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Reported Earlier, Legend Biotech CARVYKTI Delivers Improved MRD Negativity And Overall Survival Benefits In Phase 3 CARTITUDE-4 Study

Reported Earlier, Legend Biotech CARVYKTI Delivers Improved MRD Negativity And Overall Survival Benefits In Phase 3 CARTITUDE-4 Study

早前報道,傳奇生物CARVYKTI在三期CARTITUDE-4研究中顯示出改善的微小殘留病陰性率和總體生存益處。
Benzinga ·  12/10 15:17
  • 89 percent of evaluable patients achieved minimal residual disease (MRD) negativity with CARVYKTI after three-year follow-up in CARTITUDE-4 study; the majority in less than 2 months
  • Results add to the overall survival (OS) benefit recently reported making CARVYKTI the first and only cell therapy to significantly extend OS versus standard therapies in multiple myeloma
  • Landmark Phase 3 CARTITUDE-4 study data featured as an oral presentation at the 66th American Society of Hematology (ASH) Annual Meeting and Exposition
  • 在CARTITUDE-4研究中,經過三年跟蹤,89%的可評估患者在使用CARVYKTI後達到了微小殘留病(MRD)陰性;大多數患者在不到2個月內達成這一結果。
  • 結果補充了最近報告的總體生存(OS)益處,證明CARVYKTI是首個也是唯一一個在多發性骨髓瘤中相比標準療法顯著延長OS的電芯療法。
  • 作爲口頭報告,CARTITUDE-4的里程碑III期研究數據在第66屆美國血液學會(ASH)年會和博覽會上進行了展示。

譯文內容由第三人軟體翻譯。


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