2021) is a cellular vaccine that uses a modified mRNA molecule expressing peptides of Survivin which are exposed to dendritic cells. These dendritic cells are then matured and infused into the cancer patient's circulation where they are expected to hone in on the cancer and destroy it. There are currently several clinical trials ongoing around the world using Survivin as a vaccine for multiple different cancers which further supports this approach.

這項專利技術(專利發佈於2021年8月)是一種細胞疫苗,它使用一種修飾的mRNA分子表達Survivin多肽,使其暴露於樹突狀細胞。然後,這些樹突狀細胞成熟並注入癌症患者的循環中,在那裏它們有望磨練癌症並摧毀它。目前,世界各地正在進行幾項臨牀試驗,使用Survivin作為多種不同癌症的疫苗,這進一步支持了這一方法。

"I am very excited to get our newly patented modified mRNA technology advanced to the point whereby an IND can be submitted to the FDA," says David Koos, CEO and Chairman of Regen. "I expect that once our experimental protocols are set up, the path to a cleared IND from the FDA will be straightforward."

Regen公司首席執行官兼董事長David Koos説:“我非常高興能讓我們新獲得專利的改良mRNA技術進步到可以向FDA提交IND的地步。”我預計,一旦我們的實驗方案建立起來,從FDA獲得批准的IND的道路將是直截了當的。“

"Due to the COVID pandemic, the FDA now understands the excellent safety profile of modified mRNA technology," says the CEO of ONPH. "We believe this technology which targets Survivin and uses the patient's own immune system to kill their tumors will have the same success in treating pancreatic cancer that the CAR-T cell approach is having in liquid tumors."

ONPH的首席執行官説:“由於COVID的流行,FDA現在瞭解改良的mRNA技術的極好的安全性。”“我們相信,這項針對Survivin並利用患者自身免疫系統殺死腫瘤的技術,在治療胰腺癌方面將取得與CAR-T細胞方法治療液體腫瘤相同的成功。”

The initiation and completion of the abovementioned is contingent upon several factors including, but not limited to, the execution of one or more mutually acceptable definitive agreements between the parties and securing of adequate financing. Although the parties are confident that any and all contingencies can be satisfied no assurance can be given that any such agreements shall be executed or, if executed, shall not contain terms and conditions materially different from the terms and conditions currently contemplated or that adequate financing can be secured.

上述協議的啟動和完成取決於幾個因素,包括但不限於雙方是否簽署了一項或多項雙方均可接受的最終協議,以及是否獲得足夠的資金。儘管雙方確信可以滿足任何和所有或有事項,但不能保證任何此類協議將被執行,或如果執行,不得包含與目前設想的條款和條件有實質性不同的條款和條件,也不能保證能獲得足夠的融資。

ABOUT ONCOLOGY PHARMA, INC.

腫瘤學制藥公司簡介

ONCOLOGY PHARMA, INC. (OTC PINK:ONPH) (the 'Company') is currently engaging in research and development of therapeutics for oncology and prides itself for having a world-class Advisory Board that keeps the Company in the forefront of developing technologies in cancer research, biotechnology, and healthcare.

腫瘤學制藥公司(Oncology Pharma,Inc.)OTC PINK:ONPH)(“本公司”)目前正在從事腫瘤學治療藥物的研究和開發,併為擁有一個世界級的顧問委員會而感到自豪,該委員會使本公司在癌症研究、生物技術和醫療保健領域的技術開發處於領先地位。

About Regen BioPharma Inc.:

Regen BioPharma公司簡介:

Regen BioPharma Inc. is a publicly traded biotechnology company (OTCQB: RGBP) and (OTCQB: RGBPP). The Company is focused on the immunology and immunotherapy space. The Company is focused on rapidly advancing novel technologies through pre-clinical and Phase I/ II clinical trials. Currently, the Company is focused on small molecule therapies for treating cancer and autoimmune disorders. Additional information on Regen BioPharma is available at

Regen BioPharma Inc.是一家公開上市的生物技術公司(場外交易市場代碼:RGBP)和(場外交易市場代碼:RGBPP)。該公司專注於免疫學和免疫治療領域。該公司專注於通過臨牀前和I/II期臨牀試驗快速推進新技術。目前,該公司專注於治療癌症和自身免疫性疾病的小分子療法。有關Regen BioPharma的更多信息,請訪問:

Disclaimer: This news announcement may contain forward-looking statements. Forward-looking statements are inherently subject to risks and uncertainties, some of which cannot be predicted or quantified. Future events and actual results could differ materially from those set forth in, contemplated by, or underlying the forward-looking statements. The risks and uncertainties to which forward looking statements are subject include, but are not limited to, the effect of government regulation, competition and other material risks.

