Top Wall Street analysts changed their outlook on these top names. For a complete view of all analyst rating changes, including upgrades and downgrades, please see our analyst ratings page.

• Needham analyst David Saxon initiated coverage on Align Technology, Inc. (NASDAQ:ALGN) with a Hold rating. Align Tech shares fell 0.1% to close at $233.79 on Wednesday. See how other analysts view this stock.
• Goldman Sachs analyst Charles Perron-Piche initiated coverage on SiteOne Landscape Supply, Inc. (NYSE:SITE) with a Neutral rating and announced a price target of $158. SiteOne Landscape Supply shares fell 0.5% to close at $143.29 on Wednesday. See how other analysts view this stock.
• Oppenheimer analyst Matt Biegler initiated coverage on OnKure Therapeutics, Inc. (NASDAQ:OKUR) with an Outperform rating and announced a price target of $35. OnKure Therapeutics shares fell 3.7% to close at $18.50 on Wednesday. See how other analysts view this stock.
• B. Riley Securities analyst Lucas Pipes initiated coverage on IperionX Limited (NASDAQ:IPX) with a Buy rating and announced a price target of $30. IperionX shares fell 0.1% to close at $23.28 on Wednesday. See how other analysts view this stock.
• Goldman Sachs analyst Charles Perron-Piche initiated coverage on Builders FirstSource, Inc. (NYSE:BLDR) with a Buy rating and announced a price target of $225. Builders FirstSource gained 0.7% to settle at $194.40 on Wednesday. See how other analysts view this stock.

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