Chronic sinusitis accompanied by nasal polyps is a chronic inflammatory disease of the nasal cavity or sinuses, which can lead to the growth of soft tissues known as nasal polyps, usually characterized by an increase in eosinophil levels.
According to the Zhitong Finance APP, on January 2, the NMPA official website showed that GSK's IL-5 monoclonal antibody mepolizumab injection (Nucala) has been approved for a new indication, speculated to be for chronic sinusitis with nasal polyps.
Chronic sinusitis with nasal polyps is a chronic inflammatory disease of the nasal cavity walls or sinuses, which can lead to the growth of soft tissue called nasal polyps, usually characterized by elevated levels of eosinophils. The resulting swelling can grow in both nostrils (bilateral), greatly impacting patients due to various symptoms including nasal congestion, loss of smell, facial pressure, and nasal discharge. For severe cases, surgical treatment may be necessary. However, polyps have a strong tendency to recur, often leading to repeat surgeries.