GNI at 2953, up 145 points from 2160.

Significant continued growth. Information regarding questions and answers from investors has been disclosed. On the 14th, the consolidated subsidiary Cullgen reached a merger agreement by reverse merger with Pulmatrix, which is listed on the nasdaq, anticipating other revenue of approximately 14.7 billion 64 million yen (the stock valuation gain is expected to be approximately 10.7 billion 68 million yen). However, following the rise in Pulmatrix's stock price, it was replied in this disclosure that "the stock valuation gain we will report will also increase significantly," indicating a buying advantage.

Kaiom at 219, down 47 points from 4583.

Marked decrease. It has been announced that they have received a patent examination notice in China for the patent application for the candidate antibody for cancer treatment, humanized DLK-1 antibody. It is related to the combination with lenvatinib, used as a therapeutic agent for humanized monoclonal antibodies targeting human DLK-1 and liver cell cancer. The patent has been granted in Japan, and applications are pending in the US and Europe, among others. However, Kaio BioScience's stock has sharply risen in a short period, reaching a new high for the year the day before and seems to be pressured by profit-taking selling.

Chordia at 296, up 53 points from 190A.

Marked recovery after 3 days. It has been revealed that they will present research results related to their CDK12 inhibitor in the company's pipeline at the 47th Japan Molecular Biology Society's mini-symposium and poster session to be held on November 27-29. The report discusses how CDK12 inhibitors are targeting RNA control stress via new 'RNA trucking' in addition to the known 'transcription' and how RNA trucking may influence the extent of the CDK12 inhibitor's anticancer effects, creating a buying bias due to expectations for the announcement.

Amefutasou at 1149, up 150 points.

Hitting the daily limit. Hiroshi Takahashi, the representative director, disclosed on the 22nd that he has been appointed as an expert member of the 'New Regional Economic and Living Environment Creation Conference' to be held by the Cabinet Secretariat's new headquarters for new regional economic and living environment creation, which is still regarded as a buying factor. The conference aims to advance discussions on the formulation of a basic plan for concentrated efforts over the next 10 years. AmeFukuTaiyo is considered as part of the local revitalization-related stocks, and it seems that the participation of the representative director in policy decisions is expected to boost performance.

<4166> Parentheses 781 +100

Hitting the daily price increase limit. Their proprietary fraudulent order detection service, 'O-PLUX,' has been implemented in the official online shop operated by Kamakura Kouya in Kamakura, Kanagawa Prefecture, and has been announced to be effective. Kamakura Kouya sells the popular snack 'Kurumikko,' and with the introduction of this service, the detection rate of credit card fraud has improved, reducing the workload of the staff. They particularly emphasize that in resale prevention measures, the time taken to detect fraudulent orders has been reduced by over 10%.

<4416> TrueData 463 +33

Marked increase. Tokyo Marine Holdings <8766> subsidiary, Tokyo Marine Smart Mobility (Chiyoda-ku, Tokyo), announced that they have reached a basic agreement for a business alliance aimed at reducing logistics loss and promoting business operator DX. They plan to develop and provide order quantity calculation solutions for manufacturing, wholesale, and retail businesses, store sales forecast solutions for retail and food service industries, and promotion optimization solutions for automobile dealerships by leveraging each company's characteristics and strengths.