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Sanofi's Frexalimab Phase 2 Data Shows 41% Reduction In Key Biomarker Of Nerve Cell Damage In Relapsing MS; High-Dose Arm Demonstrates Significant Drop In Plasma Neurofilament Light Chain Levels After 48 Weeks; Supports Potential As High-Efficacy,...

Sanofi's Frexalimab Phase 2 Data Shows 41% Reduction In Key Biomarker Of Nerve Cell Damage In Relapsing MS; High-Dose Arm Demonstrates Significant Drop In Plasma Neurofilament Light Chain Levels After 48 Weeks; Supports Potential As High-Efficacy,...

賽諾菲安萬特的Frexalimab第2期數據顯示,複發性多發性硬化神經細胞損傷關鍵生物標誌物減少41%;高劑量組48周後血漿神經絲輕鏈水平顯著下降;支持其高功效的可能性,這是一種可自主使用、高效、很可能是一種全新的免疫類藥物。
Benzinga ·  06/28 23:41

Sanofi's Frexalimab Phase 2 Data Shows 41% Reduction In Key Biomarker Of Nerve Cell Damage In Relapsing MS; High-Dose Arm Demonstrates Significant Drop In Plasma Neurofilament Light Chain Levels After 48 Weeks; Supports Potential As High-Efficacy, Disease-Modifying Treatment; Phase 3 Studies Underway

賽諾菲安萬特的Frexalimab二期數據顯示,複發性多發性硬化症神經細胞損傷關鍵生物標誌物下降41%;高劑量組在48周後血漿神經絲輕鏈水平顯著下降;支持作爲高效治療、疾病修飾治療的潛力藥物;三期研究正在進行。

Frexalimab new phase 2 data showed reduction of key biomarker of nerve cell damage in relapsing MS

Frexalimab新的二期數據顯示,複發性多發性硬化症神經細胞損傷關鍵生物標誌物下降。

  • Frexalimab high-dose arm observed a 41% reduction in plasma neurofilament light chain (NfL) levels, a biomarker of nerve cell damage, after 48 weeks of treatment
  • Data support potential as a first-in-class, high-efficacy, and disease-modifying treatment for people with relapsing MS
  • Phase 3 studies of frexalimab in relapsing MS and non-relapsing secondary progressive MS (nrSPMS) are underway
  • Frexalimab高劑量組觀察到神經細胞損傷生物標誌物——血漿神經絲輕鏈(NfL)水平下降41%,治療48周後;
  • 數據支持作爲首個高效、疾病修飾性治療複發性多發性硬化症的治療方法。
  • Frexalimab 在複發性多發性硬化症和非複發性二級進行性多發性硬化症(nrSPMS)的三期研究正在進行中。

譯文內容由第三人軟體翻譯。


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