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Bionano Announces Publication Shows That OGM Can Resolve Translocation Partners Involving MYC In Multiple Myeloma More Effectively Than Current Methods

Bionano Announces Publication Shows That OGM Can Resolve Translocation Partners Involving MYC In Multiple Myeloma More Effectively Than Current Methods

Bionano宣佈的出版物顯示,OGm能夠比當前方法更有效地解決涉及多發性骨髓瘤中MYC的易位夥伴。
Benzinga ·  10/24 20:16
  • Publication shows that OGM can resolve translocation partners involving MYC in multiple myeloma (MM) more effectively than current methods
  • The release of compelling data in MM underscores the potential for wider adoption and use of OGM across all blood cancers as an alternative to traditional methods like karyotyping and fluorescence in-situ hybridization (FISH)
  • 研究表明,OGm可以比當前方法更有效地解決涉及多發性骨髓瘤(MM)中MYC的易位伴侶。
  • Mm中發佈的令人信服的數據凸顯出OGm在所有血液癌症中的潛力,作爲傳統方法(如核型分析和熒光原位雜交(FISH))的替代選擇。

SAN DIEGO, Oct. 24, 2024 (GLOBE NEWSWIRE) -- Bionano Genomics, Inc. (NASDAQ:BNGO) today announced the publication in Blood Cancer Journal by a group of researchers at the Korea College of Medicine in South Korea showing that optical genome mapping (OGM) can resolve rearrangements in the MYC gene in multiple myeloma (MM), which represent highly actionable biomarkers in cancer. MM accounts for 1.3% of all malignancies and 12% of all hematologic cancers. Among the hallmark genetic abnormalities in MM are rearrangements involving the MYC gene, a potent oncogene which encodes a protein that functions as a transcriptional regulator. The release of compelling data in MM underscores the potential for wider adoption and use of OGM across all blood cancers as an alternative to traditional methods like karyotyping and fluorescence in-situ hybridization (FISH).

2024年10月24日聖地亞哥訊(環球新聞社)- Bionano Genomics,Inc.(納斯達克:BNGO)今日宣佈韓國醫學院的一組研究人員在《血液癌症雜誌》上發表文章,顯示光學基因組製圖(OGM)可以解決多發性骨髓瘤中MYC基因的重排,這代表着癌症中極具行動力的生物標誌物。多發性骨髓瘤佔所有惡性腫瘤的1.3%和所有血液系統癌症的12%。多發性骨髓瘤的核心遺傳異常之一是涉及MYC基因的重排,MYC是一種強效的癌基因,編碼一種作爲轉錄調節因子的蛋白質。Mm的引人注目數據發佈突顯了OGm在所有血液癌症中替代傳統方法(如核型分析和熒光原位雜交)的潛力和廣泛應用。

譯文內容由第三人軟體翻譯。


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