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Protagonist Therapeutics to Host Conference Call to Announce an Oral Peptide IL-17 Antagonist Development Candidate

Protagonist Therapeutics to Host Conference Call to Announce an Oral Peptide IL-17 Antagonist Development Candidate

Protagonist therapeutics 將召開電話會議,宣佈一種口服肽IL-17拮抗劑開發候選藥物
Accesswire ·  11/19 20:30

Webcast and conference call to be held be on Thursday, November 21st at 4:30 pm ET, dial in information below

網絡直播和電話會議將於11月21日星期四下午4:30在東部時間舉行,以下是撥入信息

NEWARK, CA / ACCESSWIRE / November 19, 2024 / Protagonist Therapeutics, Inc. ("Protagonist" or the "Company") today announced that the company will host a conference call and webcast to announce its oral peptide IL-17 antagonist development candidate and to share in vitro and pre-clinical proof-of-concept study results.

加利福尼亞州紐瓦克 / ACCESSWIRE / 2024年11月19日 / Protagonist Therapeutics公司("主角"或"公司")今天宣佈,該公司將舉辦電話會議和網絡直播,宣佈其口服肽IL-17拮抗劑開發候選藥物,並分享體外和臨床前概念研究結果。

Conference Call and Webcast Details
The dial-in numbers for Protagonist's investor update on Thursday, November 21st at 4:30 pm ET are:

電話會議和網絡直播細節
Protagonist投資者更新的撥入號碼爲東部時間11月21日下午4:30:

US-based Investors: 1-877-407-0752
International Investors: 1-201-389-0912
Conference Call ID: 13750274

美國投資者:1-877-407-0752
國際投資者:1-201-389-0912
電話會議ID:13750274

The webcast link for the event can be found here:

活動的網絡直播鏈接在這裏找到:

A replay of the presentation will be available on the Company's Investor Relations Events and Presentations webpage following the event.

演示的重播將在公司的投資者關係活動和演示網頁上在活動結束後提供。

About Protagonist
Protagonist Therapeutics is a late-stage development biopharmaceutical company. Two novel peptides derived from Protagonist's proprietary discovery platform are currently in advanced Phase 3 clinical development, with New Drug Application submissions to the FDA potentially in 2025. Icotrokinra (JNJ-2113, formerly PN-235), is the first targeted oral peptide designed to selectively block the IL-23 receptor,which underpins the inflammatory response in moderate-to-severe plaque PsO and other IL-23-mediated diseases. Icotrokinra binds to the IL-23 receptor with single-digit picomolar affinity and demonstrated potent, selective inhibition of IL-23 signaling in human T cells. Icotrokinra is licensed to Johnson & Johnson and is currently in Phase 3 development for psoriasis and is nearing completion of Phase 2b development for ulcerative colitis. Following icotrokinra's joint discovery by Protagonist and Johnson & Johnson scientists pursuant to the companies' IL-23R collaboration, Protagonist was primarily responsible for development of icotrokinra through Phase 1, with Johnson & Johnson assuming responsibility for development in Phase 2 and beyond. Rusfertide, a mimetic of the natural hormone hepcidin, is currently in Phase 3 development for the rare blood disorder polycythemia vera. Rusfertide is being co-developed and will be co-commercialized with Takeda Pharmaceuticals pursuant to a worldwide collaboration and license agreement entered into in 2024 under which the Company remains primarily responsible for development through NDA filing. The Company also has a number of pre-clinical stage oral drug discovery programs addressing clinically and commercially validated targets, including IL-17, hepcidin mimetic, and anti-obesity programs.

關於主角
Protagonist Therapeutics是一家處於後期開發階段的生物製藥公司。兩種新型肽來自Protagonist的專有發現平台,目前正在進行先進的第3階段臨床開發,預計將於2025年向FDA提交新藥申請。Icotrokinra(JNJ-2113,原名PN-235),是首個定向口服肽,旨在選擇性地阻斷IL-23受體,這是中-重度斑塊病和其他IL-23介導的疾病的炎症反應基礎。Icotrokinra以個位數皮摩爾親和力結合IL-23受體,並在人類T細胞中表現出對IL-23信號通路的有效、選擇性抑制。Icotrokinra已授權給強生公司,目前正處於第3階段爲牛皮癬進行開發,並且即將完成第20億期爲潰瘍性結腸炎進行開發。在Protagonist和強生公司的IL-23R合作框架下,Icotrokinra由共同發現,Protagonist主要負責通過第1階段開發Icotrokinra,而強生公司則承擔第2階段及以後的開發責任。Rusfertide是天然激素肝鐵蛋白的類擬物,目前正在進行罕見血液疾病紅細胞增多症的第3階段開發。Rusfertide正在與武田製藥合作開發,並將根據2024年達成的全球合作和許可協議進行共同商業化,根據該協議,公司主要負責通過NDA提交進行開發。公司還有許多處於臨床前階段的口服藥物發現項目,涉及臨床和商業驗證的靶點,包括IL-17,肝鐵蛋白類擬物和抗肥胖項目。

More information on Protagonist, its pipeline drug candidates and clinical studies can be found on the Company's website at .

有關Protagonist,其管道藥物候選和臨床研究的更多信息可在該公司的網站上找到。

Investor Relations Contact
Corey Davis, Ph.D.
LifeSci Advisors
+1 212 915 2577
cdavis@lifesciadvisors.com

投資者關係聯繫方式
Corey Davis,博士。
LifeSci顧問
+1 212 915 2577
cdavis@lifesciadvisors.com

Media Contact
Virginia Amann, Founder/CEO
ENTENTE Network of Companies
virginiaamann@ententeinc.com

媒體聯繫
Virginia Amann,創始人/首席執行官
ENTENTE公司網絡
virginiaamann@ententeinc.com

SOURCE: Protagonist Therapeutics

資料來源:protagonist therapeutics


譯文內容由第三人軟體翻譯。


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