Summary by Futu AI
Theriva Biologics achieved target enrollment of 92 evaluable patients in its VIRAGE Phase 2b trial of VCN-01 for metastatic pancreatic ductal adenocarcinoma (PDAC). The company is exploring potential expansion into a Phase 3 registrational trial, leveraging its Orphan Drug and Fast Track designations. Additionally, Theriva received European Orphan Medicinal Product Designation and FDA Rare Pediatric Disease Designation for VCN-01 in retinoblastoma treatment.For Q3 2024, Theriva reported a net loss of $7.7 million compared to $3.3 million in Q3 2023. Research and development expenses decreased 32% to $2.7 million, while general and administrative expenses increased to $2.3 million. The company recorded impairment charges of $2.8 million for in-process R&D and goodwill.Cash and cash equivalents stood at $16.4 million as of September 30, 2024, down from $23.2 million at year-end 2023. The company secured manufacturing funding from the Spanish Government's National Knowledge Transfer Program and placed second in Merck KGaA's EMEA Advance Biotech Grant competition.