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Enzolytics, Inc. Announces Execution of Non-Binding Term Sheet With the Special Purpose Acquisition Company Sagaliam Acquisition Corp. and Updates the Progress on the African Project

Enzolytics, Inc. Announces Execution of Non-Binding Term Sheet With the Special Purpose Acquisition Company Sagaliam Acquisition Corp. and Updates the Progress on the African Project

Enzolytics, Inc. 宣佈與特殊目的收購公司 Sagaliam Acquisition Corp. 執行不具約束力的條款表,並介紹非洲項目的最新進展
Accesswire ·  2023/04/17 19:05

COLLEGE STATION, TX / ACCESSWIRE / April 17, 2023 / Enzolytics, Inc. (OTC PINK:ENZC) (

德克薩斯州大學城/Accesswire/2023 年 4 月 17 日/ Enzolytics, Inc.(OTC PINK: ENZC)(

Enzolytics, Inc. (the "Company" or "ENZC"), a drug development biotech company, and Sagaliam Acquisition Corp. (NASDAQ: SAGA) ("Sagaliam"), a special purpose acquisition company ("SPAC"), announced today, April 17, 2023, they have executed a non-binding term sheet for the sale of Biogenysis, Inc. ("BGEN") and Virogentics, Inc. ("VIRO"), operating subsidiaries of Enzolytics. The value of the transaction is $250,000,000 The definitive agreement is being finalized with an expected closing date of May 19, 2023.

藥物開發生物技術公司Enzolytics, Inc.(“公司” 或 “ENZC”)和特殊目的收購公司(“SPAC”)Sagaliam Acquisition Corp.(“Sagaliam”)今天,即2023年4月17日宣佈,他們已經執行了出售Biogenysis, Inc.(“BGEN”)和Virogentics的不具約束力的條款表,Inc.(“VIRO”),Enzolytics的運營子公司。該交易的價值爲2.5億美元最終協議正在敲定中,預計截止日期爲2023年5月19日。

Under the terms of the agreement, BGEN and VIRO will become wholly owned subsidiaries of Sagaliam, currently trading on NASDAQ, and will adopt SAGA Scientific Holdings Corp. as the corporate name.

根據協議條款,BGEN和VIRO將成爲Sagaliam的全資子公司,目前在納斯達克上市,並將採用SAGA Scientific Holdings Corp. 作爲公司名稱。

The transaction, once completed, will provide BGEN and VIRO with significant additional capital to continue their development and expansion of existing and future technology platforms. In addition, Sagaliam expects to raise additional capital through a private investment in public equities ("PIPE"). The anticipated capital raise from the PIPE is expected to be primarily used by BGEN and VIRO to pay transaction-related expenses and fund the clinical trials of ITV-1, marketing of IPF Immune, production of fully human monoclonal antibodies (mAbs) and continued advancement in its proprietary technology involving the application of Artificial Intelligence (AI) in therapeutic discoveries and production.

該交易一旦完成,將爲BGEN和VIRO提供大量額外資金,以繼續開發和擴展現有和未來的技術平臺。此外,薩加拉姆預計將通過私人投資公募股權(“PIPE”)籌集更多資金。預計PIPE籌集的資金將主要由BGEN和VIRO用於支付交易相關費用和資助 ITV-1 的臨牀試驗、IPF Immune 的營銷、全人源單克隆抗體(mAB)的生產以及其涉及在治療發現和生產中應用人工智能(AI)的專有技術的持續發展。

The Chief Scientific Officer of VIRO, Harry Zhabilov, offered the following update on the production of ITV-1 vials for the Africa initiative and European Medicines Agency ("EMA") permitting progress, "Production of the necessary anti-HIV immunotherapy treatments for use in the hospitals located in Central and Eastern regions of Africa was successfully completed on April 12, 2023, and will be delivered to the hospitals in the coming weeks." With the preliminary results of Toxicology studies of the Company's ITV-1 anti-HIV therapeutic confirming that the therapy is non-toxic and demonstrating the safety of administration of this patented proprietary immunotherapy, VIRO has negotiating a contract with a German company to perform the pharmacokinetics methodology the EMA has required as part of the EMA permitting process. VIRO wishes to recognize the contribution that Dr. Lachezar Ivanov has made in this endeavor."

