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Tonix Pharmaceuticals Publishes Peer-Reviewed Publication In MSphere Journal Highlighting Tolerability Of Its Single-Dose Mpox And Smallpox Vaccine Candidate TNX-801, In Immune-Compromised Animals

Benzinga ·  Nov 13 22:07

The World Health Organization (WHO) declared the spread of new Clade Ib Mpox a public health emergency of international concern (PHEIC): Second Mpox-related WHO PHEIC declaration in two years

Clade Ib Mpox cases detected in 16 African countries and outside of Africa, in Sweden, Thailand, Singapore, India, Germany and England

Single-dose mpox vaccines with durable protection may be required to address global health emergency

TNX-801 was shown to be more than 10- to 1,000-fold more attenuated (or less virulent) compared to the older vaccinia smallpox vaccines: Tolerability of TNX‐801 vaccination in immune-compromised animal models supports clinical development

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