The following is a summary of the Kiniksa Pharmaceuticals International, Plc (KNSA) Q2 2024 Earnings Call Transcript:

Financial Performance:

• Kiniksa reported Q2 2024 total revenue of $108.6 million, including $103.4 million from ARCALYST, reflecting a 90% year-over-year growth.

• Net loss for Q2 2024 was $3.9 million compared to net income of $15 million in Q2 2023.

• ARCALYST collaboration operating profit grew 114% year-over-year to $59.9 million.

• Anticipate a full year 2024 net sales guidance adjustment to $405 million to $415 million.

Business Progress:

• Continued strong commercial performance of ARCALYST in recurrent pericarditis, reaching an 11% penetration into the target patient population.

• Invested in sales force expansion and partnerships including with the American Heart Association and Henrik Lundqvist for disease awareness.

• Initiated a Phase 2b study of abiprubart in Sjögren's Disease, aiming to address the unmet medical needs in autoimmune diseases.

Opportunities:

• Expanded ARCALYST treatment to a broader recurrence population, providing growth potential.

• Enhanced marketing strategies and physician education to solidify ARCALYST as the standard therapy.

Risks:

• Acknowledges the gradual adaptation by prescribers and payers to recognize and treat recurrent pericarditis as a chronic condition could affect the pace of growth.

More details: Kiniksa Pharmaceuticals International IR

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