免責聲明:本新聞公告可能包含前瞻性陳述。前瞻性陳述固有地受到風險和不確定性的影響,其中一些風險和不確定性是無法預測或量化的。未來的事件和實際結果可能與前瞻性陳述中陳述的、預期的或潛在的大不相同。前瞻性陳述所涉及的風險和不確定因素包括但不限於政府監管、競爭和其他重大風險的影響。

FORWARD LOOKING STATEMENTS

前瞻性陳述

Certain of the matters discussed in this announcement contain forward-looking statements that involve material risks to and uncertainties in the Company's business that may cause actual results to differ materially from those anticipated by the statements made herein. Such risks and uncertainties include risks related to licensing arrangements and joint ventures, including the need to negotiate the definitive agreements for the relationships; possible failure to realize anticipated benefits of business relationships, and costs of providing funding to these business relationships. Other risks and uncertainties relating to the Company include, among other things, current negative operating cash flows and a need for additional funding to finance our operating plan; the terms of any further financing, which may be highly dilutive and may include onerous terms; unexpected costs and operating deficits, and lower than expected sales and revenues; uncertain willingness and ability of customers to adopt new technologies and other factors that may affect further market acceptance; adverse economic conditions; adverse results of any legal proceedings; the volatility of our operating results and financial condition; inability to attract or retain qualified senior management personnel, including sales and marketing personnel; our ability to establish and maintain the proprietary nature of our technology through the patent process, as well as our ability to possibly license from others patents and patent applications necessary to develop products; the Company's ability to implement its long range business plan for various applications of its technology; the Company's ability to enter into agreements with any necessary marketing and/or distribution partners and with any strategic or joint venture partners; the impact of competition; the obtaining and maintenance of any necessary regulatory clearances applicable to applications of the Company's technology; management of growth; and, other risks and uncertainties. This is not a solicitation to buy or sell securities and does not purport to be an analysis of the Company's financial position.

本公告中討論的某些事項包含前瞻性陳述,這些陳述涉及公司業務的重大風險和不確定性,可能導致實際結果與本文所作陳述預期的結果大不相同。這些風險和不確定因素包括與許可安排和合資企業有關的風險,包括需要就關係的最終協議進行談判;可能無法實現商業關係的預期利益,以及為這些商業關係提供資金的成本。與本公司有關的其他風險和不確定因素包括:當前運營現金流為負,需要額外資金為我們的運營計劃提供資金;任何進一步融資的條款,可能具有高度稀釋作用,可能包括苛刻的條款;意想不到的成本和運營赤字,以及低於預期的銷售和收入;客户採用新技術的意願和能力不確定,以及其他可能影響進一步市場接受度的因素;不利的經濟狀況;任何法律訴訟的不利結果;我們的經營業績和財務狀況的波動;無法吸引或留住合格的高級管理人員,包括銷售和市場營銷。我們通過專利過程建立和維護我們技術的專有性質的能力, 以及我們可能從其他公司獲得開發產品所需的專利和專利申請許可的能力;公司實施其技術各種應用的長期業務計劃的能力;公司與任何必要的營銷和/或分銷合作伙伴以及與任何戰略或合資夥伴簽訂協議的能力;競爭的影響;獲得和保持適用於公司技術應用的任何必要的監管許可;增長管理;以及其他風險和不確定因素。這不是買賣證券的徵集,也不是對公司財務狀況的分析。

CONTACTS:

聯繫人:

For additional information, please contact the Oncology Pharma at:

如需更多信息,請與腫瘤學制藥公司聯繫,網址為:

One Sansome Street, Suite 3500
San Francisco, CA 94104
Phone: 415-869-1038
Fax: 415-946-8801
website:
email: info@oncology-pharma.com

桑瑟姆街一號,套房3500
加利福尼亞州舊金山,郵編:94104
電話:415-869-1038
傳真:415-946-8801
網站:
電子郵件:info@oncology-pharma.com

SOURCE: Oncology Pharma Inc.

資料來源:腫瘤學制藥公司(Oncology Pharma Inc.)


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