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Indivior Doses First Subject In Phase 2 Study Of INDV-2000 For Opioid Use Disorder, Assessing Safety And Efficacy Over 3 Months In Treatment-Seeking Individuals

Benzinga ·  Jun 11 02:31
  • Double-blind, placebo-controlled study aims to measure safety and efficacy of INDV-2000 over 3 months in participants with moderate to severe Opioid Use Disorder.
  • INDV-2000 is an investigational non-opioid treatment that acts through the orexin pathway, shown to play a key role in the neurobiology of substance use disorder in animals.
  • Recent animal studies have demonstrated that selective Orexin-1 receptor antagonism can reduce self-administration of opioids and synthetic opioids such as fentanyl and remifentanil
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