• FTC has sent detailed information demand to Microsoft
• Questions focus on software licensing, cybersecurity and AI

The US Federal Trade Commission has opened an antitrust investigation of Microsoft Corp., drilling into everything from the company's cloud computing and software licensing businesses to cybersecurity offerings and artificial intelligence products.

After more than a year of conducting informal interviews with competitors and business partners, antitrust enforcers have crafted a detailed request to force Microsoft to turn over information, according to people familiar with the matter. The demand, which is hundreds of pages long, has been sent to the company after FTC...