On August 15, Gelonghui, Sanofi, Haleon and GlaxoSmithKline PLC fell 1.92%, 5.7% and 3.03% respectively before trading. GlaxoSmithKline PLC and Sanofi defended their position at Zantac in a statement on Thursday to reassure investors about the high-profile lawsuit over the recall of heartburn drug Zantac, pointing out that since 2019, studies conducted by different institutions and companies have shown no evidence that ranitidine causes cancer. In 2019, Zantac was recalled globally for "unacceptable levels of N-nitrosodimethylamine" (N-nitrosodimethylamine is a carcinogen, or NDMA). Companies including Sanofi, GlaxoSmithKline PLC, Pfizer Inc (PFE.US) and Boehringer Ingelheim (Boehringer Ingelheim) all faced lawsuits after the recall.