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Allarity Therapeutics | 8-K: Current report

Allarity Therapeutics | 8-K: Current report

Allarity Therapeutics | 8-K:重大事件
美股sec公告 ·  05/03 18:11
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On May 2, 2024, Allarity Therapeutics, Inc. announced the early conclusion of its Phase 2 clinical trial for stenoparib, a novel PARP inhibitor aimed at treating advanced recurrent ovarian cancer. The decision to end the trial ahead of schedule was based on the significant clinical benefits observed, including tumor shrinkage and long-term disease stability in heavily pre-treated patients. These promising results have provided sufficient proof of concept for stenoparib as a monotherapy, leading Allarity to focus on developing a follow-on trial with the intent of regulatory submission. The trial utilized Allarity's proprietary Drug Response Predictor (DRP®) companion diagnostic to pre-screen patients, ensuring that only those with the highest likelihood of benefit were treated. The company plans to rapidly analyze the trial data and present a more comprehensive update as soon as possible. The early trial conclusion is a significant milestone for Allarity, reflecting its commitment to addressing the urgent needs of advanced ovarian cancer patients.
On May 2, 2024, Allarity Therapeutics, Inc. announced the early conclusion of its Phase 2 clinical trial for stenoparib, a novel PARP inhibitor aimed at treating advanced recurrent ovarian cancer. The decision to end the trial ahead of schedule was based on the significant clinical benefits observed, including tumor shrinkage and long-term disease stability in heavily pre-treated patients. These promising results have provided sufficient proof of concept for stenoparib as a monotherapy, leading Allarity to focus on developing a follow-on trial with the intent of regulatory submission. The trial utilized Allarity's proprietary Drug Response Predictor (DRP®) companion diagnostic to pre-screen patients, ensuring that only those with the highest likelihood of benefit were treated. The company plans to rapidly analyze the trial data and present a more comprehensive update as soon as possible. The early trial conclusion is a significant milestone for Allarity, reflecting its commitment to addressing the urgent needs of advanced ovarian cancer patients.
2024年5月2日,Allarity Therapeutics, Inc.宣布其针对stenoparib的2期临床试验提前结束,stenoparib是一种旨在治疗晚期复发性卵巢癌的新型PARP抑制剂。提前结束试验的决定是基于观察到的显著临床益处,包括大量预治疗患者的肿瘤萎缩和长期疾病稳定性。这些令人鼓舞的结果为stenoparib作为单一疗法的概念提供了足够的证据,使Alarity专注于开发一项后续试验,目的是向监管机构申报。该试验使用了Alarity专有的药物反应预测器(DRP®)伴随诊断来对患者进行预筛查,确保只有获益可能性最高的患者才能接受治疗。该公司计划快速分析试验数据,并尽快提供更全面的最新情况。早期的试验结论对Allarity来说是一个重要的里程碑,反映了其对解决晚期卵巢癌患者迫切需求的承诺。
2024年5月2日,Allarity Therapeutics, Inc.宣布其针对stenoparib的2期临床试验提前结束,stenoparib是一种旨在治疗晚期复发性卵巢癌的新型PARP抑制剂。提前结束试验的决定是基于观察到的显著临床益处,包括大量预治疗患者的肿瘤萎缩和长期疾病稳定性。这些令人鼓舞的结果为stenoparib作为单一疗法的概念提供了足够的证据,使Alarity专注于开发一项后续试验,目的是向监管机构申报。该试验使用了Alarity专有的药物反应预测器(DRP®)伴随诊断来对患者进行预筛查,确保只有获益可能性最高的患者才能接受治疗。该公司计划快速分析试验数据,并尽快提供更全面的最新情况。早期的试验结论对Allarity来说是一个重要的里程碑,反映了其对解决晚期卵巢癌患者迫切需求的承诺。

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