Summary by Futu AI
Hutchmed announced the initiation of a phase I clinical trial for its Menin inhibitor, HMPL-506, in China on May 31, 2024. The drug will be used to treat hematologic malignancies. The study will be a multicenter, open-label trial that aims to evaluate the safety, pharmacokinetics, and efficacy of HMPL-506. At least 60 patients will be enrolled in the trial. The study will be led by Drs. Jianxiang Wang and Hui Wei from the Hematology Hospital of CAMS. HMPL-506 is an orally administered small molecule inhibitor that targets the Menin protein. Currently, there are no Menin inhibitors approved for marketing worldwide. Hutchmed retains all rights to HMPL-506 globally. The company is a biomedical firm that specializes in cancer and immunological disease treatment, with three drugs already on the market in China, one of which is also marketed in the USA.