VIRO 首席科學官哈里·扎比洛夫提供了以下關於爲非洲倡議和歐洲藥品管理局(“EMA”)生產 ITV-1 小瓶的最新情況,允許取得進展,“供非洲中部和東部地區醫院使用的必要抗艾滋病毒免疫療法療法的生產已於 2023 年 4 月 12 日成功完成,並將在未來幾周內交付給醫院。”該公司 ITV-1 抗 HIV 療法的毒理學研究的初步結果證實了該療法是無毒的,並證明了這種專利專有免疫療法的給藥安全性,VIRO 正在與一家德國公司談判一份合同,以執行 EMA 要求的藥代動力學方法,這是EMA許可程序的一部分。VIRO 希望表彰博士的貢獻拉切扎爾·伊萬諾夫在這項努力中做出了努力。”

The CEO of BGEN, Dr. Gaurav Chandra, emphasized the progress being made by the Company using its Artificial Intelligence (AI) platform. "We continue to utilize our disruptive AI platform to identify conserved immutable epitopes on viruses and then produce species-specific monoclonal antibodies targeting those sites. We are advancing in production of multiple monoclonal antibodies against HIV, SARS-CoV-2, and the Feline Leukemia virus. Our AI platform drives the Company's drug discovery and development and executes our strategy to produce multiple therapeutics protected by International Patents. We take pride in strengthening our IP portfolio and protecting the anti-virus therapeutics, their production method, use in diagnostics and prognostics. Our application of Artificial Intelligence to drug formulation and creation is a move ahead of big pharma's monoclonal antibody discovery and development. We recognize that large pharmaceutical companies are now focused more than ever on the significant advantage provided by AI in creating highly successful therapeutics. We continue to engage with large pharma and discuss potential partnerships involving our AI platform."

BGEN首席執行官高拉夫·錢德拉博士強調了公司利用其人工智能(AI)平臺取得的進展。“我們將繼續利用我們的顛覆性人工智能平臺來識別病毒上保存的不可變表位,然後生產針對這些位點的物種特異性單克隆抗體。我們在針對HIV、SARS-CoV-2和貓白血病病毒的多種單克隆抗體的生產方面正在取得進展。我們的人工智能平臺推動了公司的藥物發現和開發,並執行了我們生產受國際專利保護的多種療法的戰略。我們爲加強我們的知識產權組合、保護抗病毒療法、其生產方法、在診斷和預測中的用途而感到自豪。我們將人工智能應用於藥物配方和創造,是大型製藥公司在單克隆抗體發現和開發方面向前邁出的一步。我們認識到,大型製藥公司現在比以往任何時候都更加關注人工智能在創造非常成功的療法方面提供的巨大優勢。我們將繼續與大型製藥公司接觸,並討論涉及我們的人工智能平臺的潛在合作伙伴關係。”

Enzolytics CEO Charles Cotropia stated, "Enzolytics is focused on accelerating the growth of our clinical products, technology platforms and multiple programs now in progress. This agreement with Sagaliam will allow us to accelerate progress in each of these areas."

Enzolytics首席執行官查爾斯·科特羅皮亞表示:“Enzolytics專注於加速我們目前正在進行的臨牀產品、技術平臺和多個項目的增長。與薩加拉姆的這項協議將使我們能夠加快這些領域的進展。”

Enzolytics, Inc. Overview

Enzolytics, Inc. 概述

Enzolytics, Inc. is a drug development company committed to commercializing its proprietary proteins and monoclonal antibodies to treat debilitating infectious diseases. The Company is advancing multiple therapeutics targeting numerous infectious diseases. One patented and clinically tested compound, ITV-1 (Immune Therapeutic Vaccine-1), is a suspension of Inactivated Pepsin Fraction (IPF), covered by U.S. Patent Nos. 8,066,982 and 7,479,538. Studies have shown it to be effective in treating HIV/AIDS. ITV-1 has also been shown to modulate the immune system.

Enzolytics, Inc. 是一家藥物開發公司,致力於將其專有蛋白質和單克隆抗體商業化,以治療使人衰弱的傳染病。該公司正在推進針對多種傳染病的多種療法。一種獲得專利並經過臨牀測試的化合物 ITV-1(免疫治療疫苗-1)是滅活胃蛋白酶組分(IPF)的懸浮液,受美國專利號 8,066,982 和 7,479,538 的保護。研究表明,它可以有效治療艾滋病毒/艾滋病。ITV-1 也被證明可以調節免疫系統。

The Company has proprietary technology for producing fully human monoclonal antibodies (mAbs) against infectious diseases which are currently being employed to produce monoclonal antibody therapeutics for treating the CoronaVirus (SARS-CoV-2), HIV-1 and the Feline Leukemia virus. The Company has also identified conserved epitopes on and has plans to produce mAbs targeting many other viruses, including HIV-2, Influenza A and B, H1N1 influenza, Respiratory syncytial virus (RSV), Small-Pox, Ebola Virus, Tetanus, Diphtheria, HTLV-1/2, Rabies, Herpes zoster, Varicella zoster, Anthrax, Mason-Pfizer monkey virus (MPMV) and Visna virus (VISNA). The Company has also analyzed epitopes of animal viruses and plans to produce mAbs for treating these animal viruses.

