US stocks opened mixed, with the Dow up 0.28%, the Nasdaq down 0.28%, and the S&P 500 index down 0.06%. Bitcoin fell below $61,000, and blockchain technology stocks fell across the board, with MicroStrategy down more than 5%, Marathon Digital, Canaan, Riot Platforms, and Coinbase down nearly 4%. Argenx rose more than 11%, as its new drug received FDA approval for treating neuromuscular disorders. ResMed fell more than 8%, while its competitor Eli Lilly and Co's drug Zepbound helped 52% of patients resolve sleep apnea issues in trials. RXO rose more than 11% with its acquisition of Coyote, a subsidiary of United Parcel Service, for $1 billion, propelling it into the global freight brokerage giant.