Apichope Pharmaceutical (300723.SZ) announced that according to the notice issued by the National Medical Insurance Administration and the Ministry of Human Resources and Social Security on the 'National Basic Medical Insurance, Work Injury Insurance and Maternity Insurance Drug List (2024)' (Medicare Notice [2024] No. 33, hereinafter referred to as the '2024 National Medical Insurance Drug List'), the product Nonobetti Cholic Acid Choline Sustained-release Capsules of Guangzhou Liandun Pharmaceutical Co., Ltd., a wholly-owned subsidiary of Apichope Pharmaceutical Co., Ltd. (hereinafter referred to as the 'Company'), was included in the '2024 National Medical Insurance Drug List' for the first time through negotiation.
According to the approved drug instructions, the indication for the approved Nonobetti Cholic Acid Choline Sustained-release Capsules of the Company is: in adults on diet control: used to lower the levels of severe hypertriglyceridemia patients' triglycerides (TG) and for the treatment of patients with primary hypercholesterolemia or mixed dyslipidemia.
Nonobetti Cholic Acid Choline Sustained-release Capsules belong to the betaine class of lipid-modifying drugs, which inhibit the generation of very low-density lipoprotein cholesterol and triglycerides while increasing their breakdown metabolism, thereby reducing low-density lipoprotein cholesterol and triglycerides; they also increase the generation of apolipoproteins A1 and A11, thus raising high-density lipoprotein cholesterol.
Nonobetti Cholic Acid Choline Sustained-release Capsules (brand name: Shusuda) optimize the choline salt structure, have good water solubility, significantly improve bioavailability; once a day (135mg), once a day, can be taken without food, improving the convenience of medication. It can directly exert its effects in the body without passing through first-pass metabolism by the liver, thereby reducing the burden on the liver. The instructions point out that there is no need to adjust the dose of this product or the concomitant medication when used in combination with statin drugs.