該公司擁有生產針對傳染病的全人單克隆抗體(mAB)的專有技術,這些單克隆抗體目前正用於生產用於治療冠狀病毒(SARS-CoV-2)、HIV-1 和貓白血病病毒的單克隆抗體療法。該公司還發現了針對許多其他病毒的保存表位,並計劃生產針對許多其他病毒的單克隆抗體,包括 HIV-2、甲型和乙型流感、H1N1 流感、呼吸道合胞病毒 (RSV)、小痘、埃博拉病毒、破傷風、白喉、HTLV-1/2、狂犬病、帶狀皰疹、水痘帶狀皰疹、炭疽病毒、梅森-輝瑞猴病毒 (MPMV))和維斯納病毒(VISNA)。該公司還分析了動物病毒的表位,並計劃生產用於治療這些動物病毒的單抗體。

Sagaliam Overview

薩加拉姆概述

Sagaliam is a SPAC that raised $116.5 million in its initial public offering on December 23, 2021. The current available cash after redemptions is approximately $10 million.

薩加里亞姆是一家特殊目的收購公司,在2021年12月23日的首次公開募股中籌集了1.165億美元。贖回後的當前可用現金約爲1000萬美元。

The purchase agreement between ENZC and Sagaliam requires that the sponsor agree not to sell its founder shares for a period of six months after the business combination subject to the provisions of the lock-up agreement. The sponsor believes that this "lock-up" period aligns the interests of the sponsor with those of Sagaliam's investors. As such, with certain limited exceptions, the sponsor expects to continue to be invested in the combined company after the completion of the purchase agreement.

ENZC和Sagaliam之間的收購協議要求贊助商同意在業務合併後的六個月內不出售其創始人股份,但須遵守封鎖協議的規定。保薦人認爲,這個 “封鎖” 期使保薦人的利益與薩加利亞姆投資者的利益一致。因此,除某些有限的例外情況外,保薦人預計在收購協議完成後將繼續投資合併後的公司。

Safe Harbor Statement: This news release contains forward-looking statements that involve risks and uncertainties associated with financial projections, budgets, milestone timelines, clinical development, regulatory approvals, and other risks described by Enzolytics, Inc. from time to time in its periodic reports filed with the SEC. ITV-1 is not approved by the U.S. Food and Drug Administration or by any comparable regulatory agencies elsewhere in the world.

安全港聲明:本新聞稿包含前瞻性陳述,涉及與財務預測、預算、里程碑時間表、臨牀開發、監管批准以及Enzolytics, Inc.在向美國證券交易委員會提交的定期報告中不時描述的其他風險相關的風險和不確定性。ITV-1 未獲得美國食品藥品監督管理局或世界其他地方任何類似監管機構的批准。

While Enzolytics, Inc. believes that the forward-looking statements and underlying assumptions contained therein are reasonable, any of the assumptions could be inaccurate, including, but not limited to, the ability of Enzolytics to establish the efficacy of its therapeutics in the treatment of any disease or health condition, the development of studies and strategies leading to commercialization of its therapeutics in the United States, the obtaining of funding required to carry out the development plan, the completion of studies and tests on time or at all, and the successful outcome of such studies or tests. Therefore, there can be no assurance that the forward-looking statements included in this release will prove to be accurate.

儘管 Enzolytics, Inc. 認爲其中包含的前瞻性陳述和基本假設是合理的,但任何假設都可能不準確,包括但不限於Enzolytics確定其療法在治療任何疾病或健康狀況方面的療效的能力、制定導致其療法在美國商業化的研究和戰略、獲得執行開發計劃所需的資金、完成研究以及準時或完全進行測試,以及此類研究或測試的成功結果。因此,無法保證本新聞稿中包含的前瞻性陳述會被證明是準確的。

Such forward-looking statements are based on current expectations. They involve inherent risks and uncertainties, including factors that could delay, divert or change any of the statements made, and cause actual outcomes and results to differ materially from current expectations. No forward-looking statement can be guaranteed. These forward-looking statements are made as of the date of this press release. The Company expressly disclaims any intention or obligation to update the forward-looking statements or update the reasons why actual results could differ from those projected in the forward-looking statements.

此類前瞻性陳述基於當前的預期。它們涉及固有的風險和不確定性,包括可能延遲、轉移或改變任何陳述的因素,並導致實際結果和結果與當前預期存在重大差異。無法保證任何前瞻性陳述。這些前瞻性陳述截至本新聞稿發佈之日作出。公司明確表示無意或無義務更新前瞻性陳述或更新實際業績可能與前瞻性陳述中預測的結果不同的理由。

Company Contact:

公司聯繫人:

Enzolytics, Inc.
1101 Raintree Circle
Allen, Texas 75013

Enzolytics, Inc.
1101 雨樹圈
得克薩斯州艾倫 75013

SOURCE: Enzolytics, Inc.

來源: Enzolytics, Inc.


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