Amvuttra于2022年获批用于治疗一种相关联的神经性质疾病，现在将可用于治疗ATTR-CM。这是一种进行性疾病，当蛋白质发生畸变并在心脏中积聚时就会发生。数据统计显示，美国每年约有5,000至7,000人被诊断为ATTR-CM，但多家制药公司表示，这种疾病的确诊数量和规模在很大程度上仍未被诊断发现，为多家竞争者创造了重大市场机遇。Editor's Note:Gold Mining in the US Stock MarketDaily tracking of market dynamics, insightful analysis and sorting of popular fluctuations and outstanding rising stocks, providing mooers with multi-dimensional investment opportunities for reference, helping mooers grasp investment opportunities at a glance.
1. Major drug's new indication has been approved!$Alnylam Pharmaceuticals (ALNY.US)$Last Friday, it surged nearly 12%, with the drug Amvuttra intensely competing against Pfizer.
Alnylam Pharmaceuticals announced that its drug Amvuttra has been approved for the treatment of transthyretin amyloid cardiomyopathy (ATTR-CM). This could be the most significant bullish factor for the 23-year-old American biotechnology company to date and intensifies competition with one of the largest pharmaceutical companies in the USA, Pfizer.
Amvuttra was approved in 2022 for the treatment of a related neurological disorder and is now available for treating ATTR-CM. This is a progressive disease that occurs when proteins become distorted and accumulate in the heart. Statistics show that around 5,000 to 7,000 people in the USA are diagnosed with ATTR-CM each year, but several pharmaceutical companies indicate that the number of confirmed cases and scale of this disease remain largely undiagnosed, creating significant market opportunities for multiple competitors.
2. Benefiting from the increase in shipments of Blackwell chips.$Super Micro Computer (SMCI.US)$Last Friday, the stock rose nearly 8%, and JPMorgan upgraded the rating to 'Neutral', with a Target Price of $45.
JPMorgan Analysts indicated that the struggling AI Server manufacturer Super Micro Computer benefits from increased shipments of NVIDIA's Blackwell chips, expecting that Super Micro Computer's stock price may have about a 15% upward potential. JPMorgan raised Super Micro Computer's rating from 'Shareholding' to 'Neutral', increasing the Target Price from $35 to $45.
Samik Chatterjee noted that Super Micro Computer has overcome the uncertainties related to pending documents with the USA Securities and Exchange Commission (SEC), and the demand for Blackwell servers has significantly exceeded the previous generation products, with an increase in average selling price bringing additional benefits to Super Micro Computer's revenue growth, and the revenue forecast for Super Micro Computer in fiscal year 2026 has been raised by $5 billion to $39 billion, representing a year-on-year growth of 65%.
3. The stock price reached a nearly 16-year high! Japan's financial services company$Mizuho Financial (MFG.US)$ It has risen over 23% this year, receiving a bullish outlook from 'Mad Money' Jim Cramer.
Recently, an individual investor spoke with "Big Short" Jim Cramer, discussing whether to continue buying Mizuho Financial or wait for a pullback. Cramer responded: "What I can tell you is that Warren Buffett is buying this bank. I think you should continue to Hold or Buy shares of Mizuho Bank; it’s a good investment symbol. I hope our banks can perform as well as foreign banks."
Mizuho Financial Group is a holding company based in Japan that provides financial services including banking, trust banking, and securities. It operates through the following divisions: Mizuho Bank, Ltd., Mizuho Trust Bank, Ltd., and Mizuho Securities Co., Ltd. The Mizuho Bank division includes retail, corporate, international banking, Financial Institutions, public sector, and trade services.
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