Recently, Aba Chemicals Corporation's research and development team successfully published an article on industrial applications of continuous flow in the internationally renowned journal, Organic Process Research & Development (OPR&D). Nitrogen methane is a versatile and highly reactive organic C1 building block that can be rapidly and efficiently combined with carboxylic acids, phenols, alcohols, and olefins to construct esters, cyclopropyl groups, and other frameworks, as well as achieve chain and ring extension. The research and development team of Aba Chemicals Corporation used DCS/SIS control and a specially designed continuous microchannel system, gas-liquid separation system to achieve industrial-scale continuous production of anhydrous nitrogen methane. This innovation not only enhances the safety and sustainability of this process but also provides an efficient and convenient pathway for the industrial-scale synthesis of α-halo ketones and other key intermediates in the pharmaceutical and agrochemical industries.