Panbela Therapeutics, a clinical-stage biopharmaceutical company, reported a net loss of $25.3 million for the fiscal year ended December 31, 2023, compared to a net loss of $34.9 million for the previous year. The company's operating expenses decreased by 24.8% to $25.6 million, down from $34.1 million in 2022, primarily due to reduced legal and financial advisory expenses and a decrease in research and development costs. Despite the net loss, Panbela made progress in its clinical trials, including the initiation of the ASPIRE trial for its lead candidate ivospemin (SBP-101) for the treatment of pancreatic cancer. The company also completed a strategic acquisition of Cancer Prevention Pharmaceuticals (CPP) and raised significant capital through public offerings and warrant exercises, totaling approximately $26.1 million in net financing activities. Panbela's cash and cash equivalents stood at $2.6 million as of December 31, 2023. The company's future plans include continuing its clinical development efforts, seeking regulatory approvals, and exploring additional financing options to support operations beyond the second quarter of 2024.

Panbela Therapeutics, a clinical-stage biopharmaceutical company, reported a net loss of $25.3 million for the fiscal year ended December 31, 2023, compared to a net loss of $34.9 million for the previous year. The company's operating expenses decreased by 24.8% to $25.6 million, down from $34.1 million in 2022, primarily due to reduced legal and financial advisory expenses and a decrease in research and development costs. Despite the net loss, Panbela made progress in its clinical trials, including the initiation of the ASPIRE trial for its lead candidate ivospemin (SBP-101) for the treatment of pancreatic cancer. The company also completed a strategic acquisition of Cancer Prevention Pharmaceuticals (CPP) and raised significant capital through public offerings and warrant exercises, totaling approximately $26.1 million in net financing activities. Panbela's cash and cash equivalents stood at $2.6 million as of December 31, 2023. The company's future plans include continuing its clinical development efforts, seeking regulatory approvals, and exploring additional financing options to support operations beyond the second quarter of 2024.