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PolyU Researchers Develop Novel Fungus-based Fat Replacer AkkMore to Prevent Obesity and Enhance Gut Health; Collaborates With Hotel ICON to Launch Reduced-fat Desserts to Promote Environmental Innovation in Food Industry

PolyU Researchers Develop Novel Fungus-based Fat Replacer AkkMore to Prevent Obesity and Enhance Gut Health; Collaborates With Hotel ICON to Launch Reduced-fat Desserts to Promote Environmental Innovation in Food Industry

理大研究人員開發以真菌爲基礎的新型脂肪替代劑AKKmore以預防肥胖和增強腸道健康;與ICON酒店合作推出減脂甜品以促進食品行業的環境創新
PR Newswire ·  05/22 21:58

HONG KONG, May 22, 2024 /PRNewswire/ -- In recent years, scientists have been actively exploring the potential of future foods, including using boundless microorganisms as substitutes for limited animal and plant resources. Among these microorganisms, the replacer of animal-derived fats is a research topic currently of very great interest. A research team from the Research Institute for Future Food (RiFood) and the Department of Food Science and Nutrition (FSN) of The Hong Kong Polytechnic University (PolyU) has successfully developed AkkMore, a novel fungus-based fat replacer which is effective in preventing obesity and metabolic diseases, enhancing gut health, modulating immune response and relieving anxiety. This replacer not only helps lower the calorific content of food, but also extends the shelf life of cream products. In the long term, it can reduce dairy consumption and food waste, providing innovative ESG (Environmental, Social and Governance) solutions in the food industry.

近年來,科學家一直在積極探索未來食品的潛力,包括使用無限的微生物作爲有限動植物資源的替代品。在這些微生物中,動物脂肪的替代物是目前非常感興趣的研究課題。香港理工大學未來食品研究所(RiFood)和食品科學與營養(FSN)系的一個研究團隊成功開發出Akkmor,這是一種新型的基於真菌的脂肪替代品,可以有效預防肥胖和代謝性疾病,增強腸道健康,調節免疫反應,緩解焦慮情緒。這種替代品不僅有助於降低食品的熱量含量,而且還可以延長奶油製品的保質期。長期來看,它可以減少乳製品消費和食品浪費,爲食品行業提供創新的ESG(環境,社會和治理)解決方案。

A PolyU research team led by Dr Gail CHANG, Core Member of RiFood and Research Assistant Professor of FSN together with Dr Amber CHIOU, Associate Director and Associate Professor of RiFood, and Associate Head of FSN has extracted the functional component of AkkMore from natural fungus to develop the replacer and has conducted three phases of animal experiments.

由香港理工大學未來食品研究所(RiFood)成員、食品科學與營養(FSN)系研究助理教授、RiFood主任Gail Chang博士和RiFood副主任、FSN副系主任、食品科學和營養學副教授Amberchiou博士一起,成功從真菌的天然來源提取了AkkMore的功能成分,開發了替代品,進行了三個階段的動物實驗。Chang博士表示:“這次合作證明了一項研究成果的成功轉化。今後,我們將進一步探索AkkMore配方在創新健康食品中的應用,並加大力度尋找更好功能的菌種,並規範培養過程。”一起Chang博士是2019年被香港理工大學GBA創新創業教育計劃錄取的博士後,並獲得了香港理工大學微基金的支持。此外,Chang博士還被選入香港科技園公司的Incu-Tech計劃,並在創業競賽中獲得多項獎勵。2020年,她與RiFood副主任、業務系助理教授金錦博士合作創建了以研究真菌生長機制爲重點的初創企業Bo InnoHealth Biotechnology。該公司獲得了香港理工大學創科啓動基金和多家天使基金的慷慨支持。

The study has found that mice which had been administered the AkkMore formula had a healthier gut microbiota with higher density of Akkermansia, lower Firmicutes/Bacteroidetes ratio, lighter adipose tissue and suppressed neuroinflammation when compared to the control group. This indicates the effectiveness of the formula in managing weight, enhancing gut health, modulating immune and metabolic diseases and relieving anxiety. This research won a Silver Medal at the 2022 International Exhibition of Inventions Geneva and its application for health benefits has entered patent substantive examination stage.

該研究發現,接受AkkMore配方治療的小鼠具有更健康的腸道菌群,Akkermansia密度更高,Firmicutes/Bacteroidetes比值更低,脂肪組織更輕,同時抑制神經炎症,與對照組相比,顯示出配方管理體重、提高腸道健康、調節免疫和代謝性疾病,減輕焦慮情緒的有效性。AkkermansiaAkkermansia

Making use of the thickening, emulsifying and stabilising properties of AkkMore, the team has developed Cream Mate, an AkkMore-based cream substitute. Cream Mate can be used in conjunction with traditional cream to reduce the amount of cream used in dessert. Not only does it decrease the fat and calorific content of food while maintaining the quality of taste and texture, but it also significantly extends the shelf life of cream-based products. In the long run, this could lead to reduced consumption of dairy products and food waste, reducing carbon emissions and profitability of production.

利用AkkMore的增稠、乳化和穩定性質,團隊開發了Cream Mate,一種基於AkkMore的奶油替代品。可以將Cream Mate與傳統奶油一起使用,減少甜品中奶油的使用量。它不僅可以降低食品的脂肪和熱量含量,同時還能保持食品的口感和質地,同時還可以顯著延長奶油製品的保質期。從長遠來看,這可能會導致對乳製品和食品浪費的減少,減少碳排放和生產的盈利能力

Dr Chang stated, "This collaboration is testament to the successful translation of a research outcome. Moving forward, we will further explore the application of AkkMore formula in innovative health foods and put greater efforts into identification of mushroom strains with better functions and standardisation of the cultivation process."

Chang博士說:“這次合作證明了一項研究成果的成功轉化。今後,我們將進一步探索AkkMore配方在創新健康食品中的應用,並加大各個方面的努力,尋找更好的菌種功能和規範培養過程。”Chang博士

PolyU is committed to the translation of research outcomes. Dr Chang was admitted to the PolyU GBA Startup Postdoc Programme in 2019 and has been granted support from the PolyU Micro Fund. As well as being selected for the Incu-Tech Programme of the Hong Kong Science and Technology Parks Corporation, Dr Chang has received a number of awards in entrepreneurial competitions. In 2020, she partnered with Dr Amber Chiou and Dr Jimmy JIN, Assistant Dean and Associate Professor of the Faculty of Business to establish Bo InnoHealth Biotechnology Company Limited, a start-up focusing on research into the growth mechanism of fungus and has received generous support from the PolyU Tech Launchpad Fund and multiple angel funds.

業務系助理教授、RiFood副主任、FSN副系主任、食品科學和營養學副教授Amberchiou博士金錦博士和頁面。業務系助理教授,香港理工大學商學院助理教授Jimmy Jin博士 香港理工大學商學院他們一起成立了Bo InnoHealth Biotechnology Company Limited,這是一家以研究真菌生長機制爲重點的初創企業。

Following the launch of supplement containing the AkkMore formula, the research team has collaborated with GREEN of Hotel ICON, the PolyU teaching and research hotel, whereby the hotel restaurant infuses Cream Mate in reduced-fat soft serve and desserts, and launch its new limited time "ForestFit Afternoon Tea With Japanese Fruit And Akkmore". Hotel ICON has commissioned a laboratory to test the nutritional components of soft serve in two formulae. The test showed that the total fat content of soft serve with AkkMore Cream Mate was less than 3% and was reduced by more than 80% when comparing with regular soft serve, and the total energy was also reduced by more than half. For more details, please visit the Hotel ICON website:

在推出含有AkkMore配方的保健品之後,研究團隊與香港理工大學教學研究酒店Hotel ICON的GREEN合作,酒店餐廳將Cream Mate注入低脂軟冰淇淋和甜點中,並推出了新的限時“ForestFit日本果腹午茶與Akkmore”。Hotel ICON已委託實驗室測試兩種配方軟冰淇淋的營養成分。實驗表明,含有AkkMore Cream Mate的軟冰淇淋總脂肪含量小於3%,與常規軟冰淇淋相比減少了80%以上,總能量也減少了一半以上。有關詳細信息,請訪問Hotel ICON的網站:

SOURCE The Hong Kong Polytechnic University

香港理工大學

譯文內容由第三人軟體翻譯。